A5103123117- Anaerobic Digestion and Biogas Production
- interferon and immune responses
- Wastewater Treatment and Nitrogen Removal
- Microbial Fuel Cells and Bioremediation
- Biofuel production and bioconversion
- Immune Response and Inflammation
- Membrane Separation Technologies
- Tryptophan and brain disorders
- Advanced Sensor and Control Systems
- Chromium effects and bioremediation
- Herpesvirus Infections and Treatments
- PI3K/AKT/mTOR signaling in cancer
- Inflammasome and immune disorders
- Food composition and properties
- Wastewater Treatment and Reuse
- Food Waste Reduction and Sustainability
- Phenothiazines and Benzothiazines Synthesis and Activities
- Municipal Solid Waste Management
- Bacterial Genetics and Biotechnology
- Enzyme Production and Characterization
- Food Quality and Safety Studies
- Liver physiology and pathology
- Methane Hydrates and Related Phenomena
- Microbial Metabolic Engineering and Bioproduction
- NF-κB Signaling Pathways
Shanghai Institute of Pollution Control and Ecological Security
2020-2025
Tongji University
2018-2025
State Key Laboratory of Pollution Control and Resource Reuse
2018-2025
Huazhong Agricultural University
2014-2023
Center of Hubei Cooperative Innovation for Emissions Trading System
2021
Shenyang Pharmaceutical University
2016-2018
Shanghai Institute of Technology
2018
Wuxi Municipal Product Quality Supervision and Inspection Institute
2012-2013
Abstract The members of tripartite-motif containing (TRIM) protein participate in various cellular processes and play an important role host antiviral function. TRIM proteins exert their activity either directly by degrading viral through E3 ligase activity, or indirectly promoting innate immunity. This study demonstrated for the first time that TRIM52 is a novel against Japanese encephalitis virus (JEV) infection. Overexpression restricted JEV replication BHK-21 293T cells. In addition,...
The transcription factor NF-κB plays an important role in modulation of inflammatory pathways, which are associated with diseases, neurodegeneration, apoptosis, immune responses, and cancer. Increasing evidence indicates that TRIM proteins crucial the regulation signaling pathways. In this study, we identified TRIM67 as a negative regulator TNFα-triggered activation. Ectopic expression significantly represses TNFα-induced activation pro-inflammatory cytokines TNFα IL-6. contrast, Trim67...
Many phages, such as T4, protect their genomes against the nucleases of bacterial restriction-modification (R-M) and CRISPR-Cas systems through covalent modification genomes. Recent studies have revealed many novel nuclease-containing antiphage systems, raising question role phage genome modifications in countering these systems. Here, by focusing on T4 its host Escherichia coli, we depicted landscape new E. coli demonstrated roles Our analysis identified at least 17 defense with type III...
In this study, quality of Man-tou, the Chinese traditional steamed bread during storage was studied. Values for water retention capacity, total solubles, soluble starch, and amylose amylopectin Man-tou decreased with time. Results showed that hardness, chewiness gumminess increased, while, springiness cohesiveness resilience along prolonged time (p<0.05). Sensory evaluation results all sensory rating including softness, stickiness, cohesiveness, elasticity, taste score, dropped...
Human d-amino acid oxidase (h-DAAO) can effectively act on d-serine, which has been actively explored as a novel therapeutic target for treating schizophrenia. In this study, 37 h-DAAO inhibitors based 6-hydroxy-1,2,4-triazine-3,5(2H,4H)-dione scaffold were obtained to construct the optimal comparative molecular field analysis (CoMFA, q2 = 0.613, r2 0.966) and similarity index (CoMSIA, 0.669, 0.985) models. The results indicate that models have good predictability strong stability....
Influenza virus NS2 is well known for its role in vRNP (viral RNP) nuclear export; however, function has not been fully understood. A recent study showed that might interact with HIST1H1C (H1C, H1.2). Histones have found to affect influenza replication, such as the H2A, H2B, H3 and H4, but H1 detected. Here, we H1C interacts via C-terminal nucleus affects replication. The H1N1 replicates better knockout A549 cells compared wild-type cells, primarily because of regulation on IFN-β. Further...
Japanese encephalitis virus (JEV) is one of the pathogens that can invade central nervous system, causing acute infection and inflammation brain. SOCS3 protein plays a vital role in immune processes system. In this study, Raw264.7 cells suckling mice were infected with JEV, expression was analyzed by gene profile, semiquantitative RT-PCR, qRT-PCR, immunohistochemistry (IHC) Western blot. Results indicated 520 genes found to be differentially expressed (fold change ≥ 2.0, p < 0.05) total....