- Pituitary Gland Disorders and Treatments
- Bacteriophages and microbial interactions
- Neuroblastoma Research and Treatments
- Biochemical and Structural Characterization
- Antimicrobial Peptides and Activities
- Vector-borne infectious diseases
- Growth Hormone and Insulin-like Growth Factors
- Neurobiology and Insect Physiology Research
- Mesenchymal stem cell research
- Botanical Research and Chemistry
- Genetic factors in colorectal cancer
- Enzyme Catalysis and Immobilization
- Immune cells in cancer
- Neuroendocrine Tumor Research Advances
- Protein Hydrolysis and Bioactive Peptides
- Genetic and Environmental Crop Studies
- Agricultural and Food Production Studies
- Aquaculture disease management and microbiota
- Connective tissue disorders research
- vaccines and immunoinformatics approaches
- Glioma Diagnosis and Treatment
- Bone and Dental Protein Studies
- Aquaculture Nutrition and Growth
- Glycosylation and Glycoproteins Research
- Bee Products Chemical Analysis
Tecnológico de Monterrey
2018-2025
Instituto Nacional de Ciencias Agrícolas
2011
Abstract For the first time, complete genome assembly of dolphinfish (Coryphaena hippurus), a tropical cosmopolitan species with commercial fishing importance was sequenced. Using combination Illumina and Nanopore sequencing technologies, draft 497.8 Mb assembled into 6,044 contigs, an N50 200.9 kb BUSCO completeness score 89%. This high-quality provides valuable resource to study adaptive evolutionary processes supports conservation management strategies for this ecologically economically...
Familial partial lipodystrophy type 2 is a rare disease, particularly when it caused by nonclassical gene variants. A high index of suspicion essential for timely diagnosis. We present the case 32-year-old woman, referred to evaluation possible Cushing syndrome, which was clinically and biochemically ruled out. Yet, due finding rather abnormal fat distribution during physical examination, diagnosis cogitated. Whole-exome sequencing revealed missense variant exon 11 R582H encoding Laminin...
Microalgae species are sustainable sources for diverse bioactive compounds of commercial interest. Within the framework bioeconomy, exopolysaccharides (EPS) from microalgal stand out as potential high-value molecules in cosmetic, nutraceutical, and pharmaceutical industries. Since goal is to increase EPS presence those markets, prospecting applications through characterization species–structure–bioactivity relations optimizing production yields economically feasible strategies needed. This...
Totoaba macdonaldi is an endemic, vulnerable, carnivorous fish of the Gulf California that currently being cultivated in northwestern Mexico for commercial and conservation purposes. The challenge aquaculture finding a diet meets protein requirements at acceptable price does not compromise its overall performance. Current diets are either prejudicial environment or have caused adverse effects on digestive system liver Totoaba. To counteract those negative effects, this study evaluates...
No genetic basis is currently established that differentiates hypermobility spectrum disorders (HSD) from hypermobile Ehlers–Danlos syndrome (hEDS). Diagnosis entirely based on clinical parameters with high overlap, leading to frequent misdiagnosis of these two phenotypes. This study presents a landscape DNA mutations through whole-exome sequencing patients clinically diagnosed generalized HSD. In this study, three genes (MUC3A, RHBG, and ZNF717) were mutated in all five evaluated. The...
Cattle tick (Rhipicephalus microplus) represents a severe problem causing substantial economic losses, estimated in billions of dollars annually. Currently, chemical acaricides represent the most widely used control method. However, several problems such as resistance have been described. Phage-based vaccines fast and low-cost tool for antigen delivery. In this regard, objective present work was to develop candidate phage-based vaccine displaying cattle (Bm86-derived Sbm7462 antigen) on...
Skin aging represents a health and aesthetic problem that could result in infections skin diseases. Bioactive peptides can potentially be used regulation. Chickpea (Cicer arietinum L.) selenoproteins were obtained from germination with 2 mg Na2SeO3/100 g of seeds for days. Alcalase, pepsin, trypsin as hydrolyzers, membrane < 10 kDa was to fractionate the hydrolysate. Se content, antioxidant capacity, elastase collagen inhibition, functional stability, preventative capacity analyzed....
