- Streptococcal Infections and Treatments
- Acute Myocardial Infarction Research
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Public Health and Nutrition
- Venous Thromboembolism Diagnosis and Management
- Infective Endocarditis Diagnosis and Management
- Pericarditis and Cardiac Tamponade
- Pulmonary Hypertension Research and Treatments
- Pneumothorax, Barotrauma, Emphysema
- Heart Failure Treatment and Management
- SARS-CoV-2 and COVID-19 Research
- Health and Wellbeing Research
- Education and Learning Interventions
- Cardiovascular Effects of Exercise
- Coronary Interventions and Diagnostics
- Long-Term Effects of COVID-19
- Diverse Scientific Research Studies
- Biomarkers in Disease Mechanisms
- COVID-19 and Mental Health
- Otolaryngology and Infectious Diseases
- Pharmacology and Nanomedicine Research
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Cardiac Valve Diseases and Treatments
Shahid Gangalal National Heart Centre
2016-2024
Invictus Medical (United States)
2024
First Affiliated Hospital of Xi'an Jiaotong University
2015
Abstract Background Convalescent plasma therapy (CPT) and remdesivir (REM) have been approved for investigational use to treat coronavirus disease 2019 (COVID-19) in Nepal. Methods In this prospective, multicentered study, we evaluated the safety outcomes of treatment with CPT and/or REM 1315 hospitalized COVID-19 patients over 18 years 31 hospitals across was administered moderate, severe, or life-threatening infection. severe infections who were at high risk progression clinical worsening...
Background and Aims: Incidence of ST-elevation myocardial infarction (STEMI) is increasing in Nepal. We aim to describe the presentation, management, complications, outcomes patients admitted with a diagnosis STEMI Shahid Gangalal National Heart Centre (SGNHC), Nepal.
 Methods: Centre-ST-elevation registry (SGNHC-STEMI) was cross sectional, observational, registry. All who were from January 2018 December included.
 Results: In this registry, 1460 out 1486 attended emergency...
Background and Aims: Acute ST elevation myocardial infarction (STEMI) is often present in old populations. STEMI young has significantly increased recent years. We aim to study the conventional risk factors, clinical presentation, management outcome of patients.Methods: Medical records all patients (aged less than 45 years), who were admitted our hospital with diagnosis treated between 1st July 2015 30th June 2016, retrospectively reviewed. Demographics, recorded.Results: There total 1211...
Background and Aims: Chronic obstructive pulmonary disease (COPD) is highly prevalent in the Nepalese population. It associated with significant extrapulmonary effects among which cardiovascular complications are most common. Echocardiography evaluation mainly focused on right heart function a salient tool to evaluate presence of degree hypertension also identify those group patients who need more early aggressive therapy for underling lung . We aimed prospectively study diagnosed COPD...
Lipid-lowering is an important intervention to reduce cardiovascular morbidity and mortality after ST-Elevation myocardial infarction. This study aimed assess the proportion of such patients achieving guideline-directed therapeutic low-density lipoprotein cholesterol targets while on lower-range high-intensity statin treatment. a cross-sectional conducted in Shahid Gangalal National Heart Centre, tertiary cardiac center Kathmandu, Nepal, from November 2021 July 2022 among admitted acute...
Background and Aims: The prevalence of risk factors for cardiovascular diseases is globally increasing leading to the increase in mortality morbidity due diseases. objective this study assess among residents urban community Kathmandu municipality.Methods: By using simple random sampling method, we selected 130 participants aged 18 years or above, from voters list ward no.22 Kathmandu. Male less than 45 female 55 were grouped as young age group which included total 80 (61.5%) rest old group....
Background and Aims: Pericardial effusion is a common finding in every day clinical practice. It caused by range of local systemic disorders, many which could be idiopathic. effusions can acute or chronic. The etiology pericardial varies different parts the world related to relative prevalence diseases.
 Methods: This retrospective study where data from all cases admitted with SGNHC January 2021 December 2022 were included. Altogether 218 diagnosed established Echocardiograpy Evaluation...
