A5064457123- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Obstructive Sleep Apnea Research
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Pneumothorax, Barotrauma, Emphysema
- Medical Imaging and Pathology Studies
- Long-Term Effects of COVID-19
- Inhalation and Respiratory Drug Delivery
- Tracheal and airway disorders
- COVID-19 Clinical Research Studies
- Shoulder Injury and Treatment
- Venous Thromboembolism Diagnosis and Management
- Respiratory and Cough-Related Research
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Neuroscience of respiration and sleep
- Sarcoidosis and Beryllium Toxicity Research
- Inflammation biomarkers and pathways
- Pericarditis and Cardiac Tamponade
- Pulmonary Hypertension Research and Treatments
- Inflammatory Biomarkers in Disease Prognosis
- Sleep and Wakefulness Research
Selçuk University
2013-2024
Selçuk Üniversitesi Tıp Fakültesi Hastanesi
2011-2024
Ankara Spine Center
2022
Konya Food and Agriculture University
2021
Objective We aimed to evaluate the relationship between perceived social support, coping strategies, anxiety, and depression symptoms among hospitalized COVID-19 patients by comparing them with a matched control group in terms of age, gender, education level. Method The patient (n = 84) healthy controls (HCs, n 92) filled questionnaire including socio-demographic form, Hospital Anxiety Depression Scale, Multidimensional Perceived Social Support Brief Coping Orientation Problems Experienced...
BACKGROUND: Identifying different phenotypes of chronic obstructive pulmonary disease (COPD) is important for both therapeutic options and clinical outcome the disease. OBJECTIVE: To characterize COPD according to high‐resolution computed tomography (HRCT) findings; correlate HRCT scores obtained using modified Bhalla scoring system with physiological indicators systemic inflammation. METHODS: The present study included 80 consecutive patients stable COPD. scans were evaluated by two...
Purpose: Pulmonary fibrosis is a devastating disease with poor prognosis. Although the diagnosis and pathophysiology of this have been better characterized over past few years, there no effective therapy for disease. The aim study was to evaluate anti-inflammatory anti-fibrotic effects sirolimus (SRL), which potential agent, by using bleomycin (BLM)-induced pulmonary model in rats. Methods: A single intra-tracheal injection BLM (2.5 U/kg) administered mg/kg/day) given orally, beginning...
Obstructive sleep apnea syndrome is associated with executive cognitive impairment. An important question whether impairment in functioning obstructive independent of dysfunction attention. Attentional control a subcomponent that mediated by frontal lobe processing. In the current study, we investigated attentional deficient syndrome. processes were through conflict adaptation and frequency paradigms. These neuropsychological paradigms assessed using Simon, Flanker Stroop tasks. We...
Abstract Background and objective Recently, comorbidities such as impaired cognitive function have been attracting more focus when considering the management of chronic obstructive pulmonary disease ( COPD ). Here we investigated relationship between categories given in G lobal I nitiative for C hronic O bstructive L ung D isease GOLD ) guidelines 2011. Specifically, after controlling non‐ covariates, assessed clinical features that may be predictive impairment patients with . Methods We...
Purpose: Cisplatin and Paclitaxel are two chemotherapeutic agents known to produce neurotoxicity when used for cumulative dose regimens. In this study we aim assess their toxicity in the optic nerve, evaluate retinal nerve fibre layer (RNFL) thickness visual field changes lung cancer patients treated with Paclitaxel.Methods: Fifteen who were intravenously 75 mg/m2 cisplatin 175 paclitaxel every 3 weeks, up a maximum of six courses, enrolled prospective clinical trial. All underwent complete...
AIMS: The aim of this study was to explain the demographic data, comorbidity and laboratory fi ndings our rst cases in COVID-19 pneumonia country.METHODS: We gathered data participants from electronic medical system, including daily knowledge laboratory, radiological, microbiological results between March 10 April 7, 2020.RESULTS: Totally, 125 patients, whose were compatible with COVID-19, included study, 42 patients excluded study.The distribution genders was, 39 females (46.9 %), 44 males...
The basic uses of C-reactive protein (CRP) and procalcitonin (PCT) in clinical practice are the diagnosis follow-up infectious disease. fact that CRP already achieves high levels cases with lung cancer, however, limits its diagnostic specificity. Procalcitonin may be an important marker differential cancer patients who have fever levels. Our objective this study was to determine PCT newly diagnosed non-infectious non-small cell (NSCLC) relate these results patient disease...
To compare the efficacy of prednisolone, montelukast, and omalizumab in reducing allergic symptoms inflammation at tissue level an experimental rhinitis model. Materials methods: Forty Sprague Dawley rats were randomized into 5 groups as naive (NS/NC), sensitized/challenged (S/C) by subcutaneous ovalbumin antigen injection, montelukast-, prednisolone-, omalizumab-treated groups. A nasal allergen challenge was performed every day from 20 to 26. The number sneezes nasal/eye rubbing movements,...
