A5075454305- Dental Radiography and Imaging
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- COVID-19 Clinical Research Studies
- Oral and gingival health research
- Radiation Dose and Imaging
- AI in cancer detection
- Radiomics and Machine Learning in Medical Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
- Platelet Disorders and Treatments
- Oral and Maxillofacial Pathology
- Artificial Intelligence in Healthcare and Education
- dental development and anomalies
- Forensic Anthropology and Bioarchaeology Studies
- Hemophilia Treatment and Research
- Periodontal Regeneration and Treatments
- Hemostasis and retained surgical items
- Oral and Craniofacial Lesions
- Surgical Sutures and Adhesives
- Heparin-Induced Thrombocytopenia and Thrombosis
- Radioactivity and Radon Measurements
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Acute Ischemic Stroke Management
- Advanced X-ray and CT Imaging
- Blood transfusion and management
KU Leuven
2018-2024
Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of risks low-dose radiation exposures. The aim this work was to investigate clinical performance different CBCT acquisition protocols towards optimization Custom-made anthropomorphic phantoms were scanned using a unit in six protocols. slices blinded, randomized and presented three observers, who scored image quality 4-point scale along with their level confidence. Sharpness also...
Abstract Prediction of lower third molar eruption is crucial for its timely extraction. Therefore, the primary aim this study was to investigate prediction and uprighting with assistance an artificial intelligence (AI) tool. The secondary identifying incidence fully erupted molars hygienic cleansability. In total, 771 patients having two panoramic radiographs were recruited, where first radiograph acquired at 8–15 years age (T1) second acquisition between 16 23 (T2). predictive model could...
The aim of our study was to identify and predict patients at risk impeded mandibular third molar eruption potential relation between the roots canal, based on angulations in an early development stage.A total 1011 adolescent orthodontic were included this longitudinal study.We analysed pre-eruptive rotational changes root molars 2022 panoramic radiographs (two time-points). Five variables evaluated: level, stage, treatment. angulation mean annual change assessed using a linear mixed model....
Abstract Assessing the possible biological effects of exposure to low doses ionizing radiation (IR) is one prime challenges in protection, especially medical imaging. Today, radiobiological data on cone beam CT (CBCT) related are scarce. In children and adults, induction DNA double strand breaks (DSBs) buccal mucosa cells 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) antioxidant capacity saliva samples after CBCT examination were examined. No DSBs was observed nor adults. only, an increase...
The peak of the global COVID-19 pandemic has not yet been reached, and many countries face prospect a second wave infections before effective vaccinations will be available. After an initial phase viral replication, some patients develop illness in which host thrombotic inflammatory responses seem to drive complications. Severe disease is linked high mortality, hyperinflammation, remarkably incidence events. We hypothesize crucial pathophysiological role for contact pathway coagulation...
Background Oral bleeding after dental extraction in patients on non-vitamin K oral anticoagulants (NOACs) is a frequent problem. We investigated whether 10% tranexamic acid (TXA) mouthwash decreases post-extraction treated with NOACs. Methods and findings The EXTRACT-NOAC study randomized, double-blind, placebo-controlled, multicenter, clinical trial. Patients were randomly assigned to TXA or placebo instructed use the once prior extraction, thereafter for 3 times day days. primary outcome...
Abstract Objective and background Little is known about structural mechanical properties of leukocyte‐ platelet‐rich fibrin (L‐PRF) membranes even less the influence antithrombotic drugs on L‐PRF. The aim this in vitro study therefore to investigate properties, structure cell content L‐PRF impact anticoagulant therapy Methods Blood samples were obtained from 12 volunteers supplemented with either no, 1.25 IU, 2.5 5 or 10 IU enoxaparin. characterized tensile testing, scanning electron...
The aim of this study was to examine the potential influence antithrombotics on leukocyte- and platelet-rich fibrin (L-PRF) membranes.Tensile tests cell counts were performed with L-PRF membranes originating from patients anticoagulants antiplatelets versus not taking antithrombotics.For tensile tests, 13 control patients, 12 anticoagulants, 10 donated blood. Compared controls, anticoagulated donors weaker (strength 0.57 ± 0.24 MPa vs. 0.80 0.27 MPa, p = .03) could be stretched as far (1.8...
Thromboinflammation plays a central role in severe COVID-19. The kallikrein pathway activates both inflammatory pathways and contact-mediated coagulation. We investigated if modulation of the thromboinflammatory response improves outcomes hospitalized COVID-19 patients.In this multicenter open-label randomized clinical trial (EudraCT 2020-001739-28), patients with were 1:2 to receive standard care (SOC) or SOC plus study intervention. intervention consisted aprotinin (2,000,000 IE IV four...
Background: Oral bleeding after dental extraction in patients on non-vitamin K oral anticoagulants is a frequent problem. We investigated whether 10% tranexamic acid mouthwash decreases post-extraction treated with anticoagulants. Methods: The EXTRACT-NOAC study randomized, double blind, placebo-controlled, multi-center, clinical trial. Patients were randomly assigned to or placebo mouthwash, and instructed use the prior extraction, three times day for days thereafter, followed-up seven...
Abstract Prediction of lower third molar eruption is crucial for its timely extraction. Therefore, the primary aim this study was to investigate prediction and uprighting with assistance an artificial intelligence (AI) tool. The secondary identifying incidence fully erupted molars hygienic cleansability. In total, 771 patients having two panoramic radiographs were recruited, where first radiograph acquired at 8–15 years age (T1) second acquisition between 16–23 (T2). predictive model could...