A5100630404- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Renal Diseases and Glomerulopathies
- Acute Kidney Injury Research
- Healthcare Systems and Reforms
- Climate Change and Health Impacts
- Global Health Care Issues
- Air Quality and Health Impacts
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Chronic Disease Management Strategies
- Liver Disease Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Sodium Intake and Health
- Artificial Intelligence in Healthcare
- Vasculitis and related conditions
- COVID-19 Clinical Research Studies
- Cardiovascular Health and Risk Factors
- Cardiovascular Health and Disease Prevention
- Total Knee Arthroplasty Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Health Promotion and Cardiovascular Prevention
- Erythropoietin and Anemia Treatment
- Knee injuries and reconstruction techniques
- Diverse Aspects of Tourism Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2025
Peking University First Hospital
2016-2025
Peking University
2016-2025
Ministry of Education of the People's Republic of China
2016-2025
King University
2015-2024
Zhejiang Chinese Medical University
2023-2024
City University of Macau
2024
Vividion Therapeutics (United States)
2024
Beijing Tongren Hospital
2024
Beijing International Studies University
2017-2024
Acute kidney injury (AKI) is a complex clinical disorder associated with poor outcomes. Targeted regulation of the degree inflammation has been potential strategy for AKI management. Macrophages are main effector cells inflammation. However, macrophage heterogeneity in ischemia reperfusion induced (IRI-AKI) remains unclear. Using single-cell RNA sequencing mononuclear phagocytic system murine IRI model, authors demonstrate complementary roles resident macrophages (KRMs) and monocyte-derived...
International hospital-based studies have indicated a high risk of cognitive impairment after stroke, evidence from community-based in China is scarce. To determine the prevalence post-stroke (PSCI) and its subtypes stroke survivors residing selected rural urban Chinese communities, we conducted community-based, cross-sectional study 599 patients accounting for 48% all registered 4 who had suffered confirmed strokes undergone assessments via Montreal Cognitive Assessment (MoCA), Mini-Mental...
Background Fine particulate matter (PM 2.5 ) is an important environmental risk factor for cardiopulmonary diseases. However, the association between PM and of CKD remains under-recognized, especially in regions with high levels , such as China. Methods To explore long-term exposure to ambient prevalence China, we used data from China National Survey CKD, which included a representative sample 47,204 adults. We estimated annual before survey date at each participant’s address, using...
Chronic kidney disease (CKD) leads to end-stage renal failure and cardiovascular events. An attribute these progressions is abnormalities in inflammation, which can be evaluated using the neutrophil-to-lymphocyte ratio (NLR). We aimed investigate association of NLR with progression end stage (ESRD), (CVD) all-cause mortality Chinese patients stages 1-4 CKD.Patients CKD (18-74 years age) were recruited at 39 centers 28 cities across 22 provinces China since 2011. A total 938 complete other...
Early prediction of acute kidney injury (AKI) may provide a crucial opportunity for AKI prevention. To date, no model targeting among general hospitalized patients in developing countries has been published. Here we show simple, real-time, interpretable developed from large tertiary hospital China, which validated across five independent, geographically distinct, different tiered hospitals. The containing 20 readily available variables demonstrates consistent, high levels predictive...
Although a high incidence of cardiovascular disease (CVD) is observed among chronic kidney (CKD) patients in developed countries, limited information available about CVD prevalence and risk factors the Chinese CKD population. The Cohort Chronic Kidney Disease (C-STRIDE) was established to investigate patients.
IntroductionChronic kidney disease (CKD) is an important noncommunicable globally. Overall prevalence of CKD and distribution its stages differ between countries. We postulate that these differences may not only be due to variation in risk factors but also their differential impact different populations or settings.MethodsWe used nationally representative data on the adult from both United States (US; National Health Nutrition Examination Survey [NHANES], 2009 2010, N = 5557) China (China...
OBJECTIVE The impact of the difference between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFRdiff) on diabetic microvascular complications (DMCs) remains unknown. We investigated associations eGFRdiff with overall DMCs subtypes, including retinopathy (DR), kidney disease (DKD), neuropathy (DN). RESEARCH DESIGN AND METHODS This prospective cohort study included 25,825 participants diabetes free at baseline (2006 to 2010) from UK Biobank. was calculated using both...