A5102923653- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Analytical Chemistry and Chromatography
- Electrochemical sensors and biosensors
- Electrochemical Analysis and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Analytical Chemistry and Sensors
- Analytical Methods in Pharmaceuticals
- Nanopore and Nanochannel Transport Studies
- Analytical chemistry methods development
- Advanced Chemical Sensor Technologies
- Bacteriophages and microbial interactions
- Extracellular vesicles in disease
- Molecular Sensors and Ion Detection
- Circular RNAs in diseases
- Gas Sensing Nanomaterials and Sensors
- Chromatography in Natural Products
- MicroRNA in disease regulation
- Plant and Fungal Species Descriptions
- Environmental and Agricultural Sciences
- Opportunistic and Delay-Tolerant Networks
- Light effects on plants
- Pharmacological Effects and Assays
- Phytochemistry and Biological Activities
- Spectroscopy and Chemometric Analyses
East China Normal University
2016-2025
Hebei University of Engineering
2006-2019
Wuhan University
2016
Tianjin Research Institute of Electric Science (China)
2016
First Affiliated Hospital of Xinxiang Medical University
2015
A Faraday-cage-type electrochemical aptasensor based on two-dimensional (2D) nanomaterials was developed for the sensitive detection of Escherichia coli O157:H7. In this aptasensor, 2D titanium carbide (Ti3C2Tx) MXene used electrode modification. Ti3C2Tx could immobilize aptamers via chelation between and phosphate groups provide a large electroactive surface signal transduction. Another zirconium ferrocene-based metal–organic framework (Zr-Fc MOF) combined with gold nanoparticles (AuNPs)...
Monoclonal antibodies (mAbs) are widely used in tumor and autoimmune disease therapy clinical diagnosis, but they suffer from self-aggregation, particularly dimer formation, impacting their stability, efficacy, potentially causing severe allergies. Traditional methods for detecting mAb dimers, such as TEM, AUC, DLS, SEC, CE, limited by low throughput, high costs, qualitative data, making them unsuitable large-scale sample assays biopharmaceuticals industry well antibody research. To address...
Abstract We report a method for the detection of DNA hybridization in connection to lead sulfide (PbS) nanoparticle tags and electrochemical stripping measurement lead. A kind with free carboxyl groups on its surface was synthesized aqueous solution. The used as marker label sequence‐known oligonucleotide, which then employed probe identifying target ssDNA immobilized PPy modified electrode based specific reaction. events were monitored by oxidation dissolution anchored hybrids indirect...
Current strand displacement amplification (SDA)-based nucleic acid sensing methods generally rely on a ssDNA template that involves complementary bases to the endonuclease recognition sequence, which has limitation of detecting only short acids. Herein, new SDA method in defective T junction structure is first used support (dT-SDA) was proposed and applied longer DNA detection. In dT-SDA, an auxiliary probe primer were designed specifically identify target gene, following formation stable...
Efficient, accurate, and economical detection of pathogenic bacteria is crucial in ensuring food safety preventing foodborne illnesses. How to fulfill the highly sensitive simultaneous multiple trace a big challenge. In this work, capillary electrophoresis coupled with cyclic primer generation rolling circle amplification (cyclic MPG-RCA) was studied for three kinds bacteria. The MPG-RCA based on carefully designed clover-shaped DNA probe, which "leaves" corresponded types aimed bacteria:...
Domestic monitoring devices make real-time and long-term health possible, allowing people to track their status regularly. Uric acid (UA), creatinine, urea in urine are three important biomarkers for various diseases, especially kidney diseases. This work proposed a 10-channel potentiometric sensing array containing UA electrode group, creatinine pH one pair of reference channels, which could be connected with portable analyzer, realizing the simultaneous detection UA, urea, urine. The...
Home potentiometric sensing devices can real-time monitor personal health status and are widely used in the prevention management of related diseases. However, variations composition pH sample matrix tend to change basic potential response slope some sensors, thus affecting detection reliability. Therefore, this work uses urea urine as a model improve reliability sensor home detection. Au@urease nanoparticles were synthesized material stability urease-based sensor. Meanwhile, multicalibrated...