Kalyan Sapkota

ORCID: 0000-0003-4011-6430
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About
Contact & Profiles
Research Areas
  • COVID-19 and Mental Health
  • COVID-19 Pandemic Impacts
  • Venomous Animal Envenomation and Studies
  • COVID-19 epidemiological studies
  • SARS-CoV-2 and COVID-19 Research
  • Hemoglobinopathies and Related Disorders
  • Rabies epidemiology and control
  • COVID-19 Clinical Research Studies
  • Child Nutrition and Water Access
  • Iron Metabolism and Disorders
  • Pregnancy and preeclampsia studies
  • Prostate Cancer Treatment and Research
  • Pleural and Pulmonary Diseases
  • COVID-19 diagnosis using AI
  • Erythropoietin and Anemia Treatment
  • Growth Hormone and Insulin-like Growth Factors
  • Bone health and osteoporosis research
  • Dialysis and Renal Disease Management
  • Hip and Femur Fractures
  • SARS-CoV-2 detection and testing
  • Health and Well-being Studies
  • Chronic Kidney Disease and Diabetes
  • Poisoning and overdose treatments
  • Antibiotic Use and Resistance
  • Bioactive Natural Diterpenoids Research

Chitwan Medical College
2017-2024

National Academy of Medical Sciences
2024

Iowa State University
2020

Bentley University
2020

University of Iowa
2020

Boston University
2020

Abstract Background COVID-19 is a viral respiratory disease that was recently recognized in humans. The number of cases has been gradually increasing Nepal. objective this study to evaluate knowledge, attitude and practice regarding among healthcare workers Chitwan, one the districts located central Methods It cross-sectional conducted from various health institutions Chitwan district A self-reported questionnaire circulated online. Bivariate analyses were done using Spearman’s correlation...

10.21203/rs.3.rs-26774/v1 preprint EN cc-by Research Square (Research Square) 2020-05-08

Background: The cases of Coronavirus disease-2019 (COVID-19) has been gradually increasing in Nepal. objective this study was to evaluate knowledge, attitude and practice regarding COVID-19 among healthcare workers Chitwan, one the districts located central Nepal.
 Methods: It a descriptive, cross-sectional study, conducted from differ­ent health institutions over span two weeks 1st April, 2020 till 14th 2020. Bivariate analyses scores were done with different variables using...

10.3126/jcmc.v10i3.32064 article EN cc-by-nc Journal of Chitwan Medical College 2020-10-13

Introduction: The rapid increase in the cases of childhood obesity and overweight its potential to pose other non-communicable diseases has made it a global public health issue. Urbanisation changing lifestyles also threat disease Nepal, but prevalence such Nepal is still not known according method recommended by World Health Organization for children's overweight. This study aimed find out abnormal high body mass index among adolescents secondary schools. Methods: A descriptive...

10.31729/jnma.8405 article EN cc-by Journal of Nepal Medical Association 2024-01-02

Coronavirus disease (COVID-19) outbreak, caused by the most recently discovered coronavirus, is currently affecting a large population across globe. World health organization (WHO) has already declared COVID-19, pandemic, and world fighting to contain COVID-19 outbreak. Nepal taken several preventive measures control coronavirus However, some additional steps are needed prevent community transmission of disease. This brief communication discusses government actions provides recommendations...

10.3126/jpahs.v7i1.28879 article EN Journal of Patan Academy of Health Sciences 2020-05-08

Background: The cases of Coronavirus disease-2019 (COVID-19) has been gradually increasing in Nepal. objective this study was to evaluate knowledge, attitude and practice regarding COVID-19 among healthcare workers Chitwan, one the districts located central Methods: It a descriptive, cross-sectional study, conducted from differ­ent health institutions over span two weeks 1st April, 2020 till 14th 2020. Bivariate analyses scores were done with different variables using appropriate tests SPSS...

