A5031267160- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 epidemiological studies
- Global Public Health Policies and Epidemiology
- COVID-19 Pandemic Impacts
- Pharmaceutical Quality and Counterfeiting
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Ethics in Clinical Research
- Respiratory Support and Mechanisms
- Antibiotic Use and Resistance
- Global Cancer Incidence and Screening
- Pharmaceutical Economics and Policy
- COVID-19 and healthcare impacts
- Emergency and Acute Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Family and Patient Care in Intensive Care Units
- Vaccine Coverage and Hesitancy
- Sepsis Diagnosis and Treatment
- Diverse Scientific Research Studies
- Smoking Behavior and Cessation
- SARS-CoV-2 detection and testing
- Immune responses and vaccinations
- COVID-19 diagnosis using AI
- COVID-19 Impact on Reproduction
Nepal Health Research Council
2016-2024
Ministry of Health and Population
2021-2024
Tribhuvan University
2020-2023
Tribhuvan University Teaching Hospital
2020-2022
NIHR Clinical Research Network
2021
National Institute for Health Research
2021
National Records of Scotland
2021
Public Health Scotland
2021
University Hospitals Birmingham NHS Foundation Trust
2021
Public Health England
2021
Background The World Health Organization (WHO) recommends ongoing surveillance of non-communicable diseases (NCDs) and their risk factors, using the WHO STEPwise approach to (STEPS). aim this study was assess distribution determinants NCD factors in Nepal, a low-income country, which two-thirds (66%) annual deaths are attributable NCDs. Methods A nationally representative STEPS survey (instrument version 3.2), conducted between February May 2019, among 6,475 eligible participants age 15–69...
BackgroundPaediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 (PIMS-TS), also known as in children (MIS-C) emerged April, 2020. The paediatric comparisons within the RECOVERY trial aimed to assess effect of intravenous immunoglobulin or corticosteroids compared usual care on duration hospital stay for PIMS-TS and compare tocilizumab (anti-IL-6 receptor monoclonal antibody) anakinra (anti-IL-1 antagonist) those inflammation refractory initial treatment.MethodsWe...
Mental disorders account for a large portion of burden disease. In Nepal, the prevalence mental has been rising steadily, but national and province level is not available. This study aims to assess common suicidality in Nepal.We conducted nationwide descriptive cross-sectional community-based among adults (aged 18 years above) adolescents 13 17 years) Nepal. We included total 9200 5888 from seven provinces Nepal by using multistage Probability Proportionate Size sampling technique. were...
The burden of diabetes mellitus (DM) has increased globally, particularly in low-income and middle-income countries, including Nepal. Population-based nationally representative data on the prevalence DM is limited. This paper presents its associated risk factors Nepal.This population-based study sampled 13 200 participants aged 20 years above 400 clusters 72 districts used a standardised questionnaire adapted from WHO STEPwise approach to non-communicable disease factor surveillance...
<ns3:p>Background This study aimed to assess the current status of critical care services in 13 districts Bagmati Province Nepal, with a focus on access, infrastructure, human resources, and intensive unit (ICU) services. Methods A cross-sectional survey was conducted among healthcare workers employed 87 hospitals having medical/surgical ICUs across Province. Data were collected through structured questionnaires administered via face-to-face telephone survey. Descriptive analysis used for...
This study aimed to determine population-based prevalence of chronic kidney disease (CKD) and its associated factors in Nepal.The was a nationwide cross-sectional study.Cross-sectional survey conducted nationally representative sample 12 109 Nepalese adult from 2016 2018 on selected non-communicable diseases examined. Multistage cluster sampling with mix probability proportionate size systematic random used for the selection individuals aged 20 years above.Primary outcome this CKD Nepal. A...
Although cancer is an important and growing public health issue in Nepal, the country lacked any population-based registry (PBCR) until 2018. In this study, we describe establishment of PBCR for first time Nepal use data to understand incidence, mortality, patterns Kathmandu Valley (consisting Kathmandu, Lalitpur, Bhaktapur districts), which comprises 10.5% estimated 29 million population 2018.The collects information from facilities communities through active process. The include or general...
Essential medicines are those that satisfy the primary health care needs of citizens. Poor quality essential can have serious impact on public health. Thus, this study is aimed to assess available in facilities Nepal. A cross sectional descriptive was carried out 62 across 21 districts, representing all seven provinces Nepal and selected proportionately from three ecological regions i.e. Terai, Hill Mountain using lottery method. Health districts were chosen random number generator. Face...
