A5075108923- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Risk Factors
- Liver Disease Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Renal Diseases and Glomerulopathies
- Healthcare Systems and Reforms
- Chronic Disease Management Strategies
- Renal and Vascular Pathologies
- Hormonal Regulation and Hypertension
- Lipoproteins and Cardiovascular Health
- Advanced Glycation End Products research
- Blood groups and transfusion
- Health Promotion and Cardiovascular Prevention
- Hepatitis C virus research
- Birth, Development, and Health
- Artificial Intelligence in Healthcare
- Diet, Metabolism, and Disease
- Diabetes Treatment and Management
- Metabolomics and Mass Spectrometry Studies
- Retinal Imaging and Analysis
- Immunodeficiency and Autoimmune Disorders
- Parathyroid Disorders and Treatments
- Gout, Hyperuricemia, Uric Acid
Peking University First Hospital
2015-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2025
Peking University
2015-2025
Beijing Normal University
2021-2025
Ministry of Education of the People's Republic of China
2011-2024
National Health and Family Planning Commission
2014-2023
RELX Group (United States)
2019-2020
King University
2018-2020
McMaster University
2019
Ministry of Science ICT and Future Planning
2014
OBJECTIVE The impact of the difference between cystatin C- and creatinine-based estimated glomerular filtration rate (eGFRdiff) on diabetic microvascular complications (DMCs) remains unknown. We investigated associations eGFRdiff with overall DMCs subtypes, including retinopathy (DR), kidney disease (DKD), neuropathy (DN). RESEARCH DESIGN AND METHODS This prospective cohort study included 25,825 participants diabetes free at baseline (2006 to 2010) from UK Biobank. was calculated using both...
The kagome material ${\mathrm{CsTi}}_{3}{\mathrm{Bi}}_{5}$, which is isostructural to the extensively studied charge-density-wave (CDW) compound ${\mathrm{CsV}}_{3}{\mathrm{Sb}}_{5}$, exhibits intriguing electronic features within its two-dimensional lattices of titanium atoms. Here, we perform optical spectroscopic measurements together with first-principles calculations for single-crystalline ${\mathrm{CsTi}}_{3}{\mathrm{Bi}}_{5}$ investigate properties comprehensively. It found that...
Objective: To analyze the relationship between 24-hour urinary calcium (24 h UCa) level and risk of end-stage kidney disease (ESKD), cardiovascular (CVD), all-cause mortality. Methods: In Chinese Cohort Study Chronic Kidney Disease, we examined 3 375 patients aged 18-74 years with CKD stages 1-4. Kaplan-Meier survival Cox proportional hazard regression models were used to test a time-to-event association levels 24 UCa incidence ESKD, CVD, Results: During follow-up 4.17 (3.37, 5.20) years,...
Previous studies indicated that lifestyle-related cardiovascular risk factors tend to be clustered in certain individuals. However, population-based studies, especially from developing countries with substantial economic heterogeneity, are extremely limited. Our study provides updated data on the clustering of factors, as well impact lifestyle those China.A representative sample adult population China was obtained using a multistage, stratified sampling method. We investigated four disease...
Background Chronic kidney disease (CKD) is a common disorder associated with multiple adverse clinical consequences, especially cardiovascular risk and end-stage renal disease. A recent national survey demonstrated that CKD has become leading health problem in China. There an urgent need to implement in-depth investigation of the burden also explore underlying mechanisms progression it association consequences. Methods The Chinese Cohort Study Kidney Disease (C-STRIDE) first cohort It will...
Uromodulin is specifically synthesized and secreted by kidney tubular epithelial cells. Studies on the association of serum uromodulin outcomes chronic disease (CKD) are lacking. This study aimed to evaluate whether was associated with patients CKD.We measured concentrations ELISA in 2652 CKD from Chinese Cohort Study Chronic Kidney Disease (C-STRIDE) investigated patients, including end-stage (ESKD) receiving replacement therapy, cardiovascular events mortality Cox proportional hazards...
Abstract Background Previous study indicated a high prevalence of ocular fundus pathology among patients with chronic kidney disease (CKD), while the relationship between them has never been explored in Chinese Population. Methods This cross-sectional included 9 670 participants enrolled medical screening program. Ocular examination was performed by ophthalmologists using ophthalmoscopes. The presence eGFR less than 60 mL/min/1.73 m 2 and/or proteinuria defined as CKD. Results Compared to...
Chronic kidney disease (CKD) is a global public health issue. Red blood cell distribution width (RDW) recently recognized potential inflammatory marker, which mirrors the variability in erythrocyte volume. Studies indicate that elevated RDW associated with increased risk of mortality CKD patients, while evidence regarding impact on outcome limited.Altogether 523 patients stage 1-4 from single center were enrolled. We identified cutoff point for level using maximally selected log-rank...
Oncologic immunotherapy is a form of therapy intended to reactivate the immune response tumor cells using agents that modulate checkpoints, such as programmed cell death protein 1 and its ligand (PD-1/PD-L), cytotoxic T-lymphocyte-associated antigen 4. Along with activation system tumors, immune-mediated kidney side effects have been reported, most which are cases interstitial nephritis. Glomerular disease, however, appears rare. Herein, we describe patient nephrotic syndrome related...
Background and objectives: In light of the growing burden chronic kidney disease (CKD), it is particular importance to create prediction models that can assist healthcare providers in identifying cases CKD individual risk integrate risk-based care for progress management. The objective this study was develop validate a new pragmatic end-stage (ESKD) utilizing Cox proportional hazards model (Cox) machine learning (ML). Design, setting, participants, measurements: Chinese Cohort Study Chronic...
To explore the association between differences cystatin C- and creatinine-based estimated glomerular filtration rate (eGFRdiff), risk of mortality cardiovascular (CV) events in individuals with diabetes.
Chronic kidney disease (CKD) is an important public health problem worldwide. However, there are few active surveillance systems for it. The China Kidney Disease Network (CK-NET) was established as a comprehensive system CKD using various data sources. As part of this, the proposed CK-NET-Yinzhou study aims to build regional in developed coastal area obtain detailed dynamic information about and improve ability manage effectively.
Clinically, hepatitis B virus (HBV) infection is observed to be associated with nephropathy. However, previous population-based studies failed show an association between HBV and CKD. Therefore, this cross-sectional study was designed further explore association.A representative sample of 6854 Chinese adults aged 30-75 years tested for levels serum surface antigen, alanine aminotransferase (ALT), creatinine, urinary albumin/creatinine ratio, potential CKD risk factors.Neither nor elevated...
The kagome material CsTi$_3$Bi$_5$, which is isostructural to the extensively studied charge density wave (CDW) compound CsV$_3$Sb$_5$, exhibits intriguing electronic features within its two-dimensional lattices of titanium atoms. Here, we perform optical spectroscopic measurements together with first-principles calculations on single-crystalline CsTi$_3$Bi$_5$ investigate properties comprehensively. It found that overall spectra are very similar those but existence CDW instability ruled out...