A5007778281- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Patient-Provider Communication in Healthcare
- Education, Healthcare and Sociology Research
- Interprofessional Education and Collaboration
- Patient Dignity and Privacy
- Family Support in Illness
- Health, psychology, and well-being
- Diabetes Management and Education
- Mental Health and Patient Involvement
- Patient Satisfaction in Healthcare
- Spinal Fractures and Fixation Techniques
- Pain Management and Opioid Use
- Health Policy Implementation Science
- Geriatric Care and Nursing Homes
- Social and Educational Sciences
- Health Systems, Economic Evaluations, Quality of Life
- Management of metastatic bone disease
- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Posttraumatic Stress Disorder Research
- Sexual function and dysfunction studies
- Hemoglobin structure and function
- Global Cancer Incidence and Screening
Zealand University Hospital
2022-2025
University of Southern Denmark
2016-2023
Bispebjerg Hospital
2013-2022
Copenhagen University Hospital
2014-2021
Frederiksberg Hospital
1982-2021
University of Birmingham
2021
University of Copenhagen
1986-2020
Contextual Change (United States)
2020
Kalmyk Institute for Humanities Research
2005-2018
Hvidovre Hospital
1989-2015
Knowledge of health related quality life haematological patients is limited. This study aimed at investigating the prevalence and predictors symptoms problems in a representative sample Denmark.A random with leukaemia, multiple myeloma advanced lymphoma (n = 732) received European Organisation for Research Treatment Cancer quality-of-life questionnaire (EORTC QLQ-C30). Mean scores were calculated. In addition, dichotomised using two thresholds: reporting least 'a little' each EORTC QLQ-C30...
Background Advance care planning (ACP) supports individuals to define, discuss, and record goals preferences for future medical treatment care. Despite being internationally recommended, randomised clinical trials of ACP in patients with advanced cancer are scarce. Methods findings To test the implementation cancer, we conducted a cluster-randomised trial 23 hospitals across Belgium, Denmark, Italy, Netherlands, Slovenia, United Kingdom 2015–2018. Patients lung (stage III/IV) or colorectal...
Little is known about the need for palliative care among advanced cancer patients who are not in specialist care. The purpose was to identify prevalence and predictors of symptoms problems a nationally representative sample Danish patients. Patients with stage 3 or 4 from 54 hospital departments ( n = 1630) received EORTC QLQ-C30 questionnaire. Mean scores were calculated according scoring manual addition ‘symptom/problem’ ‘severe symptom/problem’ defined calculated. Multiple logistic...
Background: Beneficial effects of early palliative care have been found in advanced cancer, but the evidence is not unequivocal. Aim: To investigate effect specialist among cancer patients identified oncology departments. Setting/participants: The Danish Palliative Care Trial (DanPaCT) (ClinicalTrials.gov NCT01348048) a multicentre randomised clinical trial comparing referral to team plus standard versus alone. planned sample size was 300. At five departments, consecutive with were screened...
Regional cerebral blood flow (rCBF) was measured with high resolution brain dedicated single photon emission computer tomography (SPECT) and [99mTc]-d,l-hexamethyl-propylene-amine-oxime (HMPAO) in 25 patients probable Alzheimer9s disease control subjects, selected according to rigorous inclusion exclusion criteria. The aim analyse the topography of rCBF deficits individual patients. In group as a whole, global CBF reduced, but factorial analysis variance did not show disproportionate...
Awareness of preferences regarding medical care should be a central component the patients with advanced cancer. Open communication can facilitate this but occur in an ad hoc or variable manner. Advance planning (ACP) is formalized process between patients, relatives and professional caregivers about patients' values preferences. It raises awareness need to anticipate possible future deterioration health. ACP has potential improve current healthcare decision-making, provide sense control,...
Abstract Background Burnout is a critical factor that can influence the quality of care doctors provide to their patients. Previous research suggests link between inadequate communication skills training and burnout, various approaches enhance have been explored as means address this issue. However, evidence effect these lacking. The aim study assess novel On-site Supportive Communication Training (On-site SCT) in enhancing among oncologists thereby addressing burnout. Methods This...
