A5101628769- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Wood Treatment and Properties
- Calcium Carbonate Crystallization and Inhibition
- Forest Biomass Utilization and Management
- Tree Root and Stability Studies
- Marine Biology and Environmental Chemistry
- Radioactive element chemistry and processing
- Polymer Surface Interaction Studies
- Nuclear Materials and Properties
- Electrospun Nanofibers in Biomedical Applications
- Acoustic Wave Phenomena Research
- Periodontal Regeneration and Treatments
- Bone and Dental Protein Studies
- Tissue Engineering and Regenerative Medicine
- Diatoms and Algae Research
- Forest ecology and management
- Surface Modification and Superhydrophobicity
- Dental Implant Techniques and Outcomes
- dental development and anomalies
- Supramolecular Self-Assembly in Materials
- Structural Engineering and Vibration Analysis
- Nanoplatforms for cancer theranostics
- Cephalopods and Marine Biology
- Additive Manufacturing and 3D Printing Technologies
University of Birmingham
2020-2022
Taipei Medical University
2020
The Edgbaston Hospital
2020
Yonsei University
2015-2019
Yonsei University College of Dentistry
2015-2019
University of Technology Sydney
2008-2019
University of Hong Kong
2012-2017
Prince Philip Dental Hospital
2012-2017
PLUS Foundation
2016
Chinese University of Hong Kong
2014-2016
Targeting and differentiating stem cells at sites of injury repair is an exciting promising area for disease treatment reparative medicine. We have investigated remote magnetic field activation nanoparticle-tagged mechanosensitive receptors on the cell membrane human bone marrow stromal (HBMSCs) use in osteoprogenitor delivery systems differentiation vitro vivo toward osteochondral lineage. HBMSC-labeled with beads coated antibodies or peptides to transmembrane ion channel stretch activated...
Porphyrin based photosensitizers are useful agents for photodynamic therapy (PDT) and fluorescence imaging of cancer. Porphyrins also excellent metal chelators forming highly stable metallo-complexes making them efficient delivery vehicles radioisotopes. Here we investigated the possibility incorporating (64)Cu into a porphyrin-peptide-folate (PPF) probe developed previously as folate receptor (FR) targeted fluorescent/PDT agent, evaluated potential turning resulting (64)Cu-PPF positron...
Identification of suitable scaffolds onto which human stem cells can be seeded to generate functional three-dimensional tissues is a major research goal. A natural marine sponge skeleton was selected as potential scaffold on the basis hydration fiber, presence open interconnected channels created by fiber network, collagenous composition and structural diversity architecture. The an undetermined species Spongia (Class Demospongiae: Order Dictyoceratida: Family Spongiidae), composed spongin,...
Nature has produced many intriguing and spectacular surfaces at the micro- nanoscales. These small surface decorations act for a singular or, in most cases, range of functions. The minute landscape found on lotus leaf is one such example, displaying antiwetting behavior low adhesion with foreign particulate matter. Indeed often been considered "benchmark" properties. One could expect that there are animal counterparts this self-drying self-cleaning system. In study, we show planthopper...
Abstract The external epithelial surfaces of plants and animals are frequently carpeted with small micro- nanostructures, which broadens their adaptive capabilities in challenging physical habitats. Hairs other shaped protuberances manage excessive water, light contaminants, predators or parasites innovative ways. We interested transferring these intricate architectures onto biomedical devices daily-life surfaces. Such a project requires very rapid accurate small-scale fabrication process...
Chirality is integral to biological complexity. Chiral biomolecules are central all fundamental recognition, conformational and replication functions in systems. also exists living cells higher order structures. Less known about the cellular interactions with chirality, although most imprinted chiral‐based signatures. The harnessing of molecular, supramolecular, structural chirality has been largely overlooked biomaterials chemistry engineering structures for regenerative medicine. Since a...
Despite progress in characterising natural surfaces, the applied use of architecture is still lacking use. We present superhydrophobic replicated surfaces as alternative approaches to antifouling paints.
A dental implant is used to replace a missing tooth. Fixing the in its natural position requires engineering of substantial amount conformal bone growth inside socket, osseointegration. However, this conventional attachment does not include periodontal ligament (PDL), which has fundamental role cushioning high mechanical loads. As result, tooth implants have shorter lifetime than and chance infections. We engineered "bio-implant" that provides living PDL connection for titanium implants. The...
Current control of pathogenic bacteria at all biomaterial interfaces is poorly attuned to a broad range disease-causing pathogens.
The aim of this study was to synthesize functional in vitro and vivo 3-dimensional (3D) constructs using a mix human mesenchymal populations articular chondrocytes encapsulated biomineralized polysaccharide templates. Single-cell–type or mixtures both cell types were alginate/chitosan cultured within rotating-bioreactor, perfused bioreactor system, static conditions for 28 days. Within single cell-type populations, type II collagen immunopositive cells present lacunae rotating-bioreactor...
This paper presents an overview of our recent studies on mineralized polysaccharide capsules and their potential as multifunctional scaffolds for the organisation delivery human cell types, DNA growth factors. Microcapsules containing these encapsulates are readily produced at room temperature in form alginate beads that stabilized by outer shell consisting ultra thin chitosan–calcium phosphate membrane. Modulation thickness composition influences rates release diffusion encapsulated cells,...
Background: A biotooth is defined as a complete living tooth, made in laboratory cultures from spontaneous interplay between epithelial and mesenchymal cell‐based frontal systems. good solution to these problems use induced pluripotent stem cells (iPSCs). However, no one has yet formulated culture conditions that effectively differentiate iPSCs into dental phenotypes analogous those present tooth development. Results: Here, we tried induce differentiation methods for (DEC) iPSCs. For the DEC...