A5083883415- Entomopathogenic Microorganisms in Pest Control
- Plant Pathogens and Fungal Diseases
- Diet and metabolism studies
- Plant and fungal interactions
- Nematode management and characterization studies
- Mycorrhizal Fungi and Plant Interactions
- Insect and Arachnid Ecology and Behavior
- Psychedelics and Drug Studies
- Heavy Metal Exposure and Toxicity
- Dietary Effects on Health
- Mycotoxins in Agriculture and Food
- Forest Insect Ecology and Management
- Air Quality and Health Impacts
- Metabolomics and Mass Spectrometry Studies
- Telomeres, Telomerase, and Senescence
- Air Quality Monitoring and Forecasting
- Liver Disease Diagnosis and Treatment
- Heavy metals in environment
- Fungal Biology and Applications
- Advanced Proteomics Techniques and Applications
- Insects and Parasite Interactions
- Mass Spectrometry Techniques and Applications
- Insect and Pesticide Research
- Ion-surface interactions and analysis
West Virginia University
2018-2020
National Institute for Occupational Safety and Health
2019-2020
Entomopathogenic fungi routinely kill their hosts before releasing infectious spores, but a few species keep insects alive while sporulating, which enhances dispersal. Transcriptomics- and metabolomics-based studies of entomopathogens with post-mortem dissemination from parasitized have unraveled infection processes host responses. However, the mechanisms underlying active spore transmission by Entomophthoralean in living remain elusive. Here we report discovery, through metabolomics,...
The fungal genus Massospora (Zoopagomycota: Entomophthorales) includes more than a dozen obligate, sexually transmissible pathogenic species that infect cicadas (Hemiptera) worldwide. At least two are known to produce psychoactive compounds during infection, which has garnered considerable interest for this enigmatic genus. As with many Entomophthorales, the evolutionary relationships and host associations of spp. not well understood. acquisition M. diceroproctae from Arizona, tettigatis...
Abstract The objective of the current study was to determine if age, diet, and genetic disposition (animal strain) in an animal model had early effects on specific molecular markers circulating peripheral blood mononuclear cells (PBMCs). Three strains [Sprague-Dawley (SD), Fischer 344 (F344), Brown-Norway (BN)] male rats were maintained a high-fat (HF) or regular diet. Blood collected at 4, 12, 24 wk assess chemistry recover PBMCs. Triglycerides body weight gain increased all time points HF...
It is estimated that greater than 1 million workers are exposed to welding fume (WF) by inhalation daily. The potentially toxic metals found in WF known cause multiple adverse pulmonary and systemic effects, including cardiovascular disease, these have also been shown translocate the liver. This occupational exposure combined with a high fat (HF) Western diet, which has hyperlipidemia non-alcoholic fatty liver disease (NAFLD), potential significant mixed metabolic changes goal of this study...
The goal of this study was to use liquid chromatography mass spectrometry assess metabolic changes two different diets in three distinct rat strains. Sprague-Dawley, Fischer 344, and Brown-Norway male rats were maintained on a high-fat, or regular diet for 24 weeks. Liver tissue collected at 4, 12, weeks global small molecule metabolite using high resolution accurate coupled ultra-high-performance chromatography. results the metabolomics analysis revealed significant based both age within...
Abstract The fungal genus Massospora (Zoopagomycota: Entomophthorales) includes more than a dozen obligate, sexually transmissible pathogenic species that infect cicadas (Hemiptera) worldwide. At least two are known to produce psychoactive compounds during infection, which has garnered considerable interest for this enigmatic genus. As with many Entomophthorales, the evolutionary relationships and host associations of spp. not well understood. acquisition M. diceroproctae from Arizona,...
Abstract Entomopathogenic fungi routinely kill their hosts before releasing infectious spores, but select species keep insects alive while sporulating, which enhances dispersal. Transcriptomics and metabolomics studies of entomopathogens with post-mortem dissemination from parasitized have unraveled infection processes host responses, yet mechanisms underlying active spore transmission by Entomophthoralean in living remain elusive. Here we report the discovery, through metabolomics,...
Abstract Fungivorous millipedes (subterclass Colobognatha) likely represent some of the earliest known mycophagous terrestrial arthropods, yet their fungal partners remain elusive. Here we describe relationships between fungi and fungivorous millipede, Brachycybe lecontii . Their community is surprisingly diverse with 176 genera, 39 orders, four phyla includes several undescribed species. Of particular interest are twelve genera conserved across wood substrates millipede clades that comprise...