A5058968257- Pressure Ulcer Prevention and Management
- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Dermatology and Skin Diseases
- Neonatal skin health care
- Esophageal and GI Pathology
- Dysphagia Assessment and Management
- Dermatologic Treatments and Research
- Advancements in Transdermal Drug Delivery
- Skin Protection and Aging
- Pelvic floor disorders treatments
- Hair Growth and Disorders
- Tracheal and airway disorders
- Child Nutrition and Feeding Issues
- melanin and skin pigmentation
- Surgical site infection prevention
- Allergic Rhinitis and Sensitization
- Bacterial biofilms and quorum sensing
- Laser Applications in Dentistry and Medicine
- Thermoregulation and physiological responses
- Tendon Structure and Treatment
- Contact Dermatitis and Allergies
- Oral health in cancer treatment
- Ocular Surface and Contact Lens
- Bee Products Chemical Analysis
The University of Tokyo
2014-2024
University of Tokyo Health Sciences
2023
University of Tokyo Hospital
2017
National Center for Global Health and Medicine
2017
Tokyo Women's Medical University
2017
Japan Society for the Promotion of Science
2015
University Health Care System
2014
Marymount University
2014
Abstract The identification of appropriate skin tear prevention guidelines for the elderly requires clinicians to focus on local risk factors such as structural alterations epidermis and dermis related tears. aim this cross‐sectional study is explore prevalence tears properties in Japanese patients at a long‐term medical facility. After doing study, 18 participants with without were recruited an evaluation their using 20‐ MHz ultrasonography, blotting also Corneometer CM ‐825, Skin‐...
A common complication in patients with incontinence is perineal skin lesions, which are recognized as a form of dermatitis. In these patients, exposed to digestive enzymes and intestinal bacterial flora, well excessive water. The relative contributions flora lesion formation have not been fully shown. This study was conducted reveal the process histopathological changes caused by proteases inoculation maceration. For maceration, agarose gel containing applied dorsal male Sprague-Dawley rats...
Objective: To identify the physiological and appearance characteristics of skin maceration caused by urine and/or faeces determine their suitability as risk indicators for incontinence-associated dermatitis. Method: This cross-sectional, comparative study involved sixty-nine elderly women with urinary faecal incontinence who provided informed consent to participate. Exclusion criteria included serious medical problems, acute illness presence damaged on buttocks. The macerated buttocks...
Abstract Undermined pressure ulcers ( PUs ) are troublesome complications that likely to delay wound healing. Early skin incision and debridement can prevent the deterioration of undermined , thus it is necessary identify devitalised tissue areas determine appropriate timing for such interventions. This retrospective cohort study evaluated whether a lower temperature at edge than bed periwound skin, detected by thermography, predict undermining development in 1 week after assessment....
The skin performs important structural and physiological functions, assessment represents an step in identifying problems. Although noninvasive techniques for assessing status exist, no such monitoring its are available. This study aimed to develop a novel skin-assessment technique known as blotting, based on the leakage of secreted proteins from inside following overhydration mice. applicability this was further investigated clinical setting.Skin blotting involves 2 steps: collecting by...
Pressure ulcers are characterized by chronicity, which results in delayed wound healing due to pressure. Early intervention for preventing pressure requires a prediction method. However, no study has reported the of Therefore, this focused on biological response-based molecular markers establishment an assessment technology predict We tested hypothesis that sustained compressive loading applied three dimensional cultured fibroblasts leads upregulation heat shock proteins (HSPs), CD44,...
Incontinence-associated dermatitis (IAD) is caused by prolonged exposure to urine/liquid stool. It a common and often painful skin condition in older incontinent adults because of poor prevention. Patients with urinary infections are at risk developing IAD, guide the development novel prevention strategies, we aimed develop an animal model IAD urine bacteria. First, contralateral sites on dorsal Sprague-Dawley rats were compromised sodium lauryl sulphate (SLS), simulating frequent cleansing...
In older adults, pressure injuries (PIs) are common and, despite advancements in PI care, associated with increased complications patients dementia for whom standardized treatments unavailable. Herein, we aimed to examine the influence of status on care practice pattern and healing outcomes discharge.
