A5076679100- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Multiple Myeloma Research and Treatments
- Hemoglobinopathies and Related Disorders
- Platelet Disorders and Treatments
- Complement system in diseases
- Viral-associated cancers and disorders
- Acute Myeloid Leukemia Research
- Blood donation and transfusion practices
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Blood groups and transfusion
- Acute Lymphoblastic Leukemia research
- Hematopoietic Stem Cell Transplantation
- Eosinophilic Disorders and Syndromes
- Iron Metabolism and Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
- CNS Lymphoma Diagnosis and Treatment
- Blood transfusion and management
- Protein Degradation and Inhibitors
- Endometriosis Research and Treatment
- Adenosine and Purinergic Signaling
- Cutaneous lymphoproliferative disorders research
Pamukkale University
2015-2024
Bursa Uludağ Üni̇versi̇tesi̇
2013
The efficacy of methotrexate (MTX), a widely used cytotoxic chemotherapeutic agent, is often limited by its severe hepatotoxicity. Regarding the mechanisms these adverse effects, several hypotheses have been put forward, among which oxidative stress noticeable. present study was undertaken to determine whether grape seed extract (GSE), new natural free radical scavenger, could ameliorate MTX-induced injury in rat liver. animals were divided into 3 groups. Each group consisted 12 animals....
Abstract The aim of the study is to review clinical manifestations and hematological findings brucellosis pancytopenia, with or without malignancies. records 202 patients were evaluated retrospectively. Among these cases seen in a 6 year period between April 1999 June 2005, 30 pancytopenia identified. most common manifestation was fever, followed by weight loss, anorexia, malaise, arthralgia, hepatosplenomegaly. Bone marrow biopsies revealed hypercellularity normocellularity. bone evaluation...
Screening for thyroid autoimmunity in patients with chronic idiopathic urticaria (CIU) is generally recommended. However, there are not yet sufficient data as to whether levothyroxine treatment beneficial the clinical symptoms of CIU autoimmunity.We investigated effect on and serum tumour necrosis factor (TNF)-alpha, interleukin (IL)-10 interferon (IFN)-gamma levels euthyroid autoimmunity.In total, 15 positive autoantibodies were randomized receive either plus 5 mg/day desloratadine...
Abstract In this multicenter retrospective analysis, we aimed to present clinical, laboratory and treatment results of 94 patients with Hairy cell leukemia diagnosed in 13 centers between 1990 2014. Sixty‐six the were males 28 females, a median age 55. Splenomegaly was 93.5% cases at diagnosis. The findings that came into prominence pancytopenia grade 3 bone marrow fibrosis. Most an indication for treated cladribine as first‐line treatment. Total complete response 97.3% 80.7%. relapse rate...
The aim of the study was to evaluate effect Controlling Nutritional Status (CONUT) score on prognosis in patients with diffuse large B-cell lymphoma (DLBCL).The present a retrospective study. CONUT calculated based serum albumin, total cholesterol and lymphocyte levels. This included 266 patients, 131 (49.2%) were female 135 (50.8%) male. median follow-up period 51 months (range: 1–190).The age 64 years. cut off 1.5. There significant difference between high (≥ 2) or low (< scores terms...
Infectious complications in febrile neutropenic patients are still major causes of morbidity and mortality despite significant advances diagnostic techniques antimicrobial therapy. In this study, we describe the characteristics with hematological malignancies who were evaluated for suspected infection. This study was also conducted to assess isolation rate bacterial fungal causative agents attacks.The at Pamukkale University Hospital, Turkey. order identify presence/suspicion any...
Background: A variety of apheresis devices are now available on the market for plateletapheresis. We compared two instruments (Fenwal Amicus and Fresenius COM.TEC) with regard to processing time, platelet (PLT) yield efficiency, white blood cell (WBC) content. Material Methods: Donors undergoing plateletpheresis were randomly separated into groups (either or COM.TEC separator). Results: In pre-apheresis setting, 32 procedures performed each instrument revealed no significant differences in...
Spectrophotometric intracutaneous analysis (SIAscopy) is a recently introduced, noninvasive, rapid and practical method for monitoring pigmented lesions, which calculates the amount of collagen, melanin haemoglobin deep in papillary dermis.To evaluate value SIAscopy diagnosis nonmelanoma skin cancers (NMSC).In total, 80 lesions 76 patients were clinically evaluated by first investigator, data recorded. Eight months after clinical evaluation, all again same using images (SIAgraphs) obtained...
Background: Myeloid differentiation primary response 88 (MYD88) is a common adaptor protein that responsible for signaling from several receptors; mutations in this gene may play role the pathogenesis of lymphoma. Aim: We aimed to determine MYD88 L265P mutation frequency, level expression, and their associations with clinicopathological parameters mature B-cell non-Hodgkin lymphomas (NHLs). Methods: A total 68 patients were included study. The presence was analyzed by real-time polymerase...
In this study, the authors aimed to evaluate frequency of pulmonary hypertension (PHT) in asymptomatic thalassemia major (TM) patients, and investigate impact function test (PFT) CO diffusion results on evaluation hypertension. Data from 50 patients with TM over age 10 were evaluated. Pulmonary was diagnosed (20%). High tricuspid regurgitant jet velocity found 14% adults 25% children. including testing not different between or without conclusion, PHT frequent among even they although PFT has...
Chronic lymphocytic leukaemia often has a clinical presentation characterised by increased neoplastic lymphocytes which are mostly mature looking due to B lymphocytes. Increased secondary cancer prevalence been detected among patients with chronic diagnosis. In this report, we present three who developed rare cancers during their follow-up at our clinic. Case 1: A 54-year-old female patient was diagnosed stage I in 2003 and Merkel cell carcinoma February 2013. 2: 66-year-old male II 2009...
The aim of this study was to determine the frequency haemostatic abnormalities in women with menorrhagia and evaluate their effect on quality life (QoL). population composed patients seen outpatient clinic, having a score >185 pictorial blood assessment chart. Structured questionnaires were used demographic characteristics QoL, tested for bleeding disorders. Ninety recruited study. Bleeding disorders detected 40% them: 11.1% had von Willebrand disease, 2.2% low factor 26.7% platelet function...