Bogdan Crișan

ORCID: 0000-0003-2898-0162
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Laser Applications in Dentistry and Medicine
  • Oral and Maxillofacial Pathology
  • Periodontal Regeneration and Treatments
  • Dental Implant Techniques and Outcomes
  • Dental Radiography and Imaging
  • Radiation Dose and Imaging
  • Graphene and Nanomaterials Applications
  • Laser-Ablation Synthesis of Nanoparticles
  • Vascular Malformations and Hemangiomas
  • Mesenchymal stem cell research
  • Oral microbiology and periodontitis research
  • Orthopaedic implants and arthroplasty
  • Oral and Craniofacial Lesions
  • Dental materials and restorations
  • Electrospun Nanofibers in Biomedical Applications
  • Orthodontics and Dentofacial Orthopedics
  • Dental Anxiety and Anesthesia Techniques
  • Nanoparticles: synthesis and applications
  • Temporomandibular Joint Disorders
  • HIV/AIDS oral health manifestations
  • Advanced X-ray and CT Imaging
  • Ocular and Laser Science Research
  • Medical and Biological Ozone Research
  • Dermatologic Treatments and Research

Iuliu Hațieganu University of Medicine and Pharmacy
2014-2024

Cone beam CT (CBCT) for dentomaxillofacial paediatric assessment has been widely used despite the uncertainties of risks low-dose radiation exposures. The aim this work was to investigate clinical performance different CBCT acquisition protocols towards optimization Custom-made anthropomorphic phantoms were scanned using a unit in six protocols. slices blinded, randomized and presented three observers, who scored image quality 4-point scale along with their level confidence. Sharpness also...

10.1038/s41598-019-41949-w article EN cc-by Scientific Reports 2019-04-02

We aimed to demonstrate that DF stem cells from impacted molars and canines can be used improve bone regeneration on titanium implants surfaces. This study highlights the presence of in DF, their potential adhere differentiate into osteoblasts different types Isolated harvested tissue canine/molars, expressed markers. Differentiation was induced or absence BMP-2 TGFβ1. The growth factors until 28 days medium maintained an earlier stage differentiation with a lower level specific proteins...

10.1186/s12896-015-0229-6 article EN cc-by BMC Biotechnology 2015-12-01

Abstract The purpose of this study was to evaluate the biocompatibility some composites consisting different proportions graphene in combination with gold nanoparticles (AuNPs) and nanostructured hydroxyapatite (HA) on osteoblast viability, proliferation differentiation. Au/HA@graphene synthesized by catalytic chemical vapor deposition induction heating method acetylene as carbon source over an Au/HA catalyst, were characterized transmission electron microscopy, thermogravimetric analysis...

10.1002/jat.3152 article EN Journal of Applied Toxicology 2015-04-20

Dental 3D-printing technologies, including stereolithography (SLA), polyjet (triple-jetting technology), and fusion deposition modeling, have revolutionized the field of orthodontic occlusal splint manufacturing. Three-dimensional printing is now currently used in many dental fields, such as restorative dentistry, prosthodontics, implantology, orthodontics. This study aimed to assess mechanical properties 3D-printed materials compare them with conventional polymethylmethacrylate (PMMA)....

10.3390/biomedicines11082155 article EN cc-by Biomedicines 2023-07-31

Bone regeneration is a central focus of maxillofacial research, especially when dealing with dental implants or critical sized wound sites. While bone has great potential, exogenous delivery growth factors can greatly enhance the speed, duration, and quality osseointegration, making difference in patient’s life. morphogenic protein 2 (BMP-2) highly potent factor that acts as recruiting molecule for mesenchymal stromal cells, induces rapid differentiation them into osteoblasts, while also...

10.3390/app12031373 article EN cc-by Applied Sciences 2022-01-27

Abstract Assessing the possible biological effects of exposure to low doses ionizing radiation (IR) is one prime challenges in protection, especially medical imaging. Today, radiobiological data on cone beam CT (CBCT) related are scarce. In children and adults, induction DNA double strand breaks (DSBs) buccal mucosa cells 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxo-dG) antioxidant capacity saliva samples after CBCT examination were examined. No DSBs was observed nor adults. only, an increase...

