A5101824233- Pain Mechanisms and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Acute Kidney Injury Research
- Intensive Care Unit Cognitive Disorders
- Neuropeptides and Animal Physiology
- Neuroscience and Neuropharmacology Research
- Spine and Intervertebral Disc Pathology
- Anesthesia and Neurotoxicity Research
- Airway Management and Intubation Techniques
- Pediatric Pain Management Techniques
- Cardiac Arrest and Resuscitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Anesthesia and Sedative Agents
- Hemodynamic Monitoring and Therapy
- Botulinum Toxin and Related Neurological Disorders
- Nerve injury and regeneration
- Respiratory Support and Mechanisms
- Paraoxonase enzyme and polymorphisms
- Ion channel regulation and function
- Receptor Mechanisms and Signaling
- Sepsis Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Herpesvirus Infections and Treatments
- Hip and Femur Fractures
Beijing Friendship Hospital
2016-2025
Capital Medical University
2016-2025
Yantaishan Hospital
2024
Johns Hopkins Medicine
2020-2023
Johns Hopkins University
2020-2023
Nanjing Medical University
2018-2021
Creative Commons
2019
Beijing Chaoyang Emergency Medical Center
2018
Beijing Chao-Yang Hospital
2012-2015
First Affiliated Hospital of Wenzhou Medical University
2014-2015
Glioma is a common life-threatening tumor with high malignancy and invasiveness. LncRNA ZFPM2 antisense RNA 1 (ZFPM2-AS1) was confirmed to be implicated in numerous tumors, while its biological function mechanism have not been thoroughly understood glioma. The gene expression measured by RT-qPCR. Cell proliferation, cell cycle, apoptosis of glioma cells were validated CCK-8, colony formation, flow cytometry TUNEL assays. effect ZFPM2-AS1 on growth verified vivo assay. exploration...
Postherpetic neuralgia (PHN) and diabetes mellitus frequently coexist in clinical settings; however, the causal relationship between them remains unclear. Moreover, potential mediating role of amino acids related to neural regulation this association has not been fully explored yet. Univariable Mendelian randomized (UVMR) was utilized examine various subtypes PHN, with inverse variance weighted method as main approach. Multivariable MR (MVMR) conducted assess direct effect mellitus,...
Subcutaneous infiltration of capsaicin, which initially activates transient receptor potential vanilloid 1 (TRPV1) receptors, can subsequently desensitize TRPV1-expressing nociceptors and induce analgesia in different pain models. Yet, whether the modulation keratinocytes may also contribute to analgesic action capsaicin treatment remains unclear. In a rat model postoperative pain, we tested hypothesis that subcutaneous injection inhibited proliferation epidermal their expression...
Abstract Background: Stargazin is the first transmembrane protein known to regulate synaptic targeting of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. However, it unclear whether regulation surface delivery spinal AMPA receptor subunits by stargazin contributes postoperative pain development. Methods: Western blot analysis was used examine changes in subunits, GluR1 and GluR2, rat dorsal horn. The interaction between GluR2 examined coimmunoprecipitation. Expression...
The suprascapular nerve is situated between the prevertebral fascia and superficial layer of deep cervical on surface middle posterior scalene muscles before it reaches notch. Consequently, we hypothesized that injecting local anesthetics (LAs) there would introduce a new block approach for blocking nerve, ie, extra-prevertebral fascial block. We assessed postoperative analgesic effect, as well incidence diaphragmatic paralysis 30 minutes after
Neuroligin1 is an important synaptic cell adhesion molecule that modulates the function of synapses through protein–protein interactions. Yet, it remains unclear whether regulation transmission in spinal cord by neruoligin1 contributes to development postoperative pain. In a rat model pain induced plantar incision, we conducted Western blot study examine changes expression postsynaptic membrane neuroligin1, density 95 (PSD-95), and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA)...
Epidermal keratinocytes play a vital role in restoration of the intact skin barrier during wound healing. The negative effect hyperglycemia may prolong healing process. have been demonstrated to modulate and directly initiate nociceptive responses rat models fractures chemotherapy-induced neuropathic pain. However, it is unclear whether epidermal are involved development maintenance incisional pain nondiabetic or diabetic animals. In current study, using behavioral tests...