10.54530/jcmc.221 article EN cc-by-nc Journal of Chitwan Medical College 2020-09-27

Background: Pregnant and breastfeeding women are more susceptible to viral infection in the year 2020 they have face COVID-19 pandemic. Since, no successful treatment vaccine has been developed so far, efforts enhance knowledge, attitudes, practice of public, especially high-risk groups like pregnancy postpartum period crucial manage pandemic.
 Objective To analyze attitude, hospital experience regarding among post-partum mothers at a tertiary care center Nepal Method The data...

10.3126/kumj.v18i2.32938 article EN Kathmandu University Medical Journal 2020-11-17
Janak Koirala Pradip Gyanwali Robert B. Gerzoff Saroj Bhattarai Bipin Nepal and 95 more Rekha Manandhar Runa Jha Sanjeev Sharma Yuba Raj Sharma Anup Bastola Holly Murphy Subhash Prasad Acharya Prabhat Adhikari Manita Rajkarnikari Karishma Malla Vaidya Chhabi L. Panthi Bihungum Bista Grishma Giri Shambhu Aryal Suman Pant Akritee Pokharel Shristi Karki Sangita Basnet Bhagawan Koirala Meghnath Dhimal Roshan Kumar Jha Anil Shrestha Ashesh Dhungana Shreejana Shrestha Sarita Pandey Sangita Shakya Philip S Ranjit Sunil Dhungel Devendra Bhattarai Sumitra Gautam Pramod Poudel Kalyan Sapkota Khagendra J Shah Rajesh Kumar Mandal Rajan Kumar Pandey Sumit Prajapati Arif Hussain Shakuntala Gupta Roshan Chhetri Krishna Pokharel Kala Thapa Shital Adhikari Gopendra Prasad Deo Basanta Gauli Pukar Ghimire Bishnu P. Regmi Ram B Gurung Rajeev Shrestha Dipesh Tamrakar Sushil Khanal Upasana Acharya Suhail Sapkota Reema Shrestha Milesh Jung Sijapati Smriti Koirala Suraj Bajracharya Deepak Sigdel Den P Acharya Sudarshan Chhetri Prashanta Acharya Hari Prasad Panthi Ashesh Dhungana Achyut Raj Karki R. K. Singh Uday Narayan Singh Rakesh Tiwari Asraf Hussain Rupesh Shah Parwez Alam Ansari Diptesh Aryal Sanjit K Shrestha Kanchan Koirala Kiran Kumar KC B Acharya Shyam Kumar BK Sumit Kumar Pandey Suraj Gupta Deepa Shakya Yunima Sapkota Anju Adhikari Bishwanath Koirala Bipin Karki Yuba Raj Sharma Bimal Pandey Buddhi S Lamichhane Sanjay Shrestha Sher Bahadur Kamar Ashok Chaudhary Jagdish Chandra Joshi Kunjang Sherpa Reeju Manandhar Chiranjibi Pant Rinku Joshi Anup Bastola Bimal Sharma Chalise

Abstract Background Convalescent plasma therapy (CPT) and remdesivir (REM) have been approved for investigational use to treat coronavirus disease 2019 (COVID-19) in Nepal. Methods In this prospective, multicentered study, we evaluated the safety outcomes of treatment with CPT and/or REM 1315 hospitalized COVID-19 patients over 18 years 31 hospitals across was administered moderate, severe, or life-threatening infection. severe infections who were at high risk progression clinical worsening...

10.1093/ofid/ofab391 article EN cc-by-nc-nd Open Forum Infectious Diseases 2021-08-01

The safety and efficacy of ondansetron has led to its wider clinical use this could increase unusual serious adverse events. Therefore, we emphasize the need for cautious beware prepare

10.1002/ccr3.4110 article EN Clinical Case Reports 2021-05-01

There are very few researches from Nepal that have evaluated clinical profile of end stage renal disease patients. Our main objective was to study the patients, who were under maintenance hemodialysis for at least three months duration in two dialysis centers located Chitwan Nepal.This a descriptive, cross-sectional conducted among 138 undergoing government Chitwan, Nepal.Among patients our study, 42 (30.4%) had diabetic nephropathy and 11 (8%) hypertensive as leading causes disease; however...

