Wan Long Pan

ORCID: 0000-0003-0745-6169
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About
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Research Areas
  • Circular RNAs in diseases
  • MicroRNA in disease regulation
  • Tissue Engineering and Regenerative Medicine
  • Neurogenesis and neuroplasticity mechanisms
  • Extracellular vesicles in disease
  • Cancer-related molecular mechanisms research
  • Traditional Chinese Medicine Studies
  • RNA modifications and cancer
  • Corneal Surgery and Treatments
  • Cardiac Imaging and Diagnostics
  • X-ray Diffraction in Crystallography
  • Fullerene Chemistry and Applications
  • Graphene and Nanomaterials Applications
  • GABA and Rice Research
  • Traditional Chinese Medicine Analysis
  • Mesenchymal stem cell research
  • Food composition and properties
  • EEG and Brain-Computer Interfaces
  • Carbon and Quantum Dots Applications
  • Medical Imaging and Analysis
  • Food Quality and Safety Studies
  • Energetic Materials and Combustion
  • Pluripotent Stem Cells Research
  • Soybean genetics and cultivation
  • Chemical Reactions and Mechanisms

Lanzhou University
2024-2025

Institute of Crop Sciences
2025

Traditional Chinese Medicine Hospital of Kunshan
2024

Shanghai University of Traditional Chinese Medicine
2024

Rice Research Institute
2024

Sichuan Agricultural University
2024

Wuhan University
2024

Affiliated Hospital of North Sichuan Medical College
2019

Henry Ford Hospital
2019

Henry Ford Health System
2016

Impairment of adult neurogenesis in the hippocampus causes cognitive deficits; however, underlying molecular mechanisms have not been fully elucidated. microRNAs (miRNAs) regulate neural stem cell (NSC) function. With use a transgenic mouse line with conditional ablation miR-17-92 cluster nestin lineage NSCs, we tested hypothesis that regulates and function vivo. Compared wild-type mice, significantly reduced number proliferating NSCs neuroblasts neuronal differentiation dentate gyrus (DG)...

10.1096/fj.201801019r article EN The FASEB Journal 2019-01-22

The fairness of long-term self-renewal and robust cell proliferation limits the applications human mesenchymal stem cells (hMSCs) in regenerative medicine. Inducing hMSCs from human-induced pluripotent (hiPSCs), which have advantages autogenous no number issues, is highly valuable. However, current induction methods using FBS-containing culture medium problems, including immunogenicity, microbial contamination, low efficiency. To solve these we propose a chemically defined protocol...

10.1021/acsami.4c13686 article EN ACS Applied Materials & Interfaces 2025-02-20

<title>Abstract</title> Circadian rhythm is an evolutional strategy to govern cellular processes adapt periodic environmental conditions. The mechanism of circadian clock regulation metabolism well known and widely applied in animals human, but poor plants. Here, elucidate environmental, genetic metabolic circadian-integration plants, we comprehensively investigated phase- tissue-specific transcript metabolite clusters soybean pods found that pod walls seeds are gifted with diverse rhythms...

10.21203/rs.3.rs-5535877/v1 preprint EN cc-by Research Square (Research Square) 2025-03-05

The widespread occurrence of microplastics (MPs) in the environment has raised significant concerns regarding their potential health impacts, particularly relation to carcinogenesis. This study aimed identify and analyze present peritumoral tumor tissues patients diagnosed with colorectal cancer (CRC). Utilizing advanced scanning electron microscopy (SEM) laser direct infrared (LDIR) imaging systems, we systematically examined tissue samples detect characterize microplastics. Our findings...

10.1038/s41598-025-98268-6 article EN cc-by-nc-nd Scientific Reports 2025-05-08

Neurogenesis is associated with functional recovery after stroke. However, the underlying molecular mechanisms have not been fully investigated. Using an Ago2-based RNA immunoprecipitation to immunoprecipated Ago2-RNA complexes followed by sequencing (Ago2 RIP-seq) approach, we profiled miRNomes in neural progenitor cells (NPCs) harvested from subventricular zone (SVZ) of lateral ventricles young adult rats. We identified more than 7 and 15 million reads normal ischemic NPC libraries,...

10.1080/15476286.2016.1196320 article EN RNA Biology 2016-06-17

Taste quality is one of the most important indicators for assessing rice. However, there has been a lack systematic studies investigating impact factors taste quality. In this study, chromosomal segment substitution lines (CSSLs) with notable differences in physicochemical properties were obtained by screening CSSL population. A correlation analysis between and qualities rice revealed that amylose protein content are significantly negatively correlated value both freshly cooked rehydrated...

10.3389/fpls.2024.1481207 article EN cc-by Frontiers in Plant Science 2024-11-07

Background: Stable angina pectoris, resulting from coronary artery atherosclerosis, significantly affects quality of life and carries a high risk cardiovascular events. Despite modern therapies, managing this condition remains challenging. Traditional Chinese medicine (TCM) views it as syndrome heart meridian obstruction by phlegm blood stasis, necessitating improved circulation resolution. This study aims to evaluate the efficacy Jiangzhi Mai’an Granules, TCM formulation, in treating stable...

10.1097/md.0000000000040787 article EN cc-by-nc Medicine 2024-12-06

10.1109/robio64047.2024.10907364 article EN 2021 IEEE International Conference on Robotics and Biomimetics (ROBIO) 2024-12-10
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