A5101497999- Cutaneous Melanoma Detection and Management
- Melanoma and MAPK Pathways
- Nonmelanoma Skin Cancer Studies
- Cutaneous lymphoproliferative disorders research
- Flowering Plant Growth and Cultivation
- Cell Image Analysis Techniques
- melanin and skin pigmentation
- Advanced Biosensing Techniques and Applications
- Skin Protection and Aging
- Cancer Genomics and Diagnostics
- Plant Physiology and Cultivation Studies
- Immunotherapy and Immune Responses
- Infectious Diseases and Mycology
- Cancer and Skin Lesions
- Multilevel Inverters and Converters
- AI in cancer detection
- Electric Motor Design and Analysis
- Growth and nutrition in plants
- Genetic and rare skin diseases.
- Light effects on plants
- CAR-T cell therapy research
- Optical Coherence Tomography Applications
- Plant responses to elevated CO2
- Advanced DC-DC Converters
- Plant and animal studies
United States Army Combat Capabilities Development Command
2024
General Dynamics (United States)
2024
United States Department of the Army
2024
The Alfred Hospital
2013-2023
Alfred Health
1997-2022
Monash University
1991-2021
Cancer Council Australia
2021
Armstrong Flight Research Center
1996-2020
Vall d'Hebron Hospital Universitari
2019
UNSW Sydney
2018
<h3>Objectives</h3> To investigate the spectrum of growth rates in melanomas and to identify clinical associations rapidly growing melanomas. <h3>Design</h3> Clinical interview, skin examination, pathology review. <h3>Setting</h3> Three tertiary melanoma referral centers 2 private dermatology practices. <h3>Patients</h3> A total 404 consecutive patients with invasive primary cutaneous <h3>Main Outcome Measure</h3> surrogate for rate was calculated as ratio Breslow thickness time development...
<h3>Objective</h3> To determine the incidence of new, changed, and regressed nevi melanomas in a cohort patients at high risk for melanoma using baseline total body photography dermatoscopy. <h3>Design</h3> Cohort study who underwent cutaneous between January 1, 1992, December 31, 1997, had least 1 follow-up visit by 1998. <h3>Setting</h3> Private practice rooms dermatologist conjunction with public hospital-based, multidisciplinary clinic Victoria, Australia. <h3>Patients</h3> A 309...
<h3>Objective</h3> To compare partial and excisional biopsy techniques in the accuracy of histopathologic diagnosis microstaging cutaneous melanoma. <h3>Design</h3> Prospective case series. <h3>Setting</h3> Tertiary referral, ambulatory care, institutional practice. <h3>Patients</h3> Consecutive cases from 1995 to 2006. <h3>Interventions</h3> Partial biopsy. Other factors considered were anatomic site, physician type at initial management, hypomelanosis, melanoma subtype, sample size,...
KELLY, JOHN W. M.B.B.S., F.A.C.D.; SAGEBIEL, RICHARD M.D.; CALDERON, WILFREDO MURILLO, LUIS DAKIN, L. BLOIS, MARSDEN S. PH.D., M.D.Author Information
Abstract Purpose: The mutation load in melanoma is generally high compared with other tumor types due to extensive UV damage. Translation of exome sequencing data into clinically relevant information therefore challenging. This study sought characterize mutations identified primary cutaneous melanomas and correlate these clinicopathologic features. Experimental Design: DNA was extracted from 34 fresh-frozen matched peripheral blood. Tumor histopathology reviewed by two dermatopathologists....
Nodular melanoma (NM) is a rapidly progressing potentially lethal skin tumor for which early diagnosis critical.To determine the dermoscopy features of NM.Eighty-three cases NM, 134 invasive non-NM, 115 nodular benign melanocytic tumors, and 135 nonmelanocytic tumors were scored using modified previously described methods. Lesions separated into amelanotic/hypomelanotic or pigmented to assess outcomes.Predominantly hospital-based clinics from 5 continents.Sensitivity, specificity, odds...
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Objectives (1) To assess the incidence of melanoma in a cohort patients with dysplastic melanocytic naevi (DMN) and relationships between Incident melanomas preexisting risk numbers DMN. (2) examine role patient versus physician In detecting relative value surveillance prophylactic excision. Design Prospective study. Patients setting Two hundred seventy-eight adults, each five or more DMN, were followed up for mean period 42 months private dermatology practice. DMN clinically diagnosed....