Wound biofilms delay healing of hard-to-heal wounds. Convenient biofilm identification tools for clinical settings are currently not available, hindering biofilm-based wound management. blotting with staining is a potential tool detection, owing to its convenience. Although predictive validity has been established, it necessary confirm concurrent validity. Furthermore, current systems employing ruthenium red have some disadvantages use. This study aimed evaluate the usability alcian blue as...
Abstract The decomposition of urea into ammonia by urease‐producing bacterium shows an elevation in the pH level, which can lead to incontinence‐associated dermatitis (IAD). This study aimed examine efficacy a combination antiseptic and urease inhibitor inhibiting Proteus mirabilis . We performed vitro assays compare effects inhibitor, only, untreated control with urea‐containing solution. Cultured P. was mixed solution, followed addition and/or inhibitor. main outcome used assess different...
One of the most common complications in patients with incontinence is incontinence‐associated dermatitis. This study aimed to examine influences lipidolytic enzymes and/or proteases on skin barrier and tissue structure development Two animal experiments, ex vivo , were performed using rats 3 factors (maceration, proteases, enzymes) alone or various combinations function histology skin. As a result, treatments, including both maceration application, caused erythrocyte leakage from blood...
Aging disrupts skin barrier function and induces xerosis accompanied by pruritus. In many cases, elderly patients complain of pruritus during hygiene care, a condition called aquagenic the (APE). To date, pathophysiology mechanism action APE have not been elucidated. We conducted present study to test hypothesis that hypo-osmotic shock epidermal cells inflammation elongation C-fibers nerve growth factor β (NGFβ) as basic APE. The dorsal HWY rats, which are model for disrupted function, was...
Alopecia impairs the physical and mental health of patients. We have previously shown that 8-week-old ob/ob mice no reactivity to depilation, which is a stimulus induces anagen transition in normal mice, while hair cycle abnormalities been reported other studies until reach 7 weeks age. Therefore, we hypothesized progression beyond examined 6- 24-week-old 10-week-old mice. After acclimation, dorsal skin was harvested phase identified histologically immunohistochemically. Normal showed...
Abstract Aim This clinical practice guideline aims to provide and recommend methods of assessing aspiration pharyngeal residue during eating swallowing selecting implementing nursing care for adults prevent the development pneumonia through early appropriate management oropharyngeal dysphagia. Methods In April 2018, Japan Academy Nursing Science established Supervisory Committee in Care Development/Standardization develop guidelines residual assessment care. was developed according Minds...
Tinea pedis (TP) may lead to the development of foot ulcers in diabetic patients; thus, its prevention patients is important. TP occurs after dermatophytes on skin scales attach feet. Therefore, it necessary remove and dermatophytes, this can be performed using various methods, including washing. This study aimed objectively examine association between presence foot-washing habits. We included 33 patients, and, these, 17 had TP. The washing residue feet was determined by applying a...
Clinicians often experience delayed epithelialization in diabetic patients, for which a high glucose condition is one of the causes. However, mechanisms underlying wound closure have not been fully elucidated, and effective treatments to enhance patients with hyperglycaemia established. Here we propose new reagent, acylated homoserine lactone (AHL), improve due disordered formation basement membrane epidermis hyperglycaemic rats. Acute was induced by streptozotocin injection this experiment....
Objective: Evaluating the bacterial bioburden of pressure ulcers through count and pathogenicity is important but currently difficult to perform in clinical setting. In order address this problem, we proposed two methods: 1) measurement using a quantitative device 2) detection biofilm formation by wound blotting. The purpose study was investigate relationship between bioburden, assessed combining these methods, presence inflammation. Patients participants cross-sectional were patients aged...
Abstract Asteatosis is common in elderly people due to a decrease the moisture content of epidermal stratum corneum through loss skin barrier function caused by aging. Because itching often accompanies asteatosis, this condition may cause quality life. Care staff care facilities have many opportunities provide for residents. In study, we examined how educational training on changed thoughts and actions these changes impacted conditions The subjects were all because work most closely with...
ABSTRACT Incontinence‐associated dermatitis (IAD) is one of the most serious complications in older people with incontinence. Controlling urine property absorbent pads could be effective for preventing IAD caused by bacterial urine. However, no animal model has been established to evaluate their effectiveness. This study aimed induce IAD‐like skin changes using containing and confirm pathophysiology rats. Hairless Wistar Yagi rats were divided into bacteria‐containing (BU) bacteria‐free (U)...