- Breast Cancer Treatment Studies
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
- AI in cancer detection
- Gastric Cancer Management and Outcomes
- Cervical Cancer and HPV Research
- Public Health and Nutrition
- Endometrial and Cervical Cancer Treatments
- Immunotherapy and Immune Responses
- Gestational Trophoblastic Disease Studies
- Ovarian cancer diagnosis and treatment
- Colorectal and Anal Carcinomas
- Pancreatic and Hepatic Oncology Research
- Phytoestrogen effects and research
- Prenatal Screening and Diagnostics
- Cancer-related molecular mechanisms research
- HER2/EGFR in Cancer Research
- Maternal and fetal healthcare
- Diagnosis and treatment of tuberculosis
- Breast Implant and Reconstruction
- Cutaneous Melanoma Detection and Management
- Colorectal Cancer Surgical Treatments
- Lymphoma Diagnosis and Treatment
- Marriage and Family Dynamics
Dr. Hasan Sadikin General Hospital
2015-2024
Padjadjaran University
2015-2024
Mediastinal teratoma is a rare extragonadal that frequently manifests with non-specific symptoms and commonly misdiagnosed, particularly in Indonesia, where tuberculosis (TB) endemic.
ABSTRACT Background Acral and mucosal melanomas, the most common sun‐shielded site melanoma subtypes in Asia Indonesia, often yield poor prognoses. The invasion depth reflects their progressivity, pathogenesis is influenced by vitamin D receptor (VDR) status CD8+ T‐Lymphocyte amount. This study aims to determine association between of acral melanomas with VDR immunoexpression. Methods A cross‐sectional observational was conducted on 60 formalin‐fixed paraffin‐embedded (FPPE) samples, equal...
Background: The immunotherapy approach to colorectal cancer is becoming one of the key approaches treatment. One components immune responses tumor‐infiltrating lymphocyte CD8+ cells (TILs CD8+). While chemotherapy main treatments for cancer, we need consider advanced cancer. Thus, this study aimed at finding association between TIL expression and response. Methods: This a prospective cohort with patients in Digestive Surgery division tertiary general hospital West Java, Indonesia. An...
BACKGROUND Persistent infection of high risk genotypes human papilloma virus (hrHPV) has been established as the etiological cause for cervical cancer, and most prevalent that infect tissue are HPV-16 HPV-18. However, HPV genotype profile shown to differ according geographical distribution across globe. The present study aimed determine in cancer patients from Bandung, Indonesia. METHODS During period July – November 2010 viral DNA was extracted randomly chosen biopsies subjected...
Laryngeal carcinoma is a squamous cell malignancy of larynx epithelial with the Indonesian incidence 2.0 per 100,000 men and 0.2 women. The risk factors laryngeal include age, sex, family history, smoking habit, alcohol drink, gastroesophangeal reflux disease (GERD)/ laryngopharyngeal (LPR). This study aimed to know some for mentioned in Dr. Hasan Sadikin Hospital, Bandung. Hospital-based unmatched case control was selected as methods, involving 80 patients Oncology Clinic...
Background<br />Epithelial ovarian cancer (EOC) is one of the most common cancers diagnosed in Indonesian women. A combination paclitaxel and carboplatin used to treat EOC as standard chemotherapy which known have hematologic toxicities. This study aimed investigate effect combined paclitaxel-carboplatin on status patients managed at Dr. Hasan Sadikin General Hospital, Bandung, West Java.<br /><br />Methods<br />All with confirmed pathological diagnosis Hospital...
This study aims to assess the association of subject characteristics and NRAS mutations with HER2 expression in CRC.This research is a cross-sectional study. The subjects this were colorectal cancer patients Digestive Surgery division at Dr. Hasan Sadikin Hospital. There 58 subjects. Examination was carried out by Polymerase Chain Reaction (PCR) from fresh tumour tissue obtained surgery or colonoscopy. Meanwhile, examination used Immunohistochemistry (IHC) method paraffin blocks for...
Background: Sentinel lymph node biopsy (SLNB) is now the gold standard for early breast cancer with clinically negative nodes (N0). According to Indonesian Board-Certified oncologist surgeon, learning curve evaluating fellow surgeons achieve this competency could have been shorter due COVID-19 pandemic. This study aims see if sentinel (SLN) identification can be shortened. Methods: Trainee were taught perform SLNB on patients. Intraoperative assessment and completion of axillary dissection...
Pendahuluan: Magnetic resonance imaging (MRI) merupakan modalitas penting dalam diagnosis kanker ginekologi, terutama serviks dan endometrium. Laporan kasus ini bertujuan melihat peranan MRI menentukan asal tumor, keterlibatan parametrium, metastasis kelenjar getah bening retroperitoneal.Presentasi Kasus: Pada laporan pasien didiagnosis stadium IB3 dengan banding endometrium II karena keluhan perdarahan pasca-menopause, massa di bersifat endofitik, ukuran uterus membesar. Hasil histopatologi...
