Siyun Wang

ORCID: 0000-0003-2468-2483
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About
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Research Areas
  • Salmonella and Campylobacter epidemiology
  • Listeria monocytogenes in Food Safety
  • Bacteriophages and microbial interactions
  • Advanced Control Systems Optimization
  • Microbial Inactivation Methods
  • Viral gastroenteritis research and epidemiology
  • Food Safety and Hygiene
  • Fault Detection and Control Systems
  • Control Systems and Identification
  • Vibrio bacteria research studies
  • Essential Oils and Antimicrobial Activity
  • Escherichia coli research studies
  • Genomics and Phylogenetic Studies
  • Probiotics and Fermented Foods
  • Identification and Quantification in Food
  • Biosensors and Analytical Detection
  • SARS-CoV-2 detection and testing
  • Cerebrovascular and Carotid Artery Diseases
  • Radiomics and Machine Learning in Medical Imaging
  • Anomaly Detection Techniques and Applications
  • Light effects on plants
  • Retinal Imaging and Analysis
  • Advanced Optimization Algorithms Research
  • GABA and Rice Research
  • Antioxidant Activity and Oxidative Stress

Sichuan Academy of Traditional Chinese Medicine
2025

University of British Columbia
2015-2024

Fujian Medical University
2024

Air Force Medical University
2024

Peking University First Hospital
2024

Peking University
2024

Jilin University of Finance and Economics
2023

Max Delbrück Center
2023

Shenzhen Institutes of Advanced Technology
2023

Chinese Academy of Sciences
2023

Cancer-associated fibroblasts (CAFs) contributes to overall tumor progression. In the current survey, we explored ability of microRNA-20a (miR-20a) within these CAF-derived exosomes influence non-small-cell lung cancer (NSCLC)

10.1002/ctm2.989 article EN cc-by Clinical and Translational Medicine 2022-07-01

Chlorinated water is commonly used in industrial operations to wash and sanitize fresh-cut, minimally processed produce. Here we compared 42 human outbreak strains that represented nine distinct Escherichia coli O157:H7 genetic lineages (or clades) for their relative resistance chlorine treatment. A quantitative measurement of was made by comparing the extension lag phase during growth each strain under exposure sublethal concentrations sodium hypochlorite Luria-Bertani or brain heart...

10.1128/aem.00914-09 article EN Applied and Environmental Microbiology 2009-08-08

The human pathogen Listeria monocytogenes is a large concern in the food industry where its continuous detection products has caused string of recalls North America and Europe. Most recognized for ability to grow foods during refrigerated storage, L. can also tolerate several other food-related stresses with some strains possessing higher levels tolerances than others. objective this study was use combination phenotypic analyses whole genome sequencing elucidate potential relationships...

10.3389/fmicb.2017.00369 article EN cc-by Frontiers in Microbiology 2017-03-08

Since many infected people experience no or few symptoms, the SARS-CoV-2 epidemic is frequently monitored through massive virus testing of population, an approach that may be biased and difficult to sustain in low-income countries. RNA can detected stool samples, quantifying genome by RT-qPCR wastewater treatment plants (WWTPs) has been carried out as a complementary tool monitor circulation among human populations. However, measuring viral load WWTPs affected experimental environmental...

10.1016/j.envint.2021.106998 article EN cc-by-nc-nd Environment International 2021-11-23

ABSTRACT Salmonella enterica serovars Enteritidis and Typhimurium are the leading causative agents of salmonellosis in United States. S. is predominantly associated with contamination shell eggs egg products, whereas frequently linked to tainted poultry meats, fresh produce, recently, peanut-based products. Chlorine an oxidative disinfectant commonly used food industry sanitize surfaces foods processing facilities (e.g., meats). However, chlorine disinfection not always effective, as some...

10.1128/aem.00823-10 article EN Applied and Environmental Microbiology 2010-06-21

Listeria monocytogenes strains are known to harbour plasmids that confer resistance sanitizers, heavy metals, and antibiotics; however, very little research has been conducted into how may influence L. monocytogenes' ability tolerate food-related stresses. To investigate this, a library (n = 93) of plasmid sequences were compared. Plasmid divided two groups (G1 G2) based on repA phylogeny. Twenty-six unique types observed, with 13 belonging each the repA-based groups. G1 significantly (p <...

