A5102957416- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Temporomandibular Joint Disorders
- Oral and Maxillofacial Pathology
- Dental Radiography and Imaging
- Facial Trauma and Fracture Management
- Orthodontics and Dentofacial Orthopedics
- Salivary Gland Tumors Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Electrospun Nanofibers in Biomedical Applications
- dental development and anomalies
- Head and Neck Surgical Oncology
- Periodontal Regeneration and Treatments
- Vascular Malformations and Hemangiomas
- Oropharyngeal Anatomy and Pathologies
- Head and Neck Cancer Studies
- Dental materials and restorations
- Sinusitis and nasal conditions
- Bone Tumor Diagnosis and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Radiation Dose and Imaging
- Radiomics and Machine Learning in Medical Imaging
- Dental Research and COVID-19
- Cancer Diagnosis and Treatment
Iuliu Hațieganu University of Medicine and Pharmacy
2016-2025
University of Oxford
2021
Universitatea Națională de Știință și Tehnologie Politehnica București
2012-2019
Vrije Universiteit Amsterdam
2013
Emergency University
2010
The restoration of extensive zygomatic complex defects is a surgical challenge owing to the difficulty accurately restoring normal anatomy, symmetry, proper facial projection and width. In present study, an post-traumatic bone defect was reconstructed using custom-made implant that made with selective laser melting (SLM) technique. computer-designed had geometry fit perfectly into without requiring any intraoperative adjustments. A one-year follow-up revealed stable outcome no complications.
Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of risks low-dose radiation exposures. The aim this work was to investigate clinical performance different CBCT acquisition protocols towards optimization Custom-made anthropomorphic phantoms were scanned using a unit in six protocols. slices blinded, randomized and presented three observers, who scored image quality 4-point scale along with their level confidence. Sharpness also...
Assessing bone density in prospective dental implant sites is crucial both for choosing the type and planning a drilling procedure that will ensure implant’s primary stability osseointegration. This study aimed to investigate possible differences between densities of various edentulous maxilla mandible. The was conducted on group forty partly patients who underwent radiological examination by scanning areas interest using cone beam computed tomography (CBCT). Hounsfield units (HU) were...
Background and Objectives: The research aimed at evaluating the capacity of salivary exosomal miR-10b-5p miR-486-5p for oral oropharyngeal cancer detection. Materials Methods: saliva samples were harvested from histopathological diagnosed squamous cell carcinoma patients healthy volunteer subjects. exosomes isolated by differential ultracentrifugation quantified Nano Track Analysis. microRNAs extracted quantitative Real-Time Polymerase Chain Reaction. Results: This comprised fifty...
Raman spectroscopy recently proved a tremendous capacity to identify disease-specific markers in various (bio)samples being non-invasive, rapid, and reliable method for cancer detection. In this study, we first aimed record vibrational spectra of salivary exosomes isolated from oral oropharyngeal squamous cell carcinoma patients healthy controls using surface enhancement (SERS). Then, assessed method’s discriminate between malignant non-malignant samples by means principal component–linear...
Background/Objectives: The integration of AI into dentistry holds promise for improving diagnostic workflows, particularly in the detection dental pathologies and pre-radiotherapy screening head neck cancer patients. This study aimed to develop validate an model detecting various conditions, with a focus on identifying teeth at risk prior radiotherapy. Methods: A YOLOv8 was trained dataset 1628 annotated panoramic radiographs externally validated 180 from multiple centers. designed detect...
Differentiating between benign and malignant parotid gland tumors (PGT) is essential for establishing the treatment strategy, which greatly influenced by tumor's histology. The objective of this study was to evaluate role MRI-based radiomics in differentiation Warthin's (WT) (MT), two entities that proved present overlapping imaging features on conventional functional MRI sequences. In retrospective study, a total 106 PGT (66 WT, 40 MT) with confirmed histology were eligible radiomic...
