- Lipoproteins and Cardiovascular Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Semiconductor materials and devices
- Peroxisome Proliferator-Activated Receptors
- Lipid metabolism and disorders
- Electronic Packaging and Soldering Technologies
- Metabolism, Diabetes, and Cancer
- 3D IC and TSV technologies
- Advancements in Photolithography Techniques
- Cancer, Lipids, and Metabolism
- Protease and Inhibitor Mechanisms
- Semiconductor materials and interfaces
- Blood Coagulation and Thrombosis Mechanisms
- Optical Coatings and Gratings
- Liver Disease Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Adhesion, Friction, and Surface Interactions
- Tribology and Lubrication Engineering
- Advanced MEMS and NEMS Technologies
- Adsorption and biosorption for pollutant removal
- Copper-based nanomaterials and applications
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Inflammatory mediators and NSAID effects
- Clinical Laboratory Practices and Quality Control
- Cholesterol and Lipid Metabolism
Libyan International Medical University
2025
Université de Sherbrooke
2021-2022
Laboratoire Nanotechnologies et Nanosystèmes
2021-2022
Centre de Nanosciences et de Nanotechnologies
2021
Tun Hussein Onn University of Malaysia
2020
Misurata University
2015
University of Monastir
2007-2014
Human Factors (Norway)
2010-2011
Accurate respiratory and metabolic status evaluation requires valid reliable arterial blood gas (ABG) analyzers. This study aimed to evaluate the analytical performance of three analyzers using total error (TE) sigma metric (SM) establish a robust framework for clinical device monitoring. The ABG (A, B, C) was evaluated third-party quality control materials from Randox® across levels pH, PCO₂, PO₂. Each level analyzed 20 times per analyzer over five days. TE SM were calculated standard...
Green tea catechins have extensively been studied for their imminent role in reducing the risk of various neurodegenerative diseases such as Parkinson's disease (PD). Understanding molecular interaction these compounds with anti-Parkinsonian drug targets is interest. The present study intended to explore binding modes having potential PD. Lamarckian genetic algorithm methodology was adopted docking simulations employing AutoDock 4.2 program. Toxicity and properties responsible good...
Peroxisome proliferator-activated receptor delta (PPAR-delta) is a transcription factor implicated in metabolism and inflammation. The +294T/C polymorphism the PPAR-delta gene associated with risk of coronary artery disease (CAD) dyslipidemic women hypercholesterolemic men. Whether this influences CAD absence dyslipidemia was not known, so we investigated possible association plasma lipid lipoprotein levels outcome normolipidemic Tunisian population. Genotyping performed by PCR-RFLP 112...
Abetalipoproteinemia (ABL; OMIM 200100) is a rare monogenic disorder of lipid metabolism characterized by reduced plasma levels total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C) and almost complete absence apolipoprotein B (apoB). ABL results from genetic deficiency in microsomal triglyceride transfer protein (MTP; 157147). In the present study we investigated two unrelated Tunisian patients, born consanguineous marriages, with severe low-density lipoprotein (LDL) apo B....
Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated transcription factor that regulates the gene expression of key proteins involved in lipid metabolism, vascular inflammation, and proliferation. PPARγ may contribute toward attenuation atherogenesis. We investigated relationship Pro 12 Ala PPARγ2 polymorphism with presence severity coronary artery disease (CAD) assessed by Gensini score (Gs).A total 239 patients 244 control individuals were for clinical, biochemical,...
Objectives In this study, we investigated the association between matrix metalloproteinase-1 (MMP-1) G-1607GG, MMP-12 A-82G and A1082G genotypes haplotypes prognosis of coronary artery disease (CAD). Methods A total 129 Tunisian patients with CAD were followed prospectively for a median 2.5 years. Genotypes determined by PCR-based restriction fragment length polymorphism. Two endpoints considered: restenosis incidence clinical vascular events (restenosis, myocardial infarction, stroke,...
An efficient method to waste utilization is successfully transform it into high value products.Chicken eggshell contain potential useful minerals of calcium carbonate in which can be processed biomaterials used biomedical application.The objective this study derived from and analyze the effect various calcination temperatures on properties carbonate.Fourier infrared (FTIR) spectroscopy indicates that all calcined samples reveals no longer present after as already converted oxide.This also...
Autosomal dominant hypercholesterolaemia (ADH) is due to defects in the LDL receptor gene ( LDLR), apolipoprotein B-100 APOB) or proprotein convertase subtilisin/kexin type 9 PCSK9). The aim of this study was identify and characterize mutations at origin ADH two Tunisian families. We found three genomic variations: (1) c.1845 + 1G > A, a splice site mutation LDLR (2) variations PCSK9 (p.Phe515Leu p.Gly670Glu) that were both reported be associated with high LDL-C levels. These results...
Packaging radio-frequency microelectromechanical systems (RF-MEMS) is mandatory for their integration in electronic systems. This paper discusses the of a Au−Ru/AlCu contact MEMS fabrication process with wafer-level packaging (WLP) step through Al−Ge eutectic bonding. The Au embedded movable fixed−fixed beam made <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$30 ~ \mu \text{m}$...
Leu162Val PPAR α and Pro12Ala γ 2 were investigated for their individual interactive impact on MS renal functionality (RF). 522 subjects biochemical anthropometric measurements. The diagnosis of was based the IDF definition (2009). HOMA used to determine HOMA- β , HOMA-S HOMA-IR from FPG FPI concentrations. RF assessed by estimating GFR. PCR-RFLP performed DNA genotyping. Allele frequencies 0.845 Pro 0.155 Ala, 0.915 Leu 0.085 Val. We showed that carriers Val 162 allele had lower urea, UA...