A5054569695- Bone Tissue Engineering Materials
- Hemophilia Treatment and Research
- Cancer-related gene regulation
- Mesenchymal stem cell research
- Dental Implant Techniques and Outcomes
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Platelet Disorders and Treatments
- Periodontal Regeneration and Treatments
- Chronic Myeloid Leukemia Treatments
- Additive Manufacturing and 3D Printing Technologies
- Colorectal Cancer Treatments and Studies
- Curcumin's Biomedical Applications
- Facial Trauma and Fracture Management
- Colorectal Cancer Screening and Detection
- Spine and Intervertebral Disc Pathology
- Pluripotent Stem Cells Research
- Musculoskeletal pain and rehabilitation
- Graphene and Nanomaterials Applications
- Pain Mechanisms and Treatments
- Polymer Surface Interaction Studies
- Antimicrobial agents and applications
- Laser Applications in Dentistry and Medicine
- Dental Radiography and Imaging
- Oral microbiology and periodontitis research
Transylvania University of Brașov
2023-2024
Iuliu Hațieganu University of Medicine and Pharmacy
2017-2023
University of British Columbia
2023
Univerzitetski Klinički Centar Srbije
2023
Technical University of Cluj-Napoca
2014-2018
Institute of Oncology Prof. Dr. Ion Chiricuta
2015
We aimed to demonstrate that DF stem cells from impacted molars and canines can be used improve bone regeneration on titanium implants surfaces. This study highlights the presence of in DF, their potential adhere differentiate into osteoblasts different types Isolated harvested tissue canine/molars, expressed markers. Differentiation was induced or absence BMP-2 TGFβ1. The growth factors until 28 days medium maintained an earlier stage differentiation with a lower level specific proteins...
The development of novel biomaterials able to control cell activities and direct their fate is warranted for engineering functional bone tissues. Adding bioactive materials can improve new formation better osseointegration. Three types titanium (Ti) implants were tested in vitro biocompatibility this comparative study: Ti6Al7Nb with 25% total porosity used as controls, infiltrated using a sol-gel method hydroxyapatite (Ti HA) silicatitanate SiO2). behavior human osteoblasts was observed...
The aim of the paper is to obtain and characterize k-carrageenan–chitosan dual hydrogel multilayers shell BSA gel microcapsules, as a carrier for curcumin, possible antitumoral agent in biological studies. We used CaCO 3 template synthesize non-toxic /BSA particles microtemplates by coprecipitating CaCl 2 solution that contains dissolved BSA, with an equimolar Na CO solution. microcapsules assembled through layer-by-layer deposition technique calcium cross-linked k-carrageenan alternating...
Background and objective: The aim of the present study was to establish a new differentiation protocol using cannabidiol (CBD) vitamin D3 (Vit. D3) for better faster osteogenic dental tissue derived mesenchymal stem cells (MSCs). Materials methods: MSCs were harvested from follicle (DFSCs), pulp (DPSCs), apical papilla (APSCs) an impacted third molar 17-year old patient. isolated characterized flow cytometry; reverse transcription polymerase chain reaction (RT-PCR); osteogenic, chondrogenic,...
Bone regeneration is a central focus of maxillofacial research, especially when dealing with dental implants or critical sized wound sites. While bone has great potential, exogenous delivery growth factors can greatly enhance the speed, duration, and quality osseointegration, making difference in patient’s life. morphogenic protein 2 (BMP-2) highly potent factor that acts as recruiting molecule for mesenchymal stromal cells, induces rapid differentiation them into osteoblasts, while also...
Abstract Acquired haemophilia (AH) is a rare disorder characterized by bleeding in patients with no personal or family history of coagulation/clotting‐related diseases. This disease occurs when the immune system, mistake, generates autoantibodies that target FVIII, causing bleeding. Small RNAs from plasma collected AH ( n = 2), mild classical 3), severe 3) and healthy donors for sequencing Illumina, NextSeq500. Based on bioinformatic analysis, were compared to all experimental groups...
Transcutaneous electrical nerve stimulation (TENS) is a technique in which pulsed low-voltage currents are delivered through electrodes applied on the intact skin surface of painful area body, by using special device order to stimulate peripheral nerves including those for pain relief. This method used manage acute and chronic pain, conditions nociceptive or neuropathic origin. All clinical trials with TENS postoperative were included. Case reports, reviews, protocols, letters editor, animal...
The knowledge of how cells respond to different treatments in terms their migration potential could improve bone regeneration and osseointegration dental implants. objective this study was elucidate the effects various chemoattractants, morphogenetic protein-2 (BMP-2), low-level laser therapy (LLLT), cone beam computed tomography (CBCT) on follicle stem (DFSCs). chemoattractants used our were serum-free (SF) conditioned media that harvested from osteoblast cell cultures seeded surface...
Continuous quadratus lumborum (QL) analgesia is a new option for proximal femur surgery considered safe and effective. The purpose of this report was to show that we may not be aware all the possible complications technique, urinary retention occur even when block performed unilaterally.To an obese, intubated, mechanically ventilated, female patient, operated in prone position removal tumour, trans-muscular (TQL). We mounted catheter administered continuous infusion local anaesthetic...
This work aims to investigate the influence of surface conditioning porous Ti for enhancing its biological activity, as assessed by in vitro stem cell testing. Porous samples with an average porosity 32% were processed Powder Metallurgy dextrin a space holder. The subjected H 2 O treatment form enhanced TiO film, followed heat at 400°C and 600°C aiming crystallization as-formed amorphous titanium oxide. Samples characterization was performed Scanning Electron Microscopy (SEM), Fourier...
Alamar Blue viability assay. For testing the and proliferation rate of DF stem cells cultivated on titanium implants, seeded at a cell density 1.2 × 105 cells/well in 12-wells plates were stained with blue solution different periods time (24 h, 4 12 days). Briefly, 100 μl (Invitrogen) was added each well containing 900 μl medium or differentiation (OS OC). Each sample evaluated triplicate. After 1 h incubation dark 37 °C, transferred to another 12-well absorbance read using BioTek Synergy 2...
Background: Preoperative use of platelet function tests contributes to the decrease re-intervention rate due bleeding and necessity transfusion in coronary artery bypass grafting (CABG) patients.Aims: The aim was investigate predictive value justify routine preoperative impedance aggregometry (multiplate electrode test) these patients.Methods: A prospective observational trial which included 416 consecutive patients subjected elective isolated CABG conducted.The Multiplate ® test used assess...