Background: The objective of this study was to compare the value ultrasound (US), magnetic resonance imaging (MRI), and US-guided fine-needle aspiration biopsy (FNAB) in preoperative evaluation parotid tumors. Methods: A three-year prospective study, including 35 patients, conducted. Preoperative ultrasound, MRI, FNAB were performed on each patient, after which an cytological diagnosis obtained. Each patient underwent surgical treatment. diagnoses compared with histopathological reports....
Childhood trauma defects in the head and neck area are challenging many aspects for patients surgeons. One major issue is still incomplete growth. Bone defect fixation measures have to consider biomechanical forces due bone growth from both sides, possibly influencing working against itself vice versa. A solution will be development of a stable but, at same time, quickly degradable osteosynthesis system (OSS) specifically pediatric sector. Besides physical demands, biocompatibility low risk...
An increasing number of CBCT units and a wide variability radiation doses have been reported in dentistry lately.To estimate the effective, cumulative, organ absorbed children exposed to over 2 years.A prospective study was conducted who underwent diagnostic imaging with ProMax3D machine. Organ effective were calculated by Monte Carlo simulation using 5- 8-year-old pediatric voxel phantoms. Extrapolation procedures applied for other ages protocols used clinical conditions.The median dose...
The aim of the present study was to determine value multiparametric MRI in preoperative differential diagnosis parotid tumors, which is essential for therapeutic strategy selection.A three-year prospective conducted with 65 patients. Each patient investigated preoperatively and surgical excision tumor performed. imaging compared histopathological report. Several parameters were analyzed, including T1 T2 weighted image (WI), apparent diffusion coefficient (ADC), time peak (TTP), intensity...
The aim of this study was to assess the ability MRI radiomic features differentiate between benign parotid gland tumors (BPGT) and malignant (MPGT). This retrospective included 93 patients who underwent examinations head neck region (78 presenting unique PGT, while 15 presented double PGT). A total 108 PGT with histological confirmation were eligible for analysis assigned a training group (n = 83; 58 BPGT; 25 MPGT) testing 25; 16 9 MPGT). extracted from 3D segmentations on T2-weighted...
This study aimed to assess dental care needs in Cluj region during the State of Emergency, declared due COVID-19 pandemic, compared same period year 2019. A descriptive retrospective analysis was conducted, which retrieved patients seeking emergency services at Emergency Department County General Hospital and "Iuliu Hațieganu" University Medicine Pharmacy, Cluj-Napoca, Romania, only service available April 2020. Recorded data cover month 2020 is with During 2020, 724 received care, whereas...
Non-melanoma skin cancer is one of the most frequently diagnosed cancers in human body and unfortunately incidence continues to increase. NMSC represented by basal cell carcinomas (BCCs) squamous (SCCs), which are prevalent forms, basosquamous (BSC) together with Merkel carcinoma (MCC), rare types but a very aggressive pattern poor prognosis. The pathological diagnosis hard assess without biopsy, even dermoscopy. Moreover, staging can be problematic because there no access clinically...
Dental 3D-printing technologies, including stereolithography (SLA), polyjet (triple-jetting technology), and fusion deposition modeling, have revolutionized the field of orthodontic occlusal splint manufacturing. Three-dimensional printing is now currently used in many dental fields, such as restorative dentistry, prosthodontics, implantology, orthodontics. This study aimed to assess mechanical properties 3D-printed materials compare them with conventional polymethylmethacrylate (PMMA)....
The goal of the current study was to determine mechanical proprieties polymethylmethacrylate (PMMA) and improved compound, graphene-based PMMA, with Zn Ag compare results. Scanning electron microscopy analysis samples before after test conducted. compression behavior, flexural properties, tensile strength, shape were all investigated compared between variants PMMA. Commercially available used (Orthocryl®-Dentaurum, Ispringen, Germany) salt pepper technique according manufacturer's...
Biological effects of low-dose ionizing radiation (IR) have been unclear until now. Saliva, because the ease collection, could be valuable in studying IR by means surface-enhanced Raman spectroscopy (SERS). The objective our study was to compare salivary SER spectra recorded before and after exposure case pediatric patients (PP). Unstimulated saliva collected from ten PP irradiation with a cone beam computed tomography (CBCT) machine used for diagnostic purposes. SERS measurements on dried...