Background . Cancer is one of the leading causes death globally. The low and middle‐income countries (LMICs) cover a major share global cancer burden; however, most LMICs including Nepal still lack national control prevention strategies. Since 1 st January 2018, Health Research Council (NHRC) started population‐based registry (PBCR) in urban, suburban, rural regions to support evidence‐based intervention each geographical region. Methods Data regarding incidence mortality was collected by...
Abstract Background Convalescent plasma therapy (CPT) and remdesivir (REM) have been approved for investigational use to treat coronavirus disease 2019 (COVID-19) in Nepal. Methods In this prospective, multicentered study, we evaluated the safety outcomes of treatment with CPT and/or REM 1315 hospitalized COVID-19 patients over 18 years 31 hospitals across was administered moderate, severe, or life-threatening infection. severe infections who were at high risk progression clinical worsening...
<ns4:p>Background This study aimed to assess the current status of critical care services in 13 districts Bagmati Province Nepal, with a focus on access, infrastructure, human resources, and intensive unit (ICU) services. Methods A cross-sectional survey was conducted among healthcare workers employed 87 mixed medical/surgical ICUs across Province. Data were collected through structured questionnaires administered via face-to-face telephone interviews. Descriptive analysis used for data...
Nepal is one of the high prevalent countries for tobacco use in Southeast Asia regions. Tobacco related cancer share major burden since a decade, however, population-based estimates still lacking. This study provides results from registries on tobacco-related (TRCs) Nepal.
Introduction: The practice of medicine is an honorable profession besides being accompanied by a demanding environment. This study aimed to find out the professional quality life medical doctors working in Kathmandu valley.
 Methods: A descriptive cross-sectional was conducted among 174 Nepalese different hospitals valley. Ethical approval taken from Review Board Nepal Health Research Council (Reference Number: 830). data collection tool used WHO Professional Quality Life Scale-5...
Background: Preparedness, readiness, and response status of any country is integral in identifying, managing, preventing COVID-19 pandemic. The objective this study to assess the Government Nepal designated COVID hospitals clinics respond against COVID-19. Methods: A cross sectional was conducted with focal persons using a semi-structured questionnaire from April 26, 2020 May 27, via face interview onsite observation telephonic few unreachable health facilities. Results: demonstrated efforts...
Variations in cancer incidence, mortality and pattern exist rural urban areas.Understanding these differences helps developing targeted prevention control strategies.However, no previous studies have explored the demographics between areas of Nepal.The data Kathmandu Valley (urban area) Population-Based Cancer Registry (PBCR) Rukum (rural PBCR were analysed to identify areas.The age-adjusted incidence rate (AAR) was higher than that (1.6 times among males 1.9 females).The top two leading...
NA
Background: The Global Burden of Diseases Study 2017 predicted that chronic obstructive pulmonary disease (COPD) is the second leading cause death, fourth premature and third for DALYs lost in Nepal. However, data on population-based prevalence COPD Nepal are very limited. This study aims to assess factors associated with occurrence Methods: From a nationally representative, cross-sectional non-communicable diseases, its was determined. Of 12,557 participants aged over 20 years, 8945...
Background Nepal adopted the Multisectoral Action Plan for Prevention and Control of Non-Communicable Diseases (MSAP) in 2014. Implementation plan has been challenging, with limited participation from non-health sectors.Objectives The overall aim study was to gain perspectives key stakeholders involved MSAP on barriers facilitators its implementation, through relevant sectors plan.Methods We held face-to-face semi-structured interviews 12 working MSAP. These included Office Prime Minister...
Type 2 diabetes mellitus (T2DM) is a common chronic condition with significant health and socioeconomic consequences. In Nepal, T2DM disease for which people consult ayurvedic (traditional medical system) practitioners use medicines. Strong concerns remain about the suboptimal management of many patients by practitioners, therefore, based on best available scientific evidence, we have developed clinical guideline managing practitioners. The research question to be addressed definitive...
Having an anti-diabetic activity, Aloe Vera (Aloebarbadensis) has been used for medicinal purposes in several cultures millennia. It also proved that aloe vera is having protective activity nephrotoxic rats.The objective of the present study was to evaluate effect leaves extract on diabetic nephropathy Streptozotocin-induced rat. Diabetes induced by Streptozotocin(60 mg/kg-i.p.). Four weeks later rats were randomly selected and divided into 5 groups (n=6). Group I: normal control. II: (DN)...
This study aims to determine the prevalence of joint pain and its association with demographic, socioeconomic behavioural factors in Nepal.The was a national cross-sectional population-based study.We used most recent nationally representative health survey, The WHO STEPwise approach surveillance (STEPS) 2019 from all seven provinces Nepal including both urban rural areas.The participants were men women aged 15-69 years, who usual residents households for at least 6 months have stayed night...