A5100755546- Dialysis and Renal Disease Management
- Viral gastroenteritis research and epidemiology
- Chronic Kidney Disease and Diabetes
- Hair Growth and Disorders
- Cerebrovascular and Carotid Artery Diseases
- Parathyroid Disorders and Treatments
- Viral Infections and Vectors
- Blood Pressure and Hypertension Studies
- Risk and Safety Analysis
- Chronic Myeloid Leukemia Treatments
- Neuropeptides and Animal Physiology
- CAR-T cell therapy research
- Animal Virus Infections Studies
- Traditional Chinese Medicine Studies
- Viral Infections and Immunology Research
- Heart Failure Treatment and Management
- Mosquito-borne diseases and control
- Acute Kidney Injury Research
- Immune cells in cancer
- Virus-based gene therapy research
- Dengue and Mosquito Control Research
- Cytomegalovirus and herpesvirus research
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Intracranial Aneurysms: Treatment and Complications
First Hospital of Shijiazhuang
2023-2025
Peking University
2016-2024
Shanghai University of Electric Power
2022-2024
Shanghai Institute of Process Automation Instrumentation (China)
2024
Capital Medical University
2010-2024
Inner Mongolia Agricultural University
2024
Jilin Agricultural University
2024
Changhai Hospital
2024
Second Military Medical University
2024
Xiamen University
2023-2024
Disorders in the regulatory arm of adaptive immune system result autoimmune-mediated diseases. While systemic immunosuppression is prevailing approach to manage them, it fails achieve long-lasting remission due concomitant suppression and carries risk heightened susceptibility infections malignancies. Alopecia areata a condition characterized by localized hair loss autoimmunity. The accessibility skin allows local rather than intervention avoid broad immunosuppression. It hypothesized that...
<i>Background:</i> The apoptosis of podocytes is a characteristic event in diabetic nephropathy. aim this study was to investigate whether microRNAs (miRNAs) affect podocyte circumstances. <i>Methods:</i> Diabetic nephropathy induced DBA/2 mice by intraperitoneal injections streptozotocin, and the levels proteinuria were measured with ELISA. Apoptosis-related miRNAs screened isolated glomeruli. A conditionally immortalized mouse cell line cultured 25...
Objective: The aim of the study was to estimate long-term cost‑effectiveness a hepatitis B vaccination catch-up program among children born between 1994 and 2001 (when they were 8‑15 y old) in Shandong province, China, provide information for nationwide evaluation future policy making.Methods: We determined cost-effectiveness compared with status quo (no program). combined Decision Tree model Markov simulate clinical progression after virus (HBV) infection. Parameters models from literature,...
Background and purpose Sarcopenia is highly prevalent (28.5–40.3%) in patients undergoing hemodialysis leads to poor clinical outcomes. However, the association between muscle quality sarcopenia receiving remains unclear. Therefore, we aimed explore cross-sectional area (CSA) proton-density fat-fraction (PDFF) with hemodialysis. Methods Seventy-six for &gt; 3 months were enrolled. Their handgrip strength (HGS), short physical performance battery (SPPB) performance, appendicular skeletal...
Background The reported incidence of dengue fever increased dramatically in recent years China. This study aimed to investigate and assess the effectiveness intervention implemented a outbreak Ningbo City, Zhejiang Province, Methods Data were collected City China by field epidemiological survey according strict protocol case definition. Serum specimens all cases for diagnosis virological characteristics detected using polymerase chain reaction (PCR) gene sequencing. Vector surveillance was...
Novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) is pandemic. However, data concerning the epidemiological features, viral shedding, and antibody dynamics between asymptomatic SARS-CoV-2 carriers COVID-19 patients remain controversial. We enrolled 193 infected subjects in Ningbo Zhoushan, Zhejiang, China, from January 21 to March 6, 2020. All were followed up monitor of serum immunoglobulin M (IgM) IgG against using colloidal gold-labeled...
