The aim of this study was to characterize the polyphenolic compounds and antioxidant activity cold-pressed seed oil from Finola cultivar industrial hemp (Cannabis sativa L.). Several methodologies have been employed evaluate in vitro hempseed (FHSO) both lipophilic (LF) hydrophilic fractions (HF). qualitative quantitative composition phenolic fraction FHSO performed by HPLC analyses. From results is evident that has high antioxidative activity, as measured DPPH radical (146.76 mmol TE/100 g...

Recently, there has been a growing interest in the recovery of agri-food waste within circular economy perspective. In this study, nutritional, phytochemical, and biological features cold-pressed hempseed oil (HSO) meal (HSM) two industrial hemp varieties (USO 31 Futura 75, THC ≤ 0.2%) were evaluated. The HSOs showed high total phenols flavonoid content, which confirmed by LC-DAD-ESI-MS analysis, with rutin as most abundant compound (56.93–77.89 µg/100 FW). They also proved to be rich source...

Abstract The most common type of osteoporosis is bone loss associated with ovarian hormone deficiency at menopause. There evidence that diets which contain high levels phytoestrogenic isoflavones are a low incidence and menopausal symptoms. Plant extracts, isoflavones, such as Red clover ( Trifolium pratense L.), have been used to reduce objective this study was evaluate the preventive effects total on progression induced by estrogens (ovariectomy) in rats. Bilateral ovariectomy performed...

Abstract Since ancient times, extracts of plants have been used for women's health to prevent menopausal symptoms. The symptoms menopause attributed a reduction in the amount estrogen produced by ovaries. In this study estrogenic activity commercial standardized extract roots Angelica sinensis , relieve climacteric was evaluated using vivo tests such as degree cornification vaginal epithelium, uterotrophic assays and serum LH concentration ovariectomized rats. Furthermore, effects on estrous...

The essential oil of Citrus aurantifolia (Christm) Swingle fruits (limes) was studied for its potential spasmolytic effects in relation to chemical composition. oil, extracted by hydrodistillation (HD), analyzed GC-FID and GC-MS. antispasmodic activity evaluated on isolated rabbit jejunum, aorta uterus. results indicated that the C possesses important properties, which are likely be due major constituents, limonene (58.4%), β-pinene (15.4%), γ-terpinene (8.5%), citral (4.4%).

The aim of study was to evaluate and compare the phytochemical profile, antioxidant antimicrobial properties two standardized extracts from non-psychotropic (Δ9 -tetrahydrocannabinol ≤0.2%) Cannabis sativa L. var. fibrante rich in cannabidiol (CBD). extracts, namely Fibrante Hexane Extract 1 (CFHE1) 2 (CFHE2), were obtained by extraction with acidified hexane dried flowering tops as such after hydrodistillation essential oil, respectively. Gas chromatographic analysis showed that...

Oxidative stress-induced neuronal cell death has been implicated in different neurological disorders and neurodegenerative diseases such as Alzheimer's disease Parkinson's. Using the disease-associated hydrogen peroxide (H(2)O(2)), we investigated neuroprotective efficacy of a natural mixture phytoestrogenic isoflavones (genistein, daidzein, biochanin A formononetin) from Trifolium pratense L. (Red clover) against oxidative human cortical line HCN 1-A maintained culture. Neuronal viability...

The juice of R. fruticosus (RFJ) fruits grown in Sicily was analysed for polyphenol compounds and tested to evaluate vitro antioxidant vivo antiinflammatory gastroprotective effects. RFJ, containing mainly anthocyanins, such as cyanidin derivatives, significant amounts phenolic acids, smaller flavonoids, showed activity DPPH (2,2‐diphenyl‐1‐picrylhydrazyl radical) (4,147.194 ± 17.199 mg trolox equivalent [TE]/100 ml), TE capacity (8,312.444 43.055 TE/100 ferric reducing power (2,177.830...

