Rakesh Ghimire

ORCID: 0000-0003-0775-262X
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About
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Research Areas
  • Pesticide Exposure and Toxicity
  • Poisoning and overdose treatments
  • Pharmaceutical Practices and Patient Outcomes
  • Antibiotic Resistance in Bacteria
  • Multiple Sclerosis Research Studies
  • Pharmacovigilance and Adverse Drug Reactions
  • Antibiotic Use and Resistance
  • COVID-19 Pandemic Impacts
  • HIV/AIDS drug development and treatment
  • Gas Sensing Nanomaterials and Sensors
  • Pharmacological Effects and Toxicity Studies
  • Pharmaceutical industry and healthcare
  • Pharmaceutical Quality and Counterfeiting
  • Pharmaceutical Economics and Policy
  • Insect and Pesticide Research
  • Fungal Infections and Studies
  • Entrepreneurship Studies and Influences
  • Diabetes Management and Education
  • Vaccine Coverage and Hesitancy
  • High Altitude and Hypoxia
  • Bacterial Identification and Susceptibility Testing
  • Travel-related health issues
  • Environmental Toxicology and Ecotoxicology
  • Streptococcal Infections and Treatments
  • Neonatal and Maternal Infections

Tribhuvan University Teaching Hospital
2019-2025

Tribhuvan University
2020-2024

Biratnagar Eye Hospital
2021

Rochester General Hospital
2020

Introduction Intentional pesticide poisoning is a major clinical and public health problem in agricultural communities low middle income countries like Nepal. Bans of highly hazardous pesticides (HHP) reduce the number suicides. We aimed to identify these by reviewing data from hospitals across country forensic toxicology laboratories.Methods retrospectively reviewed medical records 10 for poisoned patients two laboratories Nepal April 2017 February 2020. The poison was identified history,...

10.1080/15563650.2021.1935993 article EN cc-by-nc-nd Clinical Toxicology 2021-06-14

Abstract Background: Hypertension is a leading risk factor to Nepal's rising burden of cardiovascular diseases, yet many affected individuals remain undiagnosed, untreated, and uncontrolled. Identifying gaps in care variations across socio-demographics provinces can help optimize interventions prevent control hypertension. Objectives: We aimed quantify the prevalence hypertension awareness, treatment, control, as well their determinants, using latest nationally representative data from 2022...

10.1101/2025.03.10.25323662 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-03-11

Tribhuvan University Teaching Tertiary Care Hospital, Kathmandu, Nepal, May-October 2019.1) To describe the bacteriological profile, 2) to identify antimicrobial resistance (AMR) pattern, and 3) find demographic characteristics associated with presence of bacterial growth multidrug (MDR) in adult urine samples undergoing culture drug susceptibility testing.This was a hospital-based, cross-sectional study using routine laboratory records.Among 11,776 samples, 16% (1,865/11,776) were...

10.5588/pha.21.0035 article FR cc-by Public Health Action 2021-11-01

Abstract Background Nepal recorded 5754 suicides in 2018–19 - a high number for relatively small country. Over 24% of these were by poisoning, most ingestion highly concentrated agricultural pesticides. has actively regulated pesticides to reduce their health impacts since 2001. We aimed analyse Nepal’s history pesticide regulation, responsible poisonings, and relate them national suicide rates. Methods Information on regulation was collected from the Plant Quarantine Pesticide Management...

10.1186/s12889-021-11155-3 article EN cc-by BMC Public Health 2021-06-14

Background: Drug Promotional Literatures are usually relied upon for drug promotion, however studies have shown them to contain several pitfalls. World Health Organization has time and often revised the guideline address issue Ethical Criteria Medicinal Promotion was established. Based on this guideline, regional as well national guidelines been formulated. Though laws regulate promotion is existent, problems with promotional literatures in Nepal also. This study carried out analyse...

10.33314/jnhrc.v17i3.1840 article EN Journal of Nepal Health Research Council 2019-11-13

Abstract In recent times, the importance of nanostructure metal oxide semiconductor (MOS) as a gas sensing material is rising tremendously. Among various semiconductors ZnO has potential to be used sensor for several toxic gases. this work, we investigated influence Fe doping into detect concentrations ethanol vapour. Pristine and doped (Fe-ZnO) films were deposited on glass substrates using spin coating technique wherein concentration can easily controlled. The crystallite size surface...