Abstract The novel coronavirus disease 2019 (COVID‐19) remains a global health emergency, and understanding the interactions between virus host immune responses is crucial to preventing its lethal effects. expansion of myeloid‐derived suppressor cells (MDSCs) in COVID‐19, thereby suppressing responses, has been described as responsible for severity disease, but correlation MDSC subsets COVID‐19 elusive. Therefore, we classified patients according clinical laboratory findings—aiming...
Statins reduce cholesterol levels by inhibiting 3-hydroxy-3-methylglutaryl coenzyme A reductase and have a major place in the treatment of atherosclerotic disease. Recent studies shown anti-inflammatory properties statins. The purpose this study was to evaluate effect simvastatin on bleomycin (BLM)-induced pulmonary fibrosis rats. total 31 female Sprague-Dawley rats were divided into four groups: (1) intratracheal (IT) phosphate-buffered saline (PBS) + intraperitoneal (IP) PBS (n=7); (2) IT...
OBJECTİVES: The effectiveness of low-intensity pulmonary rehabilitation program applied patients with chronic obstructive disease (COPD) in terms exercise capacity, dyspnea scale, life quality and respiratory muscle strength. METHODS: study included 30 COPD. was 3 days a week, for 6 weeks period between December 1st 2012 August 31st 2013. Arterial blood gas (ABG), minute walking test (SMWT), function tests strength were evaluated before after treatment. St George's breathing questionnaire...
Background: Serum thymus and activation-regulated chemokine (TARC) periostin are reliable biomarkers in eosinophilic asthma. Objective: This study was carried out to determine the use of TARC as asthma compare superiority one over other, especially with an phenotype. Methods: The conducted 87 patients 42 healthy control subjects. Patients were also divided into non-eosinophilic phenotypes. A pulmonary function test performed all participants, serum induced sputum TARC, concentrations,...
Lymphopenia is the most important criterion of mortality and discharging feature for patients infected with coronavirus disease 2019 (COVID-19). This study aimed to investigate clinical impact a low molecular weight heparin (LMWH) treatment on course COVID-19.Patients’ symptoms, radiologic outcomes, hematologic, biochemical, D-dimer, C-reactive protein (CRP) results were obtained from their medical records. Participants separated into 2 groups: one was treated LMWH other not. Improvement in...
Flexible bronchoscopy (FB) is a procedure accepted to be safe in general, with low complication rates reported. On the other hand, it known that patients pre-existing respiratory failure have developed hypoventilation following FB. In this study effects of FB on muscle strength were investigated by measuring maximum pressures. One hundred and forty patients, aged between 25 90 years, who had undergone diagnostic February 2012 May 2012, recruited study. Pre- post-procedure maximal inspiratory...
Amaç: Bu çalışmada, kronik obstrüktif akciğer hastalığı (KOAH) alevlenmesinin en sık rastlanılan üç bakteriyel etkeni olan S. pneumoniae, H. influenzae ve M. catarrhalis'in gerçek zamanlı polimeraz zincir reaksiyonu (PCR) tekniği ile saptanması sonuçların kültür karşılaştırılması amaçlanmıştır.Yöntem: Çalışmaya KOAH alevlenmesi 62 hasta alındı
<title>Abstract</title> <bold>Background</bold> This study aimed to identify predictive factors for pulmonary fibrosis development in COVID-19 patients by analysing thorax CT (Computed tomography) findings, serum prolidase activity, MMP-1, MMP-7, TGF-β values, laboratory and demographic characteristics. <bold>Materials methods</bold> The investigation involved 68 patients, both male female, aged 18 years older, who were volunteers had been diagnosed with confirmed or possible COVID-19....
<title>Abstract</title> Chronic obstructive pulmonary disease (COPD) is a common respiratory condition characterised by persistent airflow limitation and frequent exacerbations. In patients with COPD exacerbations, whether steroid therapy should be administered via inhalation or the systemic route remains unclear. To address this, we aimed to evaluate response of sputum blood eosinophil counts inhaled steroids in hospitalised exacerbation.<bold> </bold>Our study included 58 at chest clinic...
Purpose/Aim: Idiopathic pulmonary fibrosis (IPF) is the most common idiopathic interstitial pneumonia. Multiple genetic factors, environmental exposures, micro-aspirations secondary to gastroesophageal reflux, age, sex, smoking habit, and infections contribute its etiology; consequently, pathogenesis remains unclear. The homeostasis of gut microbiota, including bacteria, archaea, fungi, can influence functions both intestine remote organs. There are still many unknowns regarding effects...