Rocío Alejandra Chávez-Santoscoy

ORCID: 0000-0002-4551-1862
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Nanoparticles: synthesis and applications
  • Food composition and properties
  • Natural Antidiabetic Agents Studies
  • Cholesterol and Lipid Metabolism
  • Microencapsulation and Drying Processes
  • Essential Oils and Antimicrobial Activity
  • Botanical Research and Applications
  • Seed and Plant Biochemistry
  • Microbial Metabolites in Food Biotechnology
  • Bee Products Chemical Analysis
  • Pituitary Gland Disorders and Treatments
  • Medicinal Plants and Neuroprotection
  • Natural Products and Biological Research
  • Probiotics and Fermented Foods
  • Lipid metabolism and biosynthesis
  • Algal biology and biofuel production
  • Biochemical Analysis and Sensing Techniques
  • Selenium in Biological Systems
  • Electrospun Nanofibers in Biomedical Applications
  • Mesenchymal stem cell research
  • Protein Hydrolysis and Bioactive Peptides
  • Proteins in Food Systems
  • Agriculture Sustainability and Environmental Impact
  • Neuroblastoma Research and Treatments

Tecnológico de Monterrey
2009-2025

Universidad Autónoma de Baja California
2015-2020

A diet rich in polyphenols can ameliorate some metabolic alterations associated with obesity and type 2 diabetes. Opuntia ficus-indica (OFI) is a plant isorhamnetin glycosides highly consumed Mexico. The purpose of this research was to determine the effect an OFI extract on mouse model diet-induced isolated pancreatic islets. added high fat (HF) at low (0.3%) or (0.6%) dose administered C57BL/6 mice for 12 weeks. Mice fed HF supplemented gained less body weight exhibited significantly lower...

10.1039/c4fo01092b article EN Food & Function 2014-12-16

Black bean ( Phaseolus vulgaris L.) seed coats are a rich source of natural compounds with potential beneficial effects on human health. Beans exert hypolipidaemic activity; however, this effect has not been attributed to any particular component, and the underlying mechanisms action protein targets remain unknown. The aim present study was identify quantify primary saponins flavonoids extracted from black coats, their lipid metabolism in rat hepatocytes C57BL/6 mice. methanol extract...

10.1017/s0007114514001536 article EN British Journal Of Nutrition 2014-07-24

The wide application of silver nanoparticles (AgNPs) has pointed out the need to evaluate their potential risk and toxic effects on human health. Herein, cytotoxic Argovit™ AgNPs were evaluated eight cancer cell lines. Further studies performed in gynecological lines from cervical (HeLa) breast (MDA-MB-231 MCF7) cancer. In both cases, half maximal inhibitory concentration (IC 50 ) produced formation reactive oxygen species (ROS) after 24 h incubation, but it was not statistically significant...

10.1177/0960327116675206 article EN Human & Experimental Toxicology 2016-11-04

Hormesis is considered a dose-response phenomenon characterized by growth stimulation at low doses and inhibition high doses. The hormetic response silver nanoparticles (AgNPs) on in vitro multiplication of sugarcane was evaluated using temporary immersion system.Sugarcane shoots were used as explants cultured Murashige Skoog medium with AgNPs concentrations 0, 25, 50, 100, 200 mg/L. Shoot rate length to determine response. Total content phenolic compounds sugarcane, mineral nutrition,...

10.1177/1559325817744945 article EN cc-by-nc Dose-Response 2017-10-01

In recent years, the incidence of atherosclerotic cardiovascular disease, obesity, and diabetes has increased largely worldwide. present work, we evaluated genoprotective effect consumption flavonoids-rich chocolate on 84 young volunteers. Biochemical indicators related to prevention treatment risk metabolic syndrome were also determined. A randomized, placebo-controlled, double-blind study was performed in Autonomous University Baja California. The treatments comprised daily either 2 g dark...