10.33314/jnhrc.v19i3.3531 article EN Journal of Nepal Health Research Council 2021-12-10

The thyroid gland plays a vital role in body metabolism, through the production of hormones, which are known to have important actions controlling many human reproductive functions. Thyroid dysfunctions most prevalent women during their fertile years (15 - 35) and dysfunction pregnancy is associated with higher risk neonatal complications. Routine screening can help identify treat disorder early prevent its complication. A hospital based observational study on 400 pregnant was conducted...

10.1016/j.eprac.2024.03.086 article EN other-oa Endocrine Practice 2024-05-01

Background: Thyroid dysfunctions are most prevalent in women during their fertile years (15 - 35) and thyroid dysfunction pregnancy is associated with higher risk of neonatal complications. Routine screening can help to identify treat the disorder early prevent its complication. Methods: A hospital based observational study on 400 pregnant was conducted tertiary level Nepal. Participants abnormal functions were regularly followed up till outcome. Results: Among cases, 45.3% respondents age...

10.3126/jdean.v8i1.76649 article EN Journal of Diabetes and Endocrine Association of Nepal 2024-12-31

Background Prostate specific antigen (PSA) is a serine protease produced by the prostate epithelium and per urethral glands in male. Serum PSA elevation occurs as result of disruption normal prostatic architecture that allows to diffuse into tissue gain access circulation. Prostatic hyperplasia progressive condition characterized enlargement accompanied lower urinary tract symptoms (LUTS). MethodsThe objective investigate correlation between serum levels trans abdominal USG volume clinically...

10.3126/jcmsn.v20i1.61158 article EN cc-by-nc-nd Journal of College of Medical Sciences-Nepal 2024-03-29

We aimed to estimate the cost of snakebite and its impact on economy snakebite-affected households in southern Nepal. conducted cross-sectional prospective studies confirmed cases at two hospitals south central southwestern Nepal during May October 2020. estimated economic affected by evaluating direct indirect costs for treatments opportunity patients attendants (household members or relatives). included 553 snakebites that caused 185 envenomings (34%), resulting 15 deaths (case fatality...

10.4269/ajtmh.24-0399 article EN American Journal of Tropical Medicine and Hygiene 2024-11-19

Background: Shock, particularly septic shock, is a critical medical condition characterized by inadequate blood flow, leading to multi-organ failure and high mortality rates. Traditional treatment includes fluid resuscitation antibiotic therapy, but advancements in understanding management are needed. This study aims evaluate the rationale use of noradrenalin vasopressin patients with specifically focusing on their effects pressure. Methods: Conducted as prospective observational at tertiary...

10.18203/2319-2003.ijbcp20243842 article EN International Journal of Basic & Clinical Pharmacology 2024-12-24

ABSTRACT
 Background: Pleural effusion occurs when there is disequilibrium between the quantity of fluid entering and leaving pleural space. The objective study was to investigate association underlying medical conditions as heart failure, pneumonia, malignancies clinical presentations laboratory findings all those patients admitted Bharatpur Hospital during period last 1year.
 Methods: Retrospective data from September 2022 2023 cases diagnosed with will be taken. Altogether 120...

10.3126/jnhls.v2i2.60752 article EN Journal of National Heart and Lung Society Nepal 2023-12-31

Background: Rising number of End Stage Renal Disease patients is a great economic burden because its high cost and lifelong treatment need. Target hemoglobin in dialysis maintained through iron supplement, Erythropoietin stimulating agents, Blood products transfusions other correctable causes. Large Hemoglobin fluctuation such related to decreased survival. The aim this study was relate variability with mortality patients. Methods: This cross sectional observational carried out 104...