To explore the experiences of patients with advanced cancer regarding timing ACP. This secondary analysis used data from ACTION cluster-randomized clinical trial. 288 lung or colorectal cancer, WHO performance status 0-3, and a minimum life expectancy 3 months were included in this analysis. The mean time between patients' diagnosis first ACP conversation was 15.3 (SD:19.4). average duration current stage to 8.9 (SD:10.7). perceived as "just right" by 217 (75.3 %) patients. Patients who "too...
Abstract Objectives The aim of the study was to investigate adequacy help delivered by healthcare system for 12 symptoms/problems in a national, randomly selected sample advanced cancer patients Denmark. Methods Advanced ( n = 1630) from 54 hospital departments across Denmark received 3‐Levels‐of‐Needs Questionnaire (3LNQ). 3LNQ measures ‘problem burden’, degree which symptom or problem is perceived as problem, and ‘felt need’, whether patient receives adequate help. Prevalences were...
BACKGROUND Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect melatonin on in patients cancer. METHODS who were aged ≥18 years, had a histologically confirmed stage IV (TNM Classification), reported feeling significantly tired recruited from palliative care unit at study institution. was double‐blind, randomized, placebo‐controlled crossover trial. received 1 week dose 20 mg or...
Background: Sexual dysfunction and problems are common late effects after treatment of cancer. However, little is known about the prevalence risk factors for sexual in patients with advanced The aim this study was to investigate predictors needs a large sample Danish cancer.Methodology: data derived from representative cross-sectional Patients who had been contact 1 54 hospital departments were invited fill out questionnaire on symptoms problems. Five items asked sexuality. Ordinal logistic...
1. Studies of the influence clinically relevant concentrations vigabatrin on GABA‐transaminase and release endogenous GABA were performed in selectively cultured astrocytes neurons. In addition, two stereoisomers investigated separately. 2. The results indicated a preferential inhibition neuronal by vigabatrin. 3. Only (S)‐form seems to inhibit GABA‐transaminase. This finding corresponds observations epileptic animals that (R)‐form exhibits no anticonvulsant effect. 4. Resynthesis...
Background: Patient empowerment (PE) may be defined as the opportunity for patients to master issues important their own health. The aim of this study was conceptualize PE and how concept manifests itself cancer attending follow-up, in order develop a relevant sensitive questionnaire population.Material methods: A theoretical model made, based on Zimmerman's theory psychological empowerment. Patients who were follow-up after first line treatment (n = 16) interviewed about experiences with...
Background: People with advanced cancer face difficulties their everyday activities at home that may reduce health-related quality of life. To address these difficulties, we developed the ‘Cancer Home-Life Intervention’. Aim: evaluate efficacy Home Life-Intervention’ compared usual care regard to patients’ performance of, and participation in, activities, Design intervention: A randomised controlled trial ( ClinicalTrials.gov NCT02356627). The Intervention’ is a brief, tailored, occupational...
During the past decade an increasing number of people live with advanced cancer mainly due to improved medical treatment. Research has shown that many have problems everyday activities, which negative impact on their quality life, and they spend a considerable part time at home. Still, research interventions support performance participation in activities is only scarcely available. Therefore, occupational therapy-based "Cancer Home-Life Intervention" consisting tailored adaptive applied...
Background: Palliative home-care teams often cooperate with general practitioners (GPs) and district nurses. Our aim was to evaluate a palliative team from the viewpoint of GPs Methods: nurses received questionnaires at start one month later. Questions focussed on benefits patients, training issues for professionals cooperation between GP/ nurse. A combination closed-and open-ended questions used. Results: Response rate 84% (467/553). Benefits patients were experienced by 91%, mainly due...
Background. Cancer care usually involves several health professionals from different parts of the system. Often, GP has an important role. Patients' experiences continuity and support may be related to characteristics care, disease or patients. Objectives. To investigate Danish cancer patients' their contact cooperation between hospital. Methods. A national cross-sectional questionnaire study in three representative counties Denmark. Based on a review medical records all hospital departments...