Israel Núñez-Tapia

ORCID: 0000-0003-0733-9368
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Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • Advanced Cellulose Research Studies
  • Collagen: Extraction and Characterization
  • Surface Modification and Superhydrophobicity
  • Aerogels and thermal insulation
  • Advanced Polymer Synthesis and Characterization
  • Polymer Nanocomposite Synthesis and Irradiation
  • Wound Healing and Treatments
  • Protein Hydrolysis and Bioactive Peptides
  • 3D Printing in Biomedical Research
  • Essential Oils and Antimicrobial Activity
  • Antimicrobial agents and applications
  • Hydrogels: synthesis, properties, applications
  • HER2/EGFR in Cancer Research
  • Bacterial biofilms and quorum sensing
  • Silk-based biomaterials and applications
  • Mesenchymal stem cell research
  • Nanoplatforms for cancer theranostics
  • Tissue Engineering and Regenerative Medicine
  • Marine Biology and Environmental Chemistry
  • Colorectal Cancer Treatments and Studies
  • Gastric Cancer Management and Outcomes
  • Innovative Microfluidic and Catalytic Techniques Innovation

Universidad Nacional Autónoma de México
2023-2025

Instituto de Investigaciones en Ciencia y Tecnología de Materiales
2024

The University of Texas Health Science Center at San Antonio
2024

Mesenchymal stem cells (MSCs) hold significant potential in regenerative medicine, tissue engineering, and cultivated meat production. However, large-scale MSC production is limited by their need for surface adherence during growth. This study evaluates two biocompatible materials—collagen-coated alginate microcarriers polylactic-co-glycolic acid (PLGA) nanofibers—as novel growth substrates to enhance proliferation. Physicochemical characterization confirmed successful collagen integration...

10.3390/biom15030345 article EN cc-by Biomolecules 2025-02-27

Staphylococcus aureus biofilms are particularly challenging to eradicate due their protective niche, which increases bacterial resistance. This has encouraged the scientific community explore new perspectives of control. Polymeric nanotechnology and use natural compounds have been emerging as promising tools for treating antimicrobial resistance preventing because nanosize permits disruption biofilms, reducing dose decreasing biomolecules’ limitations such high volatility low solubility,...

10.1155/jnt/4522031 article EN cc-by Journal of Nanotechnology 2025-01-01

Liver disease causes approximately 1.75 million deaths per year and chronic liver (CLD) is usually detected in advanced stages (cirrhosis or hepatocellular carcinoma) that require partial ablation transplant. STAT-3 has been identified as a therapeutic target cancer. Moreover, collagen matrix scaffolds (CMS) can be used carriers of antineoplastic drugs for carcinoma. The objective was to determine the capacity CMS vehicle WP1066 (inhibitor STAT3) an vitro HCC model. incubated with cell lines...

10.1016/j.aohep.2024.101403 article EN cc-by-nc-nd Annals of Hepatology 2024-02-01

Abstract The incorporation of inorganic nanoparticles (NP) into nanofibrous polymeric membranes (NPM) is an attractive approach to developing multifunctional nanocomposites. purpose this study was incorporate titanium dioxide (TiO 2 ) NP NPM enhance the overall properties. Polycaprolactone (PCL) with TiO -NP (0.2 wt%) fabricated by means Air-Jet Spinning (AJS) technique. physicochemical characterization PCL-TiO -NPM performed X-ray powder diffraction (XRD), morphology observed under scanning...

10.1007/s44174-023-00148-y article EN cc-by Deleted Journal 2024-01-16

Abstract This study investigates the extraction and characterisation of collagen derived from fish skin scales, collagens obtained were used to produce membranes which subsequently cross-linked by EDC/NHS. A comprehensive investigation their microstructure, composition, mechanical properties, swelling, degradation, thermal properties a 24 h cell viability test was carried out. The results showed that yields scales 25.14 ± 2.90 29.26 2.53%, respectively. Mechanical stress tests made...

10.1007/s44174-024-00233-w article EN cc-by Deleted Journal 2024-09-16

This study presents an innovative and scientifically accessible approach for formulating polymeric nanoparticles containing essential oils, readily available in Mexico, to bridge the gap between traditional conventional medicine. The primary objective is address growing challenge posed by drug-resistant microorganisms. Specifically, we focus on harnessing antimicrobial potential of Oregano Rosemary along with their key phytochemical constituents, Carvacrol p-cymene, respectively. While these...

10.1016/j.jbc.2024.106065 article EN cc-by Journal of Biological Chemistry 2024-03-01

La ingeniería de tejidos busca desarrollar andamios funcionales que restauren o mantengan la función y órganos dañados. Para ello, emplea biomateriales, células moléculas bioactivas. Sus aplicaciones van más allá regeneración, abarcando liberación fármacos, biosensores pruebas toxicidad. Una estrategia clave es descelularización recelularización órganos, así como el uso materiales naturales sintéticos pueden ser combinados modificados químicamente. Diversos métodos, liofilización...

10.22201/iim.rma.2024.40.33 article ES 2024-02-15

Introduction: One of the most attractive fields for cellulose aerogels is water remediation, basically in pollutant’s adsorption and oil/water separation. There are different sources to extract cellulose, but extraction from paper waste an excellent option impulse circular materials applications. Methods: We obtained office through a simple alkali method used it fabricate aerogel by freeze-drying based on materials’ circularity. To increase lipophilicity, was modified using two coatings:...

10.3389/fmats.2023.1308094 article EN cc-by Frontiers in Materials 2023-12-14
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