10.3390/molecules23092220 article EN cc-by Molecules 2018-09-01

Mesenchymal stem cells (MSCs) hold significant potential in regenerative medicine, tissue engineering, and cultivated meat production. However, large-scale MSC production is limited by their need for surface adherence during growth. This study evaluates two biocompatible materials—collagen-coated alginate microcarriers polylactic-co-glycolic acid (PLGA) nanofibers—as novel growth substrates to enhance proliferation. Physicochemical characterization confirmed successful collagen integration...

10.3390/biom15030345 article EN cc-by Biomolecules 2025-02-27

Abstract For the first time, complete genome assembly of dolphinfish (Coryphaena hippurus), a tropical cosmopolitan species with commercial fishing importance was sequenced. Using combination Illumina and Nanopore sequencing technologies, draft 497.8 Mb assembled into 6,044 contigs, an N50 200.9 kb BUSCO completeness score 89%. This high-quality provides valuable resource to study adaptive evolutionary processes supports conservation management strategies for this ecologically economically...

10.1093/g3journal/jkaf059 article EN cc-by G3 Genes Genomes Genetics 2025-03-19

Familial partial lipodystrophy type 2 is a rare disease, particularly when it caused by nonclassical gene variants. A high index of suspicion essential for timely diagnosis. We present the case 32-year-old woman, referred to evaluation possible Cushing syndrome, which was clinically and biochemically ruled out. Yet, due finding rather abnormal fat distribution during physical examination, diagnosis cogitated. Whole-exome sequencing revealed missense variant exon 11 R582H encoding Laminin...

10.20945/2359-4292-2024-0293 article EN PubMed 2025-03-24

Due to their antibacterial and antiviral effects, silver nanoparticles (AgNP) are one of the most widely used nanomaterials worldwide in various industries, e.g., textiles, cosmetics biomedical-related products. Unfortunately, lack complete physicochemical characterization variety models evaluate its cytotoxic/genotoxic effect make comparison decision-making regarding safe use difficult. In this work, we present a systematic study cytotoxic genotoxic activity commercially available AgNPs...

10.3390/nano10071386 article EN cc-by Nanomaterials 2020-07-16

Bread is among the three top foods that provide most of dietary selenium (Se) for world population. Selenomethionine present in flour and bread major organic moiety (>65%). The Se concentration assayed wheat kernels mainly affected by agronomic factors such as soil fertility. dry milling to produce refined technology leavened breads also greatly affect bioavailability. supranutritional intakes inorganic have long been linked prevention cancer, oxidative stress, cardiovascular diseases....

10.1094/cchem-05-14-0110-rw article EN Cereal Chemistry 2014-10-01

Quercetin is a bioactive component that capable of having therapeutic potential in the prevention different noncommunicable chronic diseases (NCDs). However, it presents instability gastrointestinal tract addition to low bioavailability. One way overcome limitations quercetin lies using nanotechnology for development nanoparticles, based on biopolymers, are being ingestible. Inulin, fructan-type polysaccharide, acts as delivery system release target cell, guaranteeing stability molecule....

10.3390/pharmaceutics14050888 article EN cc-by Pharmaceutics 2022-04-19

Probiotics have gained significant attention in recent years due to the growing awareness of physical health and well-being. However, maintaining high concentrations probiotics throughout product's shelf life during gastrointestinal tract is crucial for ensuring their health-promoting effects. After determining an optimal formulation through a fractional factorial model, this study optimizes probiotic Bacillus Clausii delivery spray-drying microencapsulation using novel...

10.1016/j.heliyon.2024.e24923 article EN cc-by-nc-nd Heliyon 2024-01-01

(-)-Epicatechin and quercetin have attracted considerable attention for their potential therapeutic application in non-communicable chronic diseases. A novel hybrid inulin-soy protein nanoparticle formulation was simultaneously loaded with (-)-epicatechin (NEQs) to improve the bioavailability of these flavonoids human body, NEQs were synthesized by spray drying. After process optimization, physicochemical functional properties characterized including vitro release, gastrointestinal...

10.3390/nano13101615 article EN cc-by Nanomaterials 2023-05-11
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