10.1088/1742-6596/1706/1/012036 article EN Journal of Physics Conference Series 2020-12-01

Toxicological emergencies present a significant health challenge in Nepal. Despite the high burden, country has inadequate formal toxicology training, medical expertise, and adequate poison control infrastructure. In recognition of this need, Nepal Poison Information Center (PIC) was established as collaborative effort involving local international partners. Through comprehensive partnership framework, PIC provides 24 hours day, 7 days week expert guidance to care workers, conducts...

10.9745/ghsp-d-24-00142 article EN cc-by Global Health Science and Practice 2024-08-30

Introduction: Drug interactions are one of the major contributors to increase hospital stay, inflate health care expenses, and cause serious adverse events end-organ damage. Patients admitted intensive unit already critically sick at greater risk these outcomes. The study aimed find out prevalence potential drug-drug in Intensive Care Units a tertiary centre. Methods: A descriptive cross-sectional was conducted among patients Unit from April-June 2019. Ethical approval taken Institutional...

10.31729/jnma.7137 article EN Journal of Nepal Medical Association 2022-03-11


 Introduction: Globally, Adverse Drug Reaction (ADR) has been listed as the sixth leading causes of death. Recognition ADR and establishment relationship drug with symptom is first step to management problem. In this study, Naranjo algorithm used which one most accepted tools for assessment causality suspected drug.
 Methods: A retrospective descriptive study was done included 35 reported cases ADRs in Information Unit (DIU) tertiary care teaching institute Nepal from Dec 2015 Oct...

10.3126/mjsbh.v19i1.21573 article EN cc-by-nc-nd Medical Journal of Shree Birendra Hospital 2020-01-14

Paraquat, a highly toxic herbicide, accounts for substantial number of poisoning-related fatalities, primarily prevalent in agricultural regions. The ingestion gives rise to severe complications affecting various organs, including the lungs, gastrointestinal tract, kidneys and liver. This report details case an 18-year-old male who had been using cannabis year inadvertently ingested paraquat. He presented at emergency room exhibiting symptoms vomiting characterized by hematemesis...

10.1177/2050313x241240098 article EN cc-by-nc SAGE Open Medical Case Reports 2024-01-01

<h3>Background</h3> Suicide is one of the most common types injuries in Nepal with recorded 6993 suicides 2022–23, intentional pesticide poisoning being second method. Banning highly hazardous pesticides (HHPs) a cost-effective intervention to reduce mortality from suicide. Eight mostly HHPs were banned 2019 product reformulated. <h3>Objective</h3> This talk will provide highlights University Edinburgh study on use suicides. HOPE GRID (2017–2019) carried out select hospitals and toxicology...

10.1136/injuryprev-2024-safety.356 article EN 2024-08-30

Purpose: The purpose of the paper is to identify moderating role socially constructed gender-based norms in relationship between institutional support and entrepreneurial survivability based on women entrepreneurs' perceptions. Method/ Design: study follows a causal research design. population comprises all entrepreneurs from over Nepal with purposively selected 353 samples conveniently four provinces. moderation effect was tested application Structural Equation Modeling institution theory...

10.3126/irjms.v9i1.72721 article EN International Research Journal of Management Science 2024-12-29

SETTING: Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. OBJECTIVE: To determine the pattern of antimicrobial resistance hospital exit outcomes in neonates with suspected sepsis a tertiary neonatal intensive care unit (NICU). DESIGN: This hospital-based cohort study was conducted to follow patients from January December 2019. All identified cases were enlisted records. RESULTS: Sepsis 177 (88%) 200 admitted NICU; 52 (29%) culture-positive. Pseudomonas predominant organism...

10.5588/pha.21.0038 article EN cc-by Public Health Action 2021-11-01

The world has faced huge negative effects from the COVID-19 pandemic between early 2020 and late 2021. Each country implemented a range of preventive measures to minimize risk during pandemic. This study assessed COVID-19-related fear, perception, preventative behavior nationwide lockdown due in Nepal. In cross-sectional study, conducted mid-2021 Nepal, total 1484 individuals completed on fear COVID-19, behavior. A multiple linear regression analysis was used identify factors associated with...

10.3390/vaccines11010029 article EN cc-by Vaccines 2022-12-23
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