Синтез алгоритма векторной широтно-импульсной модуляции в девятифазном активном выпрямителе напряжения
<h3>Objectives</h3> To explore the clinical associations of thick melanoma and to compare clinicopathological variables nodular superficial spreading types. <h3>Design</h3> Cross-sectional study all invasive primary melanomas recorded by Victorian Cancer Registry for 1998 those reviewed Melanoma Service between October 1, 1994, April 31, 1999. <h3>Setting</h3> Population-based cancer registry public hospital–based multidisciplinary clinic. <h3>Patients</h3> This included 1422 patients 674...
A total of 844 cutaneous malignant melanomas were examined prospectively for the presence or absence histologic regression within primary tumor. Cases then stratified into three groups according to tumor thickness and survival was compared between substrata with without in each group. The distribution other major prognostic variables these assessed their influence as potential confounding considered. No statistically significant effect on found any strata. These results do not confirm...
To assess 4 dermoscopy methods in a nonexpert setting.Sixty-one medical practitioners, mainly primary care physicians Australia, were trained algorithms. Participants then assessed macroscopic and dermoscopic images of 40 melanocytic skin lesions. Each the was with pattern analysis, 7-point checklist, ABCD rule, Menzies method.The method showed highest sensitivity, 84.6%, for diagnosis melanoma, followed by checklist (81.4%), rule (77.5%), analysis (68.4%), assessment image (60.9%). Pattern...
In melanoma, mutations in KIT are most frequent acral and mucosal subtypes rarely reported cutaneous melanomas particularly those associated with intermittent UV exposure. Conversely arising within chronic sun damaged skin considered to harbour at higher rates. To characterize the frequency of a representative melanoma population, 261 patients from two Australian centres were prospectively screened for exons 11, 13 17 gene. A total 257 had non-acral sites four melanomas. No or ocular...
Pole-phase modulation adjusts the pole-phase ratio of an induction machine and requires a multileg, multiphase inverter. This paper analyzes n-leg n-phase inverter presents techniques for space vector pulse width (SVPWM). In particular, nine-phase SVPWM is developed implemented on nine-winding machine. The compared to sine-triangle PWM in terms dc bus utilization.
The role of light quality and quantity in regulating growth vegetative Dendranthema × grandiflorum (Ramat.) Kitamura was evaluated using CuSO 4 solutions water (control) as spectral filters. Copper sulfate filters increased the red (R): far-red (FR) blue (B): R ratios (R = 600 to 700 nm; FR 800 B 400 500 urn) transmitted light. Photosynthetic photon flux (PPF) under 4%, 8% 16% reduced 26%, 36%, 47%, respectively, from natural irradiance greenhouse, which averaged ≈ 950 μmol·m -2 ·s -1 ....
<h3>Background</h3> Nodular melanoma (NM), representing 15% to 30% of all melanomas, constitutes nearly half melanomas thicker than 2 mm. frequently lacks clinical features seen in other subtypes and has a faster growth rate. We reviewed series cases NM that was less 1.3 mm thick identify historical, clinical, dermoscopic factors may facilitate earlier diagnosis NM, with the hope reducing its associated morbidity mortality. <h3>Observations</h3> The thin lesions we analyzed had rather subtle...
Mitotic rate is now recognized as having independent prognostic significance in melanoma survival. However, its clinicopathologic associations have not been the focus of any previous study.To identify a set patient and tumor characteristics associated with high-mitotic-rate aim facilitating earlier detection aggressive primary invasive melanoma.Cross-sectional study patients from multidisciplinary clinic based public hospital. A total 2397 cases January 2006 to December 2011 were reviewed by...
Merkel cell carcinoma (MCC) is an aggressive cutaneous malignancy with a high mortality rate. Diagnosis often delayed.To characterize the dermoscopic features of MCC.Clinical and images 12 biopsy-proven MCCs were analysed in retrospective manner, existing criteria being scored independently by three dermatologists.The four most frequent clinical cherry red colour, shiny surface, sharp circumscription nodular morphology. Significant included linear irregular polymorphous vessels, poorly...