Response to chemotherapy for breast cancer can be assessed using the CA 15-3 tumor marker, or through histopathological means such as Miller Payne assessment. This study aimed explore correlation between level and response in locally advanced cancer. is a cross-sectional measuring before after neoadjuvant FAC regiment. took place Dr. Hasan Sadikin Hospital Bandung, Indonesia, from January August 2022. Data on responses surgery were also collected. Thirty-nine patients admitted subjects. Most...
Abstract: Hydatidiform mole (HM) is an aberrant pregnancy characterized by atypical trophoblastic hyperplasia, hydropic chorionic villi, and deprived fetal development. There are two types of HM, ie, complete (CHM) partial (PHM). Both CHM PHM can recur; however, the recurrence very scarce compared to CHM. In this report, we present a case 33-year-old woman with recurrent for 7 times without any normal in-between. was determined histology examination. The patient underwent suction curettage...
Berat badan lahir rendah (BBLR) dan spektrum plasenta akreta (SPA) merupakan salah satu masalah kesehatan yang menyebabkan morbiditas serta mortalitas ibu janin signifikan. Pengetahuan tentang sangat penting untuk mengurangi efek buruk tersebut. Penelitian bertujuan mengetahui tingkat pengetahuan perempuan usia reproduktif mengenai BBLR SPA. Studi potong lintang berbasis masyarakat tersebut dilakukan pada bulan Agustus 2021 65 partisipan komunitas perguruan tinggi swasta di Bandung melalui...
Lipoblastoma is a benign soft tissue tumor that originates from embryonic white fat. presents as slow-growing mass commonly occurs in the extremities of young children. Histological examination remains gold standard confirming lipoblastoma; however, radiology can help identify and evaluate extent characterization prior to excision. Here, we report 7-year-old male patient who presented with painless right popliteal extending proximal cruris areas, imaging modalities suggested presence fat...
<title>Abstract</title> Background Lymph node (LN) metastasis is a poor prognostic factor for cervical squamous cell carcinoma (SCC). One important predictor of LN lymphocytic inflammatory reaction, which may be indicated by infiltration CD103 + CD8 T cells. will bind to its ligand, E-cadherin causes enhancement cells cytotoxic function against tumor This study aims examine the relationship between and immunoexpression with pelvic metastases in SCC. Methods A formalin-fixed paraffin-embedded...
An adolescent IDU presented with persistent fever and cough. Echocardiography revealed dextrocardia, severe tricuspid regurgitation, vegetation on the leaflet. CT pulmonary angiography identified multiple infarcts, blood cultures confirmed Staphylococcus aureus infection. The patient was diagnosed right-sided infective endocarditis (IE) complicated by septic emboli. She treated antibiotics followed cardiac surgery. While role of dextrocardia in IE is not well established, it significantly...
We present a case of late endograft infection that progressed to the left iliac and femoral arteries, leading lower extremity gangrene, patient's death.
BACKGROUND Gestational trophoblastic disease (GTD) encompasses a group of disorders that arise from abnormal growth tissue. The spectrum GTD includes 2 major groups: benign and malignant. form is hydatidiform mole, either complete or partial; the malignant forms, referred to as gestational neoplasia (GTN), consist invasive moles, choriocarcinomas, placental site tumors, epithelioid tumors. Most patients who undergo evacuation mole by curettage have disease-free period before new tumor...
Background: Breast carcinoma is a cancer with the highest number in women, Luminal B of all types invasive breast world. Invasive luminal hormone-receptor positive (estrogen-receptor and/or progesterone-receptor positive), and either HER2 or negative high levels Ki-67. Determining aggressiveness factor very important. PD-L1 checkpoint cell immunity cycle that affects tumour cells CD133 cancerous stem marker plays role proliferation, renewal invasion cells. This study aims to determine...
BACKGROUND: Borderline ovarian tumor (BOT) is an epithelial with atypical proliferation without stromal invasion. BOTs may have aggressive fashion associated microinvasion feature, peritoneal “implants,” regional lymphadenopathy, and higher International Federation of Gynecology Obstetrics (FIGO) stage. CD133 cancer stem cells (CSCs) marker that promotes cell invasion through induction nuclear factor kappa B upregulation MMP9. Aldehyde dehydrogenase 1A1 (ALDH1A1) CSCs the c-MYC...
BackgroundThe incidence of cervical cancer was continues to increase even though various risk factors and prevention efforts have been made.Cervical begins with the development a precancerous lesion (Cervical Intraepithelial Neoplasia/CIN) which is an abnormalcell growth in epithelium. This study aims see proportion for CIN patients at Dr.Hasan Sadikin, Bandung.MethodsThis used cross-sectional retrospective descriptive research method using secondary data periodJanuary 2016 - December 2020...