Abstract Context The tumor microenvironment (TME) includes diverse cellular components such as mesenchymal stem cells (MSCs) and immune cells, among others. MSC have been isolated from different tumors they favor cell growth; however, their role in pituitary (PTs) remains unknown. Objective Herein we report the presence of MSCs 2 adrenocorticotropin (ACTH)-secreting PTs causing Cushing disease (MCU), nonfunctioning adenomas gonadotrope differentiation (MNF), nontumoral glands (MS). Methods...
Abstract Pituitary neuroendocrine tumors (PitNET) represent the vast majority of sellar masses. Some behave aggressively, growing rapidly and invading surrounding tissues, with high rates recurrence resistance to therapy. Our aim was establish patterns genomic, transcriptomic methylomic evolution throughout time in primary recurrent from same patient. Therefore, we performed transcriptome- exome-sequencing methylome microarrays aggressive, primary, PitNET Primary showed a similar exome...
Abstract Disclosure: D. Marrero-Rodríguez: None. K. Taniguchi-Ponciano: F. Martinez-Mendoza: E. Peña-Martinez: S. Vela-Patiño: Hinojosa-Alvarez: J. Hernandez-Perez: R. Chavez-Santoscoy: Sosa-Eroza: P.E. Espinosa Cardenas: M. Mercado: Pituitary tumors (PT) represent the second most frequent intracranial tumor and this neoplasm arises from adenohypophyseal cells. Prolactin-secreting (PRL-tumors) are commonly of pituitary gland lactotrophs, account for 50% all tumors. highly heterogeneous...
Abstract Disclosure: D. Marrero-Rodríguez: None. K. Taniguchi-Ponciano: F. Martinez-Mendoza: E. Peña-Martinez: S. Vela-Patiño: Hinojosa-Alvarez: J. Hernandez-Perez: R. Chavez-Santoscoy: Sosa-Eroza: P.E. Espinosa Cardenas: M. Mercado: Pituitary tumors (PT) represent the second most frequent intracranial tumor and this neoplasm arises from adenohypophyseal cells. Prolactin-secreting (PRL-tumors) are commonly of pituitary gland lactotrophs, account for 50% all tumors. highly heterogeneous...
Chronic wounds and burns are a worldwide healthcare problem that erodes patients' well-being systems. This silent costly epidemic requires new, cost-efficient solutions to improve physical economic welfare. Eschar-degrading vegetal bacterial proteases have been utilized as solution. However, these proteins evolutionarily far from those present in human wound healing. Serine protease (SP) annexin (ANX) interact within the skin healing process. A homology-based identification pipeline can help...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Abstract Disclosure: K. Taniguchi-Ponciano: None. A. Chavez-Santoscoy: S. Hinojosa-Alvarez: J. Hernandez-Perez: Valenzuela-Perez: Vela-Patiño: Andonegui-Elguera: Cano-Zaragoza: F. Martinez-Mendoza: Kerbel: Z. Zhang: G. Smith: Rubenstein: W. Cheng: N. Mendelev: M. Amper: Zamojski: E. Zaslavsky: F.M. Ruf-Zamojski: S.C. Sealfon: Mercado: D. Marrero-Rodríguez: Pituitary tumors (PT) represent 20% of all intracranial neoplasms. Some behave aggressively, growing rapidly and invading surrounding...
Amphibian skin secretions are enriched with complex cocktails of bioactive molecules such as proteins, peptides, biogenic amines, alkaloids guanidine derivatives, steroids and other minor components spanning a wide spectrum pharmacological actions exploited for centuries in folk medicine. This study presents evidence on the protein profile canyon tree frog, Dryophytes arenicolor. At same time, it reverse-phase liquid chromatography isolation, mass spectrometry characterization identification...