ABSTRACT Endovascular treatment (EVT) has been strongly recommended as a first‐line for acute ischemic strokes (AIS) caused by large vessel occlusion (LVO). To evaluate the efficacy, safety, and predictors of favorable outcomes EVT LVO‐caused AIS in both anterior posterior circulations, consecutive patients who had undergone AISs LVO were retrospectively enrolled, clinical data, symptomatic intracranial hemorrhage (sICH), modified Rankin Scale (mRS) score, mortality at 90 days analyzed. In...
Diabetic polyneuropathy (DPN) presents as a wide variety of sensorimotor symptoms and affects approximately 50% diabetic patients. Changes in the neural circuits may occur early stages diabetes are implicated development DPN. Therefore, we aimed to detect changes expression isolectin B4 (IB4, marker for nonpeptidergic unmyelinated fibers their cell bodies) calcitonin gene-related peptide (CGRP, peptidergic dorsal root ganglion (DRG) spinal cord streptozotocin (STZ)-induced type 1 rats...
The Coleman centrifugation procedure generates fractions with different adipocyte and progenitor cell densities. This study aimed to identify all that are feasible for implantation.Human lipoaspirates were processed by centrifugation. centrifugates divided arbitrarily into upper, middle, lower layers. Adipocyte viability, morphology, numbers of stromal vascular fraction cells, adipose-derived mesenchymal stem cells each layer determined. 12-week volume retention subcutaneously implanted...
Hematologic adverse events (AEs) are common and serious toxicities in patients with hematologic malignancies undergoing blinatumomab therapy. However, restrictive selection criteria pivotal clinical trials can lead to an underestimation of rare but fatal toxicities. In this study, we systematically analyzed AEs associated using the Food Drug Administration Adverse Event Reporting System (FAERS) from October 2014 December 2023. Disproportionate analysis was performed identify overreported...
Noise overexposure may induce permanent noise-induced hearing loss (NIHL). The cochlear nucleus complex (CNC) is the entry point for sensory information in central auditory system. Impairments gamma-aminobutyric acid (GABA)-mediated synaptic transmission CNC have been implicated pathogenesis of disorders. However, role protein kinase C (PKC) signaling pathway GABAergic inhibition NIHL remains elusive. Thus, we investigated alterations glutamic decarboxylase 67 (GAD67, chemical marker...
Ginsenosides Rb₁ and Rd are the two main types of ginsenosides in Panax ginseng have been used as an additive to against alopecia. However, mechanisms involved largely unknown. To determine how prevent hair loss, we topically applied protopanaxadiol-type over shaved skin B57CL/6 mice, monitored assessed them for 35 days. We then investigated effects on cell genesis different phases adult follicles (HFs), using 5-bromo-2'-deoxyuridine a marker dividing cells. Moreover, p63, specific major...
Objective: Tiny cerebral aneurysms are difficult to embolize because the aneurysm's sac is too small for a single coil, and coils within aneurysm may escape from confinement of stent.This study was performed introduce stent-assisted coil-jailing technique investigate its effect on coil embolization tiny intracranial aneurysms.Materials Methods: Sixteen patients with treated between January 2011 December 2013 were retrospectively reviewed followed-up.Results: All successfully technique, at...
Asymmetric dimethylarginine (ADMA) as a uremia toxin is accumulated in end-stage renal disease (ESRD) patients. Elevated ADMA level has been shown to be predictive of cardiovascular diseases (CVDs) and all-cause mortality ESRD. Therefore, we investigated the removal by different dialysis treatments.There were 30 each hemodialysis (HD), hemodiafiltration (HDF), peritoneal (PD) patients, healthy volunteers enrolled. The concentrations serum, urine, spent dialysate samples determined. urine...
Brain ischemia is often accompanied by brain acidosis and this can affect ischemic neuronal injury. Ischemic injury initiated a decrease in ATP production which mainly relies on mitochondrial oxidative phosphorylation. Ischemia causes dysfunction, has been found to function, suggesting that accompanying may influence neurons targeting metabolism. However, the effects of energy metabolism during lacks thorough investigation. Here, we mild significantly reduced death possibly slowing process...