The purpose of this study was to evaluate the antioxidant and antimicrobial properties two extracts from a new Chinese accession (G‐309) Cannabis sativa L. (Δ 9 ‐tetrahydrocannabinol <0.2%) with high content propyl side chain phytocannabinoids. Dried flowering tops, as such after hydrodistillation essential oil, were extracted acidic hexane produce extract 1 (CChHE1) 2 (CChHE2), respectively. phytochemical profile CChHE1 CChHE2 investigated by gas chromatography–mass spectrometry (GC–MS)...

In this study, conventional and biological lemon cultivation techniques have been evaluated for their influence on the composition activity of essential oils extracted from fresh fruits. The were by hydrodistillation (HD) analyzed gas chromatography–flame ionization detector (GC-FID) GC–mass spectrometry (GC-MS). human Ishikawa cell line maintained in culture was used to test antiproliferative efficacy paper disc diffusion method employed determine antimicrobial activity. results obtained...

The aim of this study was to investigate the neuroprotective effects a titolated extract from Rhodiola rosea L. (RrE) and salidroside (Sa), one major biologically active compounds extracted medicinal plant, against oxidative stressor hydrogen peroxide (H 2 O ) glutamate (GLU)‐induced cell apoptosis in human cortical line (HCN 1‐A) maintained culture. results obtained indicate that exposure differentiated HCN 1‐A neurons GLU or H resulted concentration‐dependent death. A 24 h pre‐treatment...

Euphorbia dendroides L. is a rounded shrub commonly found in the Mediterranean area well-known, since ancient times, for its traditional use. The aim of present study was to investigate phytochemical profile as well antioxidant and anti-inflammatory properties flower (FE), leaf (LE), fruit (FrE), branch (BE) hydroalcoholic extracts. For this purpose, preliminary screening followed by RP-LC-DAD-ESI-MS analysis, several vitro cell-free colorimetric assays, were carried out. Moreover, toxicity...

Abstract Objectives This study investigated the relaxing effects of Valeriana officinalis L. (Valerianaceae) on human uterine muscle. The major uses this species in Europe are as a sedative and an anxiolytic; it is also used spasmolytic to treat gastrointestinal spasm. Methods We evaluated two valerian extracts (ethanolic aqueous) comparison with natural mixture valepotriates nifedipine spontaneous agonist-induced contractions non-pregnant myometrium vitro. Qualitative quantitative chemical...

Estrogens have a profound influence on skin. The relative hypoestrogenism that accompanies menopause exacerbates the deleterious effects of both intrinsic and environmental aging. improve skin in many ways. Among these, they increase collagen content, thickness moisture. There is evidence diets with high levels phytoestrogenic isoflavones are associated low incidence menopausal symptoms osteoporosis. Plant extracts such as red clover, which contain isoflavones, been used to reduce shown bone...

The aim of this study was to evaluate the antioxidant and anti-acetylcholinesterase properties phytochemical constituents latex from Euphorbia dendroides L. (Euphorbiaceae) growing wild in Sicily. Phytochemical analysis revealed that into E. triterpenoids were most abundant among identified compounds. Furthermore, a high content polyphenols mainly as phenolic acids, found. free-radical scavenging properties, by several vitro assays such DPPH, TEAC FRAP, have been evaluated. results showed...

The aim of this study was to compare the micro‐morphological features two different non‐drug Cannabis sativa L. biotypes (Chinese accession G‐309 and one fibrante variety) evaluate phytochemical profile as well some biological properties essential oils (EOs) obtained by hydrodistillation dried flowering tops. After a evaluation scanning electron microscopy, composition analysed GC–FID GC–MS analyses. Antioxidant anti‐acetylcholinesterase were investigated several in vitro cell‐free assays,...

Abstract In this communication we have examined the acute haemodynamic effects of two flavonoids with different electrophysiological characteristics, rhoifolin and vitexin, in anaesthetized dogs. The following parameters: mean aortic pressure, left ventricular systolic end‐diastolic its first derivative, arterial pulmonary capillary wedge right atrial pressure heart rate were measured. results obtained shown that vitexin caused a decrease rate. Differences performance index also noted.