10.1038/s41598-020-58746-5 article EN cc-by Scientific Reports 2020-02-07

Experimental animal models for studying the mechanisms of periodontitis and its links are a better alternative to in vitro studies. The aim this study is compare two ligature induced validate best one further use research. An experimental was performed on male Wistar rats that were divided into three groups: Test 1 (n = 10), incisor ligated, 2 molar Control 10). animals clinically evaluated at beginning end experiment by recording body weight, gingival bleeding index, tooth mobility score,...

10.3390/biology11050634 article EN cc-by Biology 2022-04-21

Bone tissue regeneration and mineralization are major challenges in the reconstruction of congenital defects, tumor resections or fractures. The natural bone is comprised unique architectural design from nanoscale to macroscale dimensions mainly composed collagen nano-fibrils nano-hydroxyapatite. Recent advances stem cell research nanotechnology have significantly influenced landscape engineering with applications regeneration. Carbon-based nanomaterials been attracting increasing attention...

10.1080/02726351.2019.1637382 article EN Particulate Science And Technology 2019-07-14

The aim of this research was to validate the use a gentamicin (GEN) and nano-hydroxiapatite (nHAP)-loaded polycaprolactone nanostructured membrane (NM) as an innovative, highly efficient, low-cost treatment for periodontitis. We conducted in vivo study on Wistar rats, which we induced periodontitis by placing silk ligatures around first right left upper molars. subjects were divided into three groups; group received no periodontal treatment, second open flap debridement, third together with...

10.3390/membranes14030060 article EN cc-by Membranes 2024-02-26

The principles of biomechanics comprise all the interactions between body (tissues) and forces acting upon it (directly or via different medical devices). Besides mechanical aspects, tissues response is also studied. Understanding applying these vital for researchers in field oral implantology, but they must be equally known by practitioners. From planning stages to final prosthetic restoration, are involved each every aspect. Ignoring them inevitably leads failure.The first part this paper...

10.15386/mpr-1512 article EN Medicine and Pharmacy Reports 2019-12-13

Background & Aims. Carbon-based nanomaterials such as carbon nanotubes, graphene oxide and have been explored by researchers well the industry. Graphene is a new nanomaterial which has commercial scientific advantages. Laser therapy proven highly useful in biomedicine, with use of different laser types energies for distinct purposes. The low level (LLLT) can anti-inflammatory, analgesic biostimulant effects. Recent research shown that radiation effects on osteoblasts. aim this study was...

10.15386/cjmed-433 article EN Medicine and Pharmacy Reports 2015-04-29

The objective of the present study was to evaluate 5-year outcome dental implant therapy and assess survival, success, biological technical complications. A periodontal prosthetic-oriented evaluation conducted on variables that can influence long-term predictability therapy. total 615 patients 1427 implants from a private clinic (MedArtis Dent, Cluj-Napoca, Romania) were enrolled in study. longitudinal cohort with data collected retrospectively physical/digital records combination...

10.3390/jcm12134275 article EN Journal of Clinical Medicine 2023-06-26

Abstract Although experimental studies in vitro and vivo have been numerous, the effects of laser irradiation on human fibroblast cells are poorly understood. The aim this study was to assess influence three different wavelengths nanoparticles components from oral tumor. were irradiated by 830, 920, 2940 nm wavelength. incubated their mitochondrial activity assessed MTT assay at 24, 48, 72 h. It can be concluded that light with 830 wavelength stimulates compared other two wavelengths, which...

10.1080/02726351.2012.675019 article EN Particulate Science And Technology 2013-03-01

Hemangioma and vascular malformations in the field of oral maxillofacial surgery is a pathology more often found recent years patients. The aim this study was to evaluate efficacy laser photocoagulation performed with diode (Ga-Al-As) 980 nm wavelength treatment lesions which are located on areas, using color Doppler ultrasonography for evaluation results. We also made comparison between therapy sclerotherapy order establish protocols recommendations associated pathology. conducted...

10.1117/12.2185399 article EN Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE 2016-03-22
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