- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Radiopharmaceutical Chemistry and Applications
- Respiratory and Cough-Related Research
- Drug Transport and Resistance Mechanisms
- Total Knee Arthroplasty Outcomes
- Advanced MRI Techniques and Applications
- Knee injuries and reconstruction techniques
- Pneumonia and Respiratory Infections
- Particle Detector Development and Performance
- Neuroscience and Neuropharmacology Research
- Sports injuries and prevention
- Macrophage Migration Inhibitory Factor
- Pituitary Gland Disorders and Treatments
- Elbow and Forearm Trauma Treatment
- Orthopaedic implants and arthroplasty
- Alzheimer's disease research and treatments
- Adenosine and Purinergic Signaling
- Medical Malpractice and Liability Issues
- Opioid Use Disorder Treatment
- Advanced Neuroimaging Techniques and Applications
- Growth Hormone and Insulin-like Growth Factors
- Bone Tumor Diagnosis and Treatments
- Lanthanide and Transition Metal Complexes
- Biochemical and Molecular Research
Baptist Hospital of Miami
2024
University of Miami
2014-2020
Jackson Memorial Hospital
2018-2020
University of Miami Health System
2018-2019
Cempra Pharmaceuticals (United States)
2015
Instituto Nacional de Salud
2004
Kaiser Foundation Hospital
2003
Boston University
2000
Tulane Medical Center
1988-1992
Tulane University
1988-1992
GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns patients newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non–vitamin K antagonist oral anticoagulant (NOAC), became available. This study sought to describe phase baseline data and compare these pre-NOAC era collected during 1. During 2,...
The acute GH release stimulated by the synthetic hexapeptide, His-DTrp-Ala-Trp-DPhe-Lys-NH2 [GH releasing peptide (GHRP)], was determined in 18 normal men and compared with effects of GH-releasing hormone, GHRH-(1–44)-NH2. Specificity effect assessed measurement serum PRL, LH, TSH, cortisol. GHRP administered at doses 0.1, 0.3, 1.0 μg/kg iv bolus. GHRH a dose alone together various does GHRP. No adverse clinical or laboratory abnormalities were observed response to A side-effect mild facial...
Analogs of somatostatin are being investigated clinically for the treatment various malignancies, including brain tumors. We studied ability three therapeutically promising radioactively labeled octapeptide analogs, RC-160, RC-121, and RC-161, to cross blood-brain barrier (BBB) after peripheral or central injection. After i.v. injection, intact RC-160 was recovered from blood brain. The entry rates were different each compound but generally low. By contrast, across BBB increased 220 times...
Systemic administration of luteinizing hormone-releasing hormone (LHRH) in rats has been found to influence behavior independently pituitary or ovarian function. A previous study shown that LHRH can cross the blood-brain barrier one direction, but it was not known whether this due a saturable transport system. The rate entry 125I-labeled from blood brain determined by two different single-pass methods carotid perfusion. first, multiple time point method, measures Ki slope linear regression...
Quadriceps tendon (QT)-bone autografts used during anterior cruciate ligament (ACL) reconstruction have provided comparable outcomes and decreased donor-site morbidity when compared with bone-patellar tendon-bone (BPTB) autografts. No study has directly the of all-soft tissue QT autograft that BPTB autograft.Patient-reported knee outcome scores rates postoperative complication after primary ACL are no different from at a minimum 2-year follow-up.Cohort study; Level evidence, 3.A total 75...
ABSTRACT The host-encoded Perforin-2 (encoded by the macrophage-expressed gene 1, Mpeg1 ), which possesses a pore-forming MACPF domain, reduces viability of bacterial pathogens that reside within membrane-bound compartments. Here, it is shown also restricts proliferation intracytosolic pathogen Listeria monocytogenes . Within few hours systemic infection, massive L. in Perforin -2 −/− mice leads to rapid appearance acute disease symptoms. We go on show cultured cells vacuole-to-cytosol...
Objective To evaluate changes in knee articular cartilage of novice half-marathon runners using magnetic resonance imaging T2 relaxation time mapping. Methods Healthy subjects were recruited from local running clubs who met the following inclusion criteria: (i) age 18–45 years; (ii) body mass index less than 30 kg/m 2 ; (iii) had participated one or (none within previous 6 months); (iv) run 20 km/week; (v) no injury surgery; (vi) pain. signals measured pre- and post-race to biochemical after...