Rareș Călin Roman

ORCID: 0000-0003-0620-2845
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Research Areas
  • Dental Radiography and Imaging
  • Oral and Maxillofacial Pathology
  • Bone Tissue Engineering Materials
  • Extracellular vesicles in disease
  • Tumors and Oncological Cases
  • Dental Implant Techniques and Outcomes
  • Bone health and treatments
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Nonmelanoma Skin Cancer Studies
  • Bone Tumor Diagnosis and Treatments
  • Reconstructive Facial Surgery Techniques
  • Bone and Joint Diseases
  • Platelet Disorders and Treatments
  • Cancer Diagnosis and Treatment
  • Oral health in cancer treatment
  • Molecular Biology Techniques and Applications
  • Cutaneous Melanoma Detection and Management
  • Otolaryngology and Infectious Diseases
  • Vascular Malformations and Hemangiomas
  • Spectroscopy and Chemometric Analyses
  • Infection Control and Ventilation
  • Neuroendocrine regulation and behavior
  • Neurofibromatosis and Schwannoma Cases

Iuliu Hațieganu University of Medicine and Pharmacy
2011-2024

Background and Objectives: The research aimed at evaluating the capacity of salivary exosomal miR-10b-5p miR-486-5p for oral oropharyngeal cancer detection. Materials Methods: saliva samples were harvested from histopathological diagnosed squamous cell carcinoma patients healthy volunteer subjects. exosomes isolated by differential ultracentrifugation quantified Nano Track Analysis. microRNAs extracted quantitative Real-Time Polymerase Chain Reaction. Results: This comprised fifty...

10.3390/medicina58101478 article EN cc-by Medicina 2022-10-18

Background and Objectives: An increasing incidence of non-melanoma skin cancer (NMSC) is noted, as well an cost the treatment, with NMSC becoming a public health problem. We aimed to investigate prevalence treatment costs surgically treated from Oral Maxillofacial Surgery Department Cluj-Napoca County Hospital. Materials Methods: retrospectively analyzed clinical data charge hospitalization informatic system All patients benefited standard surgical excision reconstruction post-excisional...

10.3390/medicina59020220 article EN cc-by Medicina 2023-01-23

Raman spectroscopy recently proved a tremendous capacity to identify disease-specific markers in various (bio)samples being non-invasive, rapid, and reliable method for cancer detection. In this study, we first aimed record vibrational spectra of salivary exosomes isolated from oral oropharyngeal squamous cell carcinoma patients healthy controls using surface enhancement (SERS). Then, assessed method’s discriminate between malignant non-malignant samples by means principal component–linear...

10.3390/jpm13050762 article EN Journal of Personalized Medicine 2023-04-28

The bisphosphonate-related osteonecrosis of the jaw was first referred to in 2003. Bisphosphonates action is focused on osteoclasts. drastic inhibition osteoclastic function harmful for jaws which are only bones human skeleton relative contact with external environment. adverse effects therapy include pathology they prescribed, atypical fractures pathological bone.The aim this research analyze risk factors and treatment methods case jaws. To achieve these goals, author analyzed observation...

10.15386/cjmed-838 article EN Medicine and Pharmacy Reports 2017-12-09

: The COVID-19 era has been a bleak period for both cancer and non-cancer patients, with delayed non-emergency treatments, such as non-melanoma skin (NMSC). This study aimed to evaluate how the treatment of NMSC patients was influenced by management pandemic in an Eastern European Maxillofacial Surgery center.

10.3390/jcm13133934 article EN Journal of Clinical Medicine 2024-07-04

The principles of biomechanics comprise all the interactions between body (tissues) and forces acting upon it (directly or via different medical devices). Besides mechanical aspects, tissues response is also studied. Understanding applying these vital for researchers in field oral implantology, but they must be equally known by practitioners. From planning stages to final prosthetic restoration, are involved each every aspect. Ignoring them inevitably leads failure.The first part this paper...

10.15386/mpr-1512 article EN Medicine and Pharmacy Reports 2019-12-13

Although autologous bone graft is the gold standard in reconstruction, limited volume, morbidity associated with donor site, dificult modelling of complex forms and unpredictable rate resorption fuel researches towards development alloplastic materials as substitutes. A new fiber reinforced composite (FRC) was developed using 35% combination monomers bisphenol glycidylmethacrylate [bis-GMA], urethane dimethacrylate [UDMA], triethylene glycol [TEGDMA], hydroxyethyl methacrylate [HEMA]) 65%...

