- Insect Pest Control Strategies
- Insect and Pesticide Research
- Vector-borne infectious diseases
- Viral Infections and Vectors
- Phytochemical compounds biological activities
- Vector-Borne Animal Diseases
- Mosquito-borne diseases and control
- Allelopathy and phytotoxic interactions
- Cholinesterase and Neurodegenerative Diseases
- Insect and Arachnid Ecology and Behavior
- Insect-Plant Interactions and Control
- Forest Insect Ecology and Management
- Entomopathogenic Microorganisms in Pest Control
- Electrochemical Analysis and Applications
- Animal Genetics and Reproduction
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- Aquaculture Nutrition and Growth
- Insect Utilization and Effects
- Plant-Microbe Interactions and Immunity
- Bioactive Compounds and Antitumor Agents
- Legume Nitrogen Fixing Symbiosis
- Marine Sponges and Natural Products
- Insect Resistance and Genetics
- Sesame and Sesamin Research
Biosensores (Spain)
2024
Rothamsted Research
2016-2022
Universidade Federal de São Carlos
2011-2020
Universidad San Pablo CEU
2013
Cancer is the second leading cause of death worldwide and there epidemiological evidence that demonstrates this tendency emerging. Naringenin (NGEN) a trihydroxyflavanone shows various biological effects such as antioxidant, anticancer, anti-inflammatory, antiviral activities. It belongs to flavanone class, which represents flavonoids with C6-C3-C6 skeleton. Flavonoids do not exhibit sufficient activity be used for chemotherapy, however they can chemically modified by complexation metals...
The activities of two triterpenoids, ocotillone and cabraleadiol, four limonoids, methyl angolensate, 3-β-deacetylfi ssinolide, 7-deacetoxy-7-oxogedunin, β-photogedunin, isolated from arillus Carapa guianensis fruits seeds Cabralea canjerana (Meliaceae), were evaluated against the fall armyworm Spodoptera frugiperda. Gedunin was used as a positive control. 7-Deacetoxy-7-oxogedunin β-photogedunin reduced pupal weight occurred with gedunin. Cabraleadiol, 7-deacetoxy-7-oxogedunin prolonged...
Six triterpenes and eight limonoids were evaluated for their capacity to inhibit the growth of three human tumour cell lines, breast adenocarcinoma (MCF-7), non-small lung cancer (NCI-H460) melanoma (A375-C5). The mechanisms involved in observed arrest four most potent compounds carried out by studying effect cycle profile programmed death. results showed that one triterpene (odoratol) two (gedunin cedrelone) caused while only gedunin cedrelone found be very inducers apoptosis.
Amblyomma sculptum is a tick affecting animal and human health across Argentina, Bolivia, Paraguay Brazil. Donkeys, Equus asinus, are known to be resistant A. sculptum, suggesting that they can produce non-host semiochemicals (allomones), as already demonstrated for some other vertebrate host/pest interactions, whereas horses, caballus, considered susceptible hosts. In this study, we tested the hypothesis donkeys natural repellents against by collecting sebum from odour extracts, identifying...
The study assessed the acaricidal properties of 20 compounds derived from essential oils against Rhipicephalus microplus tick, a significant menace to tropical livestock with considerable economic losses. A novel methodology was devised, involving determination mortality times for R. larvae upon direct contact these compounds. Mortality were compared negative control (soybean oil) and two positive controls (commercial pour-on products). Tests conducted in 48-well polyethylene plates, around...
A new series of Mannich bases derived from 2-hydroxy-1,4-naphthoquinone (lawsone), substituted benzaldehydes and two primary amines, their Cu 2+ complexes were synthesized evaluated for potential as selective cholinesterase inhibitors (ChEIs).Immobilized capillary enzyme reactors (ICERs) bearing butyrylcholinesterase (BChE) acetylcholinesterase (AChE) used not only the on-flow screening assay but also determining inhibitory potency equilibrium binding constants lead inhibitors.Eight copper...
Limonoids and triterpenes are the largest groups of secondary metabolites have notable biological activities. Meliaceae Rutaceae known for their high diversity metabolites, including limonoids, distinguished from other families due to frequent occurrence such compounds. The increased interest in crop protection associated with diverse bioactivity these compounds has made attractive search new allelopathic In study reported here we evaluated profiles four (1-4) six limonoids (5-10) Rutaceae....
Abstract The sex pheromone composition of alfalfa plant bugs, Adelphocoris lineolatus (Goeze), from Central Europe was investigated to test the hypothesis that insect species across a wide geographical area can vary in composition. Potential interactions between and known attractant, ( E )-cinnamaldehyde, were also assessed. Coupled gas chromatography-electroantennography (GC-EAG) using male antennae volatile extracts collected females, previously shown attract males field experiments,...
Beagles are less susceptible to Rhipicephalus sanguineus sensu lato tick due the production of allomones benzaldehyde and 2-hexanone. Our previous published work showed that these compounds can reduce burden on dogs. Here we tested hypothesis an increase in repellent dose release rate could efficacy persistence. Slow-release formulations compounds, with higher doses rates, were artificially-infested Ten dogs randomly assigned two groups five each. The treated group received collars...
The fall armyworm, Spodoptera frugiperda, is a polyphagous pest that causes important damage in different regions of America and mainly affects corn crops both tropical subtropical areas. Currently, control relies on transgenic plants and/or chemical pesticides. In this work, we describe insecticidal activity against the armyworm from series Mannich bases (1-10), derived 2-hydroxy-1,4-naphthoquinone (lawsone), substituted benzaldehydes, two primary amines, their Cu2+ complexes (11-20)....
Abstract Plants are equipped with various defensive attributes against herbivores, including volatile and nonvolatile compounds. In maize plants, benzoxazinoids mediate resistance some the most abundant being (2 R )‐2‐β‐D‐glucopyranosyloxy‐4‐hydroxy‐7‐methoxy‐2H‐1,4‐benzoxazin−3(4H)‐one (DIMBOA‐Glc), its corresponding aglucone 2,4‐dihydroxy‐7‐methoxy‐2H‐1,4‐benzoxazin‐3(4H)‐one (DIMBOA). Both compounds have been shown to interfere in larval development of generalist herbivores but less...