Introduction: Patients with Atrial fbrillation (AF) are at fivefold higher risk for Ischemic stroke than in the general population. Although current therapeutic guidelines recommend use of anticoagulants thromboembolic prophylaxis patients nonvalvular AF (NVAF) additional factor(s) stroke, global registry data show non-adherence to management diferent regions world. The study conducted tertiary referral cardiac center Nepal addressing profle based on scores and antithrombotic agents NVAF...
Background and Aims: Prosthetic valve thrombosis is a life- threatening complication of post-valve replacement surgeries. A number patients present with thrombotic complications mainly due to poor anticoagulation status irregular INR checkup especially from remote areas Nepal. Our aim was study the clinical profile management prosthetic in our center. Methods: prospective observational 45 (July 2017 – Jun 2019) admitted at Shahid Gangalal National Heart Centre, diagnosis were studied. The...
Background and Aims: Even though heart failure (HF) is a major global health problem, studies on the prevalence etiology of HF in Nepal are scant. Coronary artery disease (CAD) has been reported to be 18% presentations emergency department tertiary cardiac center Nepal1. Present study evaluated characteristics CAD with reduced ejection fraction (HFrEF) coronary angiography (CAG).
 Methods: In prospective, observational study, conducted from June 2018 May 2019, 95 patients HFrEF...
Rheumatic fever presenting late in adult beyond 25 years of age is a rare but common phenomena and noted various case reports .The diagnosis rheumatic activity based on the same modified Jones criteria for heart disease. Here we describe 49 year old male , known disease with severe aortic regurgitation post valve replacement who presented migratory polyarthritis along history preceding sore throat 2 weeks prior to this illness . He was managed high dose aspirin therapy oral penicillin after...
Background and Aims: Cardiovascular comorbidities are common in patients with COVID-19 these at higher risk of morbidity mortality. It is not known if the presence cardiovascular co-morbid conditions poses independent or whether this mediated by other factors.
 Methods: This a retrospective follow up study done Shahid Gangalal National Heart Centre (SGNHC). The main objective was to clinical profile, baseline comorbidities, outcome cardiac health care worker diagnosed COVID 19....
Background and Aims: Heart Failure (HF) with reduced Ejection Fraction (HFrEF) is defined as the clinical diagnosis of HF left ventricular ejection fraction (LVEF) ≤ 40%, also referred to systolic HF. Guideline-directed medical therapy (GDMT) has shown reduce mortality for HFrEF. We aim evaluate adherence GDMT treatment in our outpatients.
 Methods: It was a cross-sectional observational study. All patients who attended Department preventive medicine cardiac rehabilitation counseling...
Background: Proper knowledge regarding Coronary Artery Disease and their risk factors is essential for the early recognition of disease its presentation. This study was conducted to identify pattern clinical symptoms among ST-Elevation myocardial infarction (STEMI) patients. Methods: cross-sectional, observational 340 patients in inpatient Cardiology Department Shahid Gangalal National Heart Centre Nepal, from November 2020 February 2021. Baseline characteristics, factors, patterns symptoms,...
Background and Aims: ST-segment elevation myocardial infarction(STEMI), a severe form of coronary heart disease signifies total occlusion artery leading to necrosis, however about 10-20% patient’s presents with patent infarct-related on the initial angiogram. The availability reliable markers for prediction patency in is very limited.Methods: We conducted single centered retrospective study STEMI patients undergoing primary percutaneous intervention, determine how various factors such as...
Pulmonary embolism in an old patient with a history of coagulation disorder, any recent major surgeries or chronic heart lung diseases is widely reported. Also, travel by air flight distance more than 5000km BMI greater 35 kg/m2 increase risk. However, we report here, suggestive case acute pulmonary previously well male 38 years, 25.71kg/m2 without illness exacerbations.
 The presented health facility sudden onset radiating chest pain and some other nonspecific symptoms. Neither...
The prevalence of rheumatic heart disease is still significant in Nepal, especially rural areas. It an important preventable cause morbidity and mortality children young adults. Diagnosis acute fever based on clinical, laboratory, echocardiographic criteria. management criteria need to be locally relevant practical our context for implementation at the national level. Cardiac Society Nepal initiated development consensus document with aim providing a reasonable format diagnostic management....