10.37358/mp.20.2.5359 article EN cc-by Materiale Plastice 2019-07-01

Despite the fact that implants are sterilized, antiseptic techniques applied and systemic antibiotics routinely administered prior to after craniofacial surgery, infection rates between 3% 40% still reported for alloplastic implants, urging implant removal. The present study focuses on development of a fiber-reinforced composite (FRC) reconstruction with antimicrobial properties.A new coated gentamicin was developed tested bacterial adherence antibacterial efficiency, using two most involved...

10.15386/cjmed-599 article EN Medicine and Pharmacy Reports 2015-12-15

The study about deformations of thermoplastic polyurethane membrane (desmopan membrane) is very important for a lot industry domains (mechanic, transport, agriculture, chemistry, medicine, ...). This paper presents an original work by Finite Elements Method (FEM) analysis desmopan membrane. Thermoplastic (desmopan), anisotropic material, made in wide range models and types. By Digital Image Correlation (DICM) we have determined mechanical characteristics [5].These with geometrical are...

10.4028/www.scientific.net/amm.841.72 article EN Applied Mechanics and Materials 2016-06-01

BACKGROUND Odontogenic keratocysts are odontogenic cysts that increase in dimension based on growth factors and have a high recurrence rate. The radiological features of can be confusing owing to their similarity with other intraosseous cysts. aim treatment is minimize patient morbidity reduce the risk recurrence, along complete surgical excision. CASE REPORT We report case young man who presented our hospital for cystic lesion located posterior left mandible clinical dentigerous cyst. was...

10.12659/ajcr.936641 article EN American Journal of Case Reports 2022-06-24

Background. Medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) are associated with severe disability continuous pain, both which very difficult to control. This study aims evaluate outcome platelet-rich fibrin (PRF) treatment compared iodoform gauze packing primary suture oral mucosa in patients MRONJ ORN. Methods. Patients suffering from ORN who were treated Oral Maxillofacial Surgery Clinic Cluj-Napoca last 10 years selected for this hospital database....

10.3390/jcm13123473 article EN Journal of Clinical Medicine 2024-06-14

Background. The management of odontogenic infections varies across the globe. To shed light on subject, this study delves into practices Oral and Maxillofacial Department at Cluj-Napoca County Hospital. Material Methods. This comprehensive retrospective analysis 10 years clinical experience covered a range factors, including demographics, investigations medical surgical treatment approaches, follow-up. Additionally, examined change in trends over course COVID-19 pandemic. Results. While head...

10.3390/jcm13144046 article EN Journal of Clinical Medicine 2024-07-10

Patients under anticoagulant treatment which needs dental extractions have a significant high risk of postoperative bleeding, in consequence they need either hospitalization or ambulatory postextractional monitoring. The objective this study was while using Surgicel® as socket local hemostat for at patients anticoagulants to prove his efficacy during clinical prospective experimental study. We followed three groups with single multiple extractions: one group oral (warfarin) and meshing...

10.37897/rjs.2015.4.5 article EN cc-by Romanian Journal of Stomatology 2015-12-31

This paper presents a study concerning new titanium-based product reached by the specific techniques of powder metallurgy. The was tested in vitro to corrosion artificial saliva and vivo biological inocuity on sheep rats for biocompatibility. chemical composition solutions used general tests were: Fusayama solution; Carter Ericsson Hank Ringer solution. exposure length 48, 720, 1440 2784 hours. On sheep, six titanium implants purity 99.89%, sintered with microporosities nanoporosities at...

10.4028/www.scientific.net/msf.672.233 article EN Materials science forum 2011-01-01

Polymers represent a novel alternative in bone regeneration.Polydioxanone combined with Pluronic was used as carrier for Oxytocin form of an interfacial deposition obtained scaffold.The low rate resorption the scaffold follow regeneration sequence assuring constant and continuous release Oxytocin.The monitored by RP-HPLC method.The separation performed on Phenomenex Luna 5µm C18 100A, 250x4.6mm,using isocratic elution acetonitrile: phosphate buffer pH 7 (30:70 v/v) mobile phase.Flow 1 ml /...

10.24193/subbchem.2020.4.05 article EN Studia Universitatis Babeș-Bolyai Chemia 2020-12-22
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