A5073985755- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Characterization and Applications of Magnetic Nanoparticles
- Iron oxide chemistry and applications
- Advanced biosensing and bioanalysis techniques
- Gold and Silver Nanoparticles Synthesis and Applications
- Dendrimers and Hyperbranched Polymers
- Graphene and Nanomaterials Applications
- Immunotherapy and Immune Responses
- Nanocluster Synthesis and Applications
- Electrohydrodynamics and Fluid Dynamics
Université de Strasbourg
2021-2025
Centre National de la Recherche Scientifique
2021-2025
Institut de Physique et Chimie des Matériaux de Strasbourg
2021-2025
University of Mons
2023-2024
Functionalized iron oxide nanoparticles (IONPs) are increasingly being designed as a theranostic nanoplatform combining specific targeting, diagnosis by magnetic resonance imaging (MRI), and multimodal therapy hyperthermia. The effect of the size shape IONPs is tremendous importance to develop nanoobjects displaying efficient MRI contrast agents hyperthermia agent via combination (MH) and/or photothermia (PTT). Another key parameter that amount accumulation in cancerous cells sufficiently...
Molecular magnetic resonance imaging (MRI) holds great promise for diagnosis and therapeutic monitoring in a wide range of diseases. However, the low intrinsic sensitivity MRI to detect exogenous contrast agents lack biodegradable microprobes have prevented its clinical development. Here, we synthetized agent molecular based on previously unknown mechanism self-assembly catechol-coated magnetite nanocrystals into microsized matrix-based particles. The resulting (M3P particles) carry up...
Orientation and steric hindrance decrease the efficiency for an antibody to attach its specific receptor. Giving flexibility a dendronized peptide through small PEG fragment increases peptides affinity cellular receptors.
The controlled growth of stellate silica shells around iron oxide nanoparticles allows the design novel efficient theranostics for MRI, magnetic hyperthermia and photothermia.
Thermal decomposition is a very efficient synthesis strategy to obtain nanosized metal oxides with controlled structures and properties. For the iron oxide nanoparticle synthesis, it allows an easy tuning of nanoparticle's size, shape, composition, which often explained by LaMer theory involving clear separation between nucleation growth steps. Here, events before nanocrystals are investigated combining different complementary in situ characterization techniques. These characterizations...
Tuning the synthesis of iron oxide nanoparticles (IONPs) to modulate structural and vacancy defects has shown that IONPs with fewer are more suitable for combining MH PTT high efficiency.
Abstract The theranostic properties of gold nanoparticles (GNPs) depend on their size and shape but also challenging coating. Indeed, the GNPs coating step is not easy to perform often affects colloidal stability aggregation state. We investigated one‐pot synthesis with a higher than 10 nm coated dendrons by testing different processes. With Brust‐Schriffin method, very fast reduction HAuCl 4 growth step. decrease kinetics tuning reaction temperature NaBH injection speed led spherical ∼30...