A5069370028- Air Quality and Health Impacts
- Vehicle emissions and performance
- Climate Change and Health Impacts
- Air Quality Monitoring and Forecasting
- Noise Effects and Management
- Atmospheric chemistry and aerosols
- Energy and Environment Impacts
- Urban Transport and Accessibility
- Research in Social Sciences
- Indoor Air Quality and Microbial Exposure
- Urban Green Space and Health
- Toxic Organic Pollutants Impact
- Environmental Justice and Health Disparities
- Respiratory Support and Mechanisms
- Biomarkers in Disease Mechanisms
- Cyclone Separators and Fluid Dynamics
- Occupational Health and Performance
- Safety Warnings and Signage
- Urban Heat Island Mitigation
- Environmental Policies and Emissions
- Icing and De-icing Technologies
- Advanced Aircraft Design and Technologies
- Abdominal Trauma and Injuries
- Wind and Air Flow Studies
- Heavy Metal Exposure and Toxicity
Finnish Institute for Health and Welfare
2009-2023
National Institutes of Health
2009-2012
University of Eastern Finland
2009-2010
Kymenlaakson keskussairaala
2009
Helmholtz Zentrum München
2009
Finnish Meteorological Institute
2006-2009
Kotka Maritime Research Centre
2009
Abstract. A series of 7-week sampling campaigns were conducted in urban background sites six European cities as follows: Duisburg (autumn), Prague (winter), Amsterdam Helsinki (spring), Barcelona (spring) and Athens (summer). The scheduled to include seasons local public health concern due high particulate concentrations or findings previously epidemiological studies. Aerosol samples collected parallel with two identical virtual impactors that divide air particles into fine (PM2.5) coarse...
Epidemiological studies have reported positive associations between the amount of green space in living environment and mental cardiovascular human health. In a search for effect mechanisms, field found short-term visits to environments be associated with psychological stress relief. Less evidence is available on physiology.To evaluate whether urban environments, comparison built-up environment, lead beneficial changes indicators health.Thirty-six adult female volunteers visited three...
We investigated the cytotoxic and inflammatory activities of size-segregated particulate samples (particulate matter, PM) from contrasting air pollution situations in Europe. Coarse (PM10−2.5), fine (PM2.5−0.2), ultrafine (PM0.2) were collected with a modified Harvard high-volume cascade impactor (HVCI). Mouse RAW 264.7 macrophages exposed to for 24 h. Selected mediators, nitric oxide (NO) cytokines (tumor necrosis factor alpha [TNFα], interleukin 6 [IL-6], macrophage protein-2 [MIP-2]),...
The authors have previously demonstrated heterogeneities in the inflammatory activities of urban air fine (PM2.5–0.2) and coarse (PM10–2.5) particulate samples collected from six European cities with contrasting pollution situations. same (10 mg/kg) were intratracheally instilled to healthy C57BL/6J mice either once or repeatedly on days 1, 3, 6 study week. lungs lavaged 24 h after single dose last repeated dosing. In both size ranges, dosing particles increased total cell number...
Inflammation is regarded as an important mechanism in mortality and morbidity associated with exposures of cardiorespiratory patients to urban air particulate matter. We investigated the association chemical composition sources fine (PM2.5−0.2) coarse (PM10−2.5) samples inflammatory activity mouse lung. The were collected during selected seasons six European cities using a high-volume cascade impactor. Healthy C57BL/6J mice intratracheally instilled single dose (10 mg/kg) samples. At 4, 12,...
We investigated the dose and time dependency of inflammatory cytotoxic responses to size-segregated urban air particulate samples in mouse lung. Coarse (PM10−2.5), fine (PM2.5−0.2), ultrafine (PM0.2) particles were collected six European cities (Duisburg, Prague, Amsterdam, Helsinki, Barcelona, Athens) selected seasons using a modified Harvard high-volume cascade impactor. Healthy C57Bl/6J mice intratracheally exposed 24-h dose-response study (1, 3, 10 mg/kg) 4-, 12-, course studies (10...
There is increasing demand for renewable energy and the use of biodiesel in traffic a major option when implying this increment. We investigated toxicological activities particulate emissions from nonroad diesel engine, operated with conventional fuel (EN590), two biodiesels: rapeseed methyl ester (RME) hydrotreated fresh vegetable oil (HVO). The engine was all fuels either or without catalyst (DOC/POC). matter (PM(1)) samples were collected dilution tunnel high-volume cascade impactor...
Epidemiological studies show heterogeneities in the particulate pollution-related exposure–effect relationships among cardiorespiratory patients, but connection to chemical composition and toxic properties of inhaled particles is largely unknown. To identify constituents sources responsible for diverse inflammatory cytotoxic effects urban air, fine (PM2.5–0.2) coarse (PM10–2.5) samples were collected during contrasting air pollution situations. We exposed mouse RAW 246.7 macrophages 24 hrs...
To compare short-term effects of fine particles (PM2.5; aerodynamic diameter <2.5 µm) from different sources on the blood levels markers systemic inflammation.We followed a panel 52 ischaemic heart disease patients 15 November 2005 to 21 April 2006 with clinic visits in every second week city Kotka, Finland, and determined nine inflammatory samples. In addition, we monitored outdoor air pollution at fixed site during study period conducted source apportionment PM2.5 using Environmental...
Land use regression (LUR) models are often used to predict long-term average concentrations of air pollutants. Little is known how well LUR personal exposure. In this study, the agreement with measured exposure was assessed. The components were particulate matter a diameter smaller than 2.5 μm (PM2.5), soot (reflectance PM2.5), nitrogen oxides (NOx), and dioxide (NO2). Helsinki, Utrecht, Barcelona, 15 volunteers (from semiurban, urban background, traffic sites) followed prescribed time...
We investigated the seasonal variations in chemical composition and vivo inflammatory activity of urban air particulate samples four size ranges (PM(10-2.5), PM(2.5-1), PM(1-0.2), PM(0.2)). The were collected Helsinki using a high-volume cascade impactor (HVCI). Healthy C57BL/6J mice intratracheally instilled with single dose (10 mg/kg) samples. lungs lavaged bronchoalveolar lavage fluid (BALF) was assayed for indicators inflammation tissue damage: cytokines (tumor necrosis factor...
Particulate matter (PM) from mining operations, engines, and ore processing may have adverse effects on health well-being of workers population living nearby. In this study, the characteristics PM in an underground chrome mine were investigated Kemi, Northern Finland. The concentrations chemical composition size ranges 2.5 nm to 10 µm explored order identify sources, formation mechanisms, post-emission processes particles air. This was done by using several online instruments with high...