10.3126/jnhls.v2i2.60357 article EN Journal of National Heart and Lung Society Nepal 2023-12-31

Background: Ageing is associated with various physiological and pathological changes including Mental Health. health a neglected problem in Nepal which underdiagnosed undertreated, especially among elderly population. However, Depression people the most common mental worldwide Nepal, Limited research has been conducted. Thus, study aimed to assess prevalence factors of depression admitted tertiary level hospital, Nepal. Methods: Descriptive cross-sectional design was used where 330 patients...

10.3126/jnhls.v2i2.59823 article EN Journal of National Heart and Lung Society Nepal 2023-12-31

Esophageal varices are one of the most serious consequence portal hypertension in patients with liver diseases If undetected or left untreated, it can result massive upper gastrointestinal bleed and be fatal. Therefore, a timely detection management cirrhotic patient is must. Several studies have evaluated possible noninvasive markers esophageal to reduce number unnecessary endoscopies cirrhosis but without varices. Endoscopic surveillance expensive for health system uncomfortable patients....

10.55530/ijmbiosnepal.v2i1.23 article EN cc-by-nc International Journal of Medicine and Biomedical Sciences 2017-01-31

Introduction: COVID-19 poses a great challenge to the global health system. The nurses worked in COVID ward and fever clinic act as gatekeepers care system public response epidemic. consequences of lockdown, quarantine pandemic has not only caused physical sufferings but also affected mental around globe. This study aimed assess psychological impact associated factors 19 among working different level hospital at Bharatpur Municipality Chitwan, Nepal.
 Methods: A cross-sectional...

10.3126/jcmsn.v17i2.33668 article EN cc-by-nc-nd Journal of College of Medical Sciences-Nepal 2021-06-30

Intestinal parasitosis is one of the major public health and socio-economic problems in Nepal. It ranked among top10 morbidities Fecal samples were collected from patients attending to different hospitals privatelaboratories throughout Myagdi district. A total 985 participants included study. The age ranged 1to 86 years. Commonly affected group was below 15 Male female ratio 1.3:1. general prevalence infection with types intestinal parasites 14.7% (145). fecal examination revealed helminths...

10.55530/ijmbiosnepal.v2i2.26 article EN cc-by-nc International Journal of Medicine and Biomedical Sciences 2017-03-31

Recurrent or persistent positivity of SARS-CoV-2 RNA in clinically recovered COVID-19 patients have been reported worldwide. However, replication competent live viruses were not beyond two to three weeks from onset symptoms mild severe cases COVID-19. End stage renal disease is characterized by uremia induced immune dysfunction that increases the risk infectious diseases including The clinical implications recurrent persistently positive immunocompromised are difficult be generalized...

10.31729/jnma.5249 article EN cc-by Journal of Nepal Medical Association 2020-11-22

Background Poisoning is a major cause of death in young adults. The epidemiological factors such as geography, occupation, literacy rate can influence the clinical presentation and outcome poisoning patients. has significant impact on economic social life individuals. 
 Objective main objective this study an effort to evaluate characteristic cases identify reasons for Intensive Care Unit (ICU) admission. Method This was prospective observational at Bharatpur Hospital ICU over period one...

10.3126/kumj.v18i1.33361 article EN Kathmandu University Medical Journal 2020-01-06

Background: Snake bites are well-known medical emergencies requiring hospital admission. Krait and Cobra common snakes leading to envenomation in Nepal. Timely identification of the leads prompt treatment decrease morbidity mortality. We aimed study clinical profile outcome patients with snake at Bharatpur Hospital, Materials Methods: The Study was a descriptive cross-sectional conducted Department Medicine from April 2018 September 2018. admitted signs neurological, hematological, local or...

10.52403/ijhsr.20220728 article EN International Journal of Health Sciences and Research 2022-07-20
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