- Dietary Effects on Health
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- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
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Albert Einstein College of Medicine
2013-2024
Montefiore Medical Center
2017-2024
Yeshiva University
2023
The Bronx Defenders
1976-2021
Although fasting is increasingly applied for disease prevention and treatment, consensus on terminology lacking. Using Delphi methodology, an international, multidisciplinary panel of researchers clinicians standardized definitions various approaches in humans. Five online surveys a live conference were conducted with 38 experts, 25 whom completed all 5 surveys. Consensus was achieved the following terms: "fasting" (voluntary abstinence from some or foods beverages), "modified fasting"...
Intermittent fasting is increasing in popularity as a means of losing weight and controlling chronic illness. Patients with diabetes mellitus, both types 1 2, comprise about 10% the population United States would likely be attracted to follow one many methods intermittent fasting. Studies on safety benefits are very limited though, health recommendations unfortunately today arise primarily from loss gurus animal studies. Medical guidelines how manage therapeutic patients non-existent. The...
This Viewpoint summarizes evidence about the effects of intermittent fasting on chronic disease markers and considers potential concerns as a strategy for weight management glycemic control in people with type 2 diabetes.
Editor’s comment : The commentary by Dr. Grajower has such important clinical relevance that responses were invited from the three pharmaceutical companies supply insulin in U.S. and American Diabetes Association, all of these combined this commentary. commenting letter individual authored separately are completely independent each other. Diabetic patients treated with insulin, whether for type 1 or 2 diabetes, prone to often unexplained swings their blood glucose. These can vary...
We have observed six episodes of severe symptomatic hypoglycemia in 5 nondiabetic patients on chronic maintenance hemodialysis. The common factor all was propranolol administration for the treatment hypertension. This observation suggests that β-adrenergic blockade may cause profound dialyzed with other predisposing factors such as poor nutrition, liver dysfunction or stress. On basis our experience, we recommend blood sugar determinations propranolol-treated during dialysis against...
The concentration of hepatic nuclear T3 receptors was measured in isolated nuclei from athyreotic mice bearing thyrotrophic tumors and intact rats with Walker 256 carcinoma. Receptor reduced all tumor-bearing animals. mean receptor capacity the [0.31 +/- 0.05 (SEM) ng/mg DNA] significantly decreased simultaneously assayed controls (0.47 0.04 DNA; P less than 0.01). No change apparent equilibrium association constant observed. In individual rats, magnitude decrease highly correlated...
The activity of hepatic α-glycerophosphate dehydrogenase (α-GPD) and malic enzyme (ME) was measured in rats bearing the Walker 256 carcinoma to assess relationship between reduction nuclear L-T3 (T3) receptor concentration which occurs tumor-bearing (T) biological effects thyroid hormones. T3 uniformly decreased when tumors exceeded 9.5% body weight. No change basal α-GPD observed, but ME 29–61% control. decrease did not appear be related T;) since also T with that were too small effect a...
Most deaths from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection occur in older subjects. We assessed the utility of serum inflammatory markers interleukin-6 (IL-6), C reactive protein (CRP), and ferritin (Roche, Indianapolis, IN), SARS-CoV-2 immunoglobulin G (IgG), M (IgM), neutralizing antibodies (Diazyme, Poway, CA). In controls, non-hospitalized subjects, hospitalized subjects for RNA (n = 278), median IgG levels arbitrary units (AU)/mL were 0.05 negative 14.83...
This commentary constitutes the opinions of endocrinologists whose names are appended. The is based on articles published in peer-reviewed journals as listed cited references, well cumulative experience treating patients with type 1 diabetes mellitus (T1DM). applies only to T1DM, and does not apply 2 DM who being treated insulin even though principles may be similar. recommendations outlined also do NOT pregnant woman should fast. Additionally, this preclude an individual from directing any...
Although fasting is increasingly applied to disease prevention and treatment, consensus on terminology lacking. Using Delphi methodology, an international, multidisciplinary panel of researchers clinicians standardized definitions various approaches. Five online surveys a live conference were conducted with 38 experts, 25 whom completed all five [Europe (n=12), North America Australia (n=1)]. Consensus was achieved for the terms: "fasting" (voluntary abstinence from some or foods beverages),...
Patients with diabetes may undergo an approximately 24-h fast for a voluntary religious observance or in preparation medical procedure. Commonly, patients will manage their before and during such fasting without guidelines from doctors, often because they did not ask advice. The physician should therefore take the lead advising how to safely, order avoid situation wherein patient manages medication changes on his/her own. Furthermore, it sends message that having does preclude living...