10.3390/toxins11070426 article EN cc-by Toxins 2019-07-20

Phages infecting members of the opportunistic human pathogen, Salmonella enterica, are widespread in natural environments and offer a potential source agents that could be used for controlling populations this bacterium; yet, relatively little is known about these phages. Here we describe isolation characterization 45 phages enterica from disparate geographic locations within British Columbia, Canada. Host-range profiling revealed host-specific patterns susceptibility resistance, with...

10.3390/v11090854 article EN cc-by Viruses 2019-09-14

Listeria monocytogenes continues to pose a food safety risk in ready-to-eat foods, including fresh and soft/semisoft cheeses. Despite L. being detected regularly along the cheese production continuum, variations style intrinsic/extrinsic factors throughout process (e.g., pH, water activity, temperature) affect potential for survival growth. As novel preservation strategies against growth of susceptible cheeses, researchers have investigated use various biocontrol strategies, bacteriocins...

10.1111/1541-4337.12768 article EN Comprehensive Reviews in Food Science and Food Safety 2021-05-30

The present study aimed to identify the regulatory mechanisms of red, blue, and white light on carotenoid biosynthesis in maize sprouts. Determinations carotenoid, chlorophyll phytohormone profiles, as well relative gene expression, were explored. results identified enhancement production expression. Most notably, expression levels CRY, HY5, beta-carotene 3-hydroxylase genes peaked under blue light. Photomorphogene-related hormone, auxins strigolactone was also altered different lights might...

10.1016/j.fochms.2022.100128 article EN cc-by-nc-nd Food Chemistry Molecular Sciences 2022-08-09

Abstract Aim The retina and brain share similar anatomical physiological features. Thus, retinal imaging by optical coherence tomography angiography (OCTA) might be a potential tool for the early diagnosis of diabetic cerebral small vessel disease (CSVD). In this study, we aimed to evaluate vascular density (VD) in CSVD OCTA explore associations between VD magnetic resonance (MRI) markers cognitive function. Methods total, 131 patients were enrolled, including (n = 43) non‐CSVD groups 88)....

10.1111/dom.15492 article EN cc-by-nc-nd Diabetes Obesity and Metabolism 2024-03-04

<title>Abstract</title> Background In China, the “1 + X certification” policy has significantly reformed vocational education since 2019. This research integrates Postpartum Recovery” teaching content into midwifery education. It develops “curriculum –certification” course model for majors, improves nursing skills in area, and expands professional value of maternal infant care. Methods Using analysis, we discussed formulated a curriculum credit integration. study comprehensively evaluates...

10.21203/rs.3.rs-5927398/v1 preprint EN cc-by Research Square (Research Square) 2025-02-04

Produce has become a major source of foodborne illness, and may contaminated through surface water irrigation. The objectives this study were to (i) determine the frequency verotoxigenic E. coli (VTEC), Listeria monocytogenes, Salmonella in waters used for irrigation Lower Mainland British Columbia, (ii) assess suitability fecal coliforms generic as hygiene indicators, (iii) investigate correlations environmental factors with pathogen occurrence. Water samples collected semi-monthly 18...

10.1371/journal.pone.0185437 article EN cc-by PLoS ONE 2017-09-27

Treatments for non-small cell lung cancer (NSCLC) have improved tremendously, but therapeutic resistance is a common and major clinical challenge in treatment. Methyltransferase-like 3 (METTL3) ribonucleic acid (RNA) methyltransferase that has crucial functions the development progression of cancers, including drug resistance, by regulating N6-methyladenosine (m6A) modification. However, role METTL3 NSCLC poorly understood.The expression levels AKT serine/threonine kinase 1 (AKT1) tissues...

10.21037/atm-21-6608 article EN Annals of Translational Medicine 2022-02-01

Phage therapy has shown great promise for the treatment of multidrug-resistant bacterial infections. However, lack a thorough and organized understanding phage-body interactions limited its clinical application. Here, we administered different purified phages (

10.1128/jvi.01359-23 article EN Journal of Virology 2023-12-12

The Salmonella Syst-OMICS consortium is sequencing 4,500 genomes and building an analysis pipeline for the study of genome evolution, antibiotic resistance virulence genes. Metadata, including phenotypic as well genomic data, isolates collection are provided through Foodborne database (SalFoS), at https://salfos.ibis.ulaval.ca/. Here, we present our strategy first 3,377 genomes. Our data will be used to draw potential links between strains found in fresh produce, humans, animals environment....

10.3389/fmicb.2017.00996 article EN cc-by Frontiers in Microbiology 2017-06-01
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