A5038581285- Pressure Ulcer Prevention and Management
- Skin Protection and Aging
- Dermatology and Skin Diseases
- Advancements in Transdermal Drug Delivery
- RNA regulation and disease
- Wound Healing and Treatments
- Thermoregulation and physiological responses
- Contact Dermatitis and Allergies
- RNA Interference and Gene Delivery
- Pregnancy-related medical research
- Neonatal skin health care
- RNA Research and Splicing
- Ocular Surface and Contact Lens
- Neuroscience and Neuropharmacology Research
- Adipokines, Inflammation, and Metabolic Diseases
- Oral health in cancer treatment
- Insect and Pesticide Research
- Legionella and Acanthamoeba research
- interferon and immune responses
- Oral microbiology and periodontitis research
- Diagnosis and Treatment of Venous Diseases
- Medical and Biological Ozone Research
- Textile materials and evaluations
- Effects and risks of endocrine disrupting chemicals
- Exercise and Physiological Responses
University of Fukui
2020-2023
Kanazawa University
1992-2020
Kyoto Prefectural University of Medicine
2015-2016
With the increase in older populations, number of bedridden patients is becoming a matter concern. Skin microbiome and skin physiological functions are known to change according lifestyle community; however, such changes case movement- cleaning-restricted have not yet been revealed. To address this issue, we analyzed functions, including pH, hydration, sebum level, transepidermal water loss (TEWL), patients, compared with those ambulatory young individuals. For analysis, enrolled 19 healthy...
Background: Preventing recurrent pressure injuries (RPIs) is one of the important challenges faced in healthcare, but risk factors RPIs have not been fully revealed. This study aims to explore associated with RPIs, by focusing on skin physiology and its microbiome as local crucial for health healed tissue after injury healing. Methods: prospective observational was conducted a long-term care facility Japan patients whose PIs had within 1 month. Skin evaluated stratum corneum (SC) hydration,...
Objective: Prevention of recurrent pressure ulcers (PU) is one the most important challenges in wound care, furthermore, risk factors for PUs are still not fully understood. This study aimed to explore PU development within two weeks, including biophysical skin properties, pro-inflammatory cytokine (tumour necrosis factor [TNF]-α) levels and bacterial species, older patients. Method: prospective was conducted a long-term care facility with patients whose had healed months. Biophysical...
Abstract Serotonin 2C receptors (5‐ HT 2 C R s) are widely expressed in the central nervous system, and associated with various neurological disorders. 5‐ m RNA undergoes adenosine‐to‐inosine editing at five sites within its coding sequence, resulting expression of 24 different isoforms. Several edited isoforms show reduced activity, suggesting that modulates serotonergic systems brain causative relevance to neuropsychiatric Transgenic mice solely expressing non‐edited INI ‐isoform ( ) or...
A state of chronic inflammation, characterized by an increased level tumour necrosis factor-alpha (TNF-α), is often found in the obese population. The negative effects elevated TNF-α are not limited to systemic metabolism. It also reportedly affects skin integrity. Recently, relationship between obesity and fragility was reported; however, there has been little insight into how situ related severity obesity. In this study, we aimed measure on find detected skin.We used a novel, non-invasive...
For dry skin, the application of a hypoallergenic moisturizer twice daily is recommended in elderly individuals. However, it not known which most effective and appropriate among commercially available moisturizers.In this study, we aimed to investigate efficacy three widely used moisturizers for treatment senile skin. Patients/Methods. This interventional study involved individuals aged >65 years who were living nursing home. The participants randomly divided into (moisturizers A, B, C)...
Background/purpose Presently, skin‐cleaning agents that claim to be removed by water or wiping alone are commercially available and have been used for the purpose of bed baths. However, there is a lack knowledge on how washing differently affect skin physiological functions ceramide content. The aim this study was compare effects Methods Three kinds cleaning with different removal techniques (ie, wiping) were in study. Skin transepidermal loss, hydration, pH ) content measured before after...
Abstract Background/Purpose Previous studies have reported decreased dermal echogenicity and increased skin oxidative stress in overweight males. However, it is unknown whether these parameters of obese people are similar to those individuals exhibiting a normal body weight following loss. The purpose this study was (1) compare the changes structure levels before after loss Japan (2) clarify how aspects changed when would be reduced weight. Methods Male volunteers with mass index ≥25 kg/m 2...
Abstract Background/Purpose Skin care via moisturization compensates for the lack of skin barrier function. However, moisturizer application methods are not clearly decided. Here, we focused on and examined retention externally applied ceramide in stratum corneum ( SC ) using fluorescent imaging method. This study aimed to compare between normal dry an animal model. Methods Nine‐week‐old Sprague‐Dawley rats were divided into two groups: The model group was treated with acetone‐diethyl ether...
Abstract Purpose This study aimed to clarify the influence of different wiping methods on cleaning agent residue in hair follicles when using skin agents that are “removable‐by‐wiping.” Methods A total 18 male volunteers were recruited and a containing 10% fluorescein sodium salt (cleaning agent) was used this study. After gentle washing, removed via washing method (control) or three distinct (experiment). Hairs obtained from measurement area. The fluorescence intensities residual root bulb...
The sacral skin of bedridden older patients often develops a dysbiotic condition. To clarify whether the condition changes or is sustained over time, we analyzed microbiome and physiological functions in who completed our 2017 study.In 2019, collected on region measured hydration, pH, transepidermal water loss from 7 healthy young adults, 10 ambulatory 8 patients, all whom had been recruited for study. For analysis, 16S ribosomal RNA-based metagenomic analysis was used.No significant...
It has been reported that overweight Japanese males have poorly organised dermis and their skin may be fragile to external forces because of decreased dermal echogenicity. However, it is unknown whether the changes in structure actually affect function. The objective this study was clarify relationship between structural parameters functional obese males. A cross-sectional, observational conducted on male volunteers. Two ultrasound scanners, a 20-MHz Dermascan C® an 18-MHz MylabTM five® were...