A5091411295- RNA modifications and cancer
- Cancer-related gene regulation
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cancer-related molecular mechanisms research
- Hepatitis C virus research
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Renal Transplantation Outcomes and Treatments
- Cancer Immunotherapy and Biomarkers
- Hybrid Renewable Energy Systems
- Renal cell carcinoma treatment
- Ferroptosis and cancer prognosis
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- Gut microbiota and health
Fujian Medical University
2022-2024
Union Hospital
2024
Army Medical University
2024
Daping Hospital
2024
Zhejiang Shuren University
2022
Zhejiang University
2022
First Affiliated Hospital of Fujian Medical University
2022
Vascular smooth muscle cell (VSMC) phenotype switching is a pathological hallmark in various cardiovascular diseases. N4-acetylcytidine (ac4C) catalyzed by N-acetyltransferase 10 (NAT10) well conserved the enzymatic modification of ribonucleic acid (RNA). NAT10-mediated ac4C acetylation involved physiological and processes, including cardiac remodelling. However, biological functions underlying regulatory mechanisms mRNA modifications vascular diseases remain elusive.
Background: Hepatocellular carcinoma (HCC) is the predominant form of liver cancer and accompanied by a complex regulatory network. Increasing evidence suggests that an abnormal gene expression EZH2 associated with HCC progression. However, molecular mechanism which non-coding RNAs (ncRNAs) regulate remains elusive. Methods: The Cancer Genome Atlas (TCGA) Genotype-Tissue Expression (GTEx) data were used to perform differential analysis prognostic analysis. We Encyclopedia RNA Interactomes...
Malignant tumor is one of the most common diseases that seriously affect human health. The prior literature has reported biological function and potential therapeutic targets SET domain bifurcated histone lysine methyltransferase 1 (SETDB1) as an oncogene. However, SETDB1 rarely been analyzed from a pan-cancer perspective.Bioinformatics analysis tools databases, including GeneCards, National Center for Biotechnology Information (NCBI), UniProt, Illustrator Biological Sequences (IBS), Human...
Background: ABO-incompatible liver transplantation (ABOi LT) under the desensitization protocol with rituximab had excellent survival outcomes comparable to those of ABO-compatible (ABOc LT). In this work, we explored effect ABOi LT on recipients from perspective biliary microbiota and metabonomics. Methods: Liver transplant (LT) treated at our center were enrolled in study. total, 6 12 ABOc enrolled, collected their bile five times (during 2 days, 1 week, weeks month after The samples used...
Stomach adenocarcinoma (STAD), is the most common histological type of gastric cancer (GC) with high mortality and poor prognosis. We sought to investigate contribution Notch receptor 1 (NOTCH1) STAD immunity.The profiles immune cells in cohorts were compared, a correlation analysis between NOTCH1 gene tumor cell infiltration was then conducted. The immune-related genes (IRGs) associated identified. Based on NOTCH1-associated IRGs, multiple-gene risk prediction signatures established....
To establish a new and accurate model for standard liver volume (SLV) estimation graft size prediction in transplantation Chinese adults.In this study, the data of morphologic indices (LV) were retrospectively obtained on 507 cadaveric donors between June 2017 September 2020 Shulan (Hangzhou) Hospital. Linear regression analysis was performed to evaluate impact each parameter develop SLV formula. The formula then validated prospectively 97 October 2021, accuracy compared with previous...