- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Global Public Health Policies and Epidemiology
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Streptococcal Infections and Treatments
- Cardiovascular Function and Risk Factors
- COVID-19 diagnosis using AI
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Cardiovascular and Diving-Related Complications
- Healthcare Systems and Public Health
- Congenital Heart Disease Studies
- Cardiac Imaging and Diagnostics
- Biomarkers in Disease Mechanisms
- Ultrasound in Clinical Applications
- Cardiac tumors and thrombi
- Dietary Effects on Health
- Pain Management and Treatment
- Health and Wellbeing Research
Shahid Gangalal National Heart Centre
2013-2024
Kathmandu University
2021-2024
Invictus Medical (United States)
2024
National Academy of Medical Sciences
2021-2024
Dhulikhel Hospital
2022-2023
University of Calgary
2018
Antimicrobial resistance (AMR) is a global health challenge driven by the misuse and overuse of antibiotics. Two key initiatives taken World Health Organization (WHO) to promote rational antibiotic use address AMR include updating Essential Medicines List (EML) implementing Access, Watch Reserve (AWaRe) classification. This study aimed assess prescribing patterns at tertiary care teaching hospital. A 12-month observational, prospective was conducted on indoor patients from Medicine, Surgery,...
Background and Aims: Rheumatic Fever, Heart Disease Congenital disease are the most common cardiac problems in school children. Prior studies have reported different prevalence rate of among groups population Nepal. The aim this study was to estimate children Kathmandu Valley Methods: Cardiac screening 34,876 from 115 randomly selected public schools two cities (Kathmandu Lalitpur) done. Cases with abnormal findings auscultation underwent echocardiography diagnosis confirmed. Results: noted...
Carotid intima-media thickness (CIMT) and carotid plaques are non-invasive surrogate markers of early evaluation coronary artery disease (CAD) sub clinical atherosclerosis. The objective the study was to evaluate CIMT in less than 45 years old Nepalese patients with angiographically proven CAD.A total 54 documented CAD at age were enrolled. confirmed by angiography. Demographic profile obtained. High resolution B-mode ultrasound used detect plaques.The population included 44 males 10...
Figure 1.Right anterior oblique cranial projection of the right coronary artery (RCA) showing a second left descending (LAD) arising from proximal RCA and leading to interventricular septum, with septal branches totally occluded third diagonal branch.
Background Studies evaluating potential differences in normal cardiac dimensions and body mass indices of various ethnic populations using 2D echocardiography have reported variations based on gender ethnicity. Currently, accepted echocardiographic reference values are from US studies, the limited information is available Nepalese population. The purpose this study was to derive population-based for two-dimensional (2D) guided M-mode left ventricular adult that can be applied epidemiologic...
Abstract Background Cardiovascular diseases (CVDs) are the leading cause of deaths and disability in Nepal. Health systems can improve CVD health outcomes even resource-limited settings by directing efforts to meet critical system gaps. This study aimed identify Nepal’s gaps prevent manage CVDs. Methods We formed a task force composed government non-government representatives assessed performance across six building blocks: governance, service delivery, human resources, medical products,...
Smoking, diabetes mellitus, hypertension, and dyslipidemia are labelled as conventional risk factors for coronary artery disease. Prevalence of these varies across populations. This study aimed to assess the prevalence in patients, who were discharged from our hospital, with diagnosis ST elevation myocardial infarction.Medical records 495 infarction patients centre between January 2012 December retrospectively reviewed evaluate factors.Clear dominance (75%) male was seen. Inferior wall...
Background and Aims: Incidence of ST-elevation myocardial infarction (STEMI) is increasing in Nepal. We aim to describe the presentation, management, complications, outcomes patients admitted with a diagnosis STEMI Shahid Gangalal National Heart Centre (SGNHC), Nepal.
 Methods: Centre-ST-elevation registry (SGNHC-STEMI) was cross sectional, observational, registry. All who were from January 2018 December included.
 Results: In this registry, 1460 out 1486 attended emergency...
Background and Aims- Reperfusion therapy is indicated for patient with acute ST Elevation Myocardial Infarction. Several randomized trials meta-analyses have shown that Primary Percutaneous Coronary Intervention better than thrombolysis. Our aim was to determine the outcomes of in Shahid Gangalal National Heart Centre, Nepal. Methods- Medical records 212 from March 2007 2012 were retrospectively reviewed. The primary end point in-hospital mortality secondary points 30 day long term...
Background and Aims: Prosthetic valve thrombosis remains a major complication of replacement surgeries in Nepal. A number patients present with thrombotic complications mainly due to poor anticoagulation status irregular INR checkup at the remote areas Thrombolysis is preferred method management stuck financial issues . We aimed retrospectively study clinical profile trends prosthetic valveMethods: one year retrospective data 23 (Jan 2015 - Jan 2016) admitted diagnosis were studied. The...
Background and Aims: Acute ST elevation myocardial infarction (STEMI) is often present in old populations. STEMI young has significantly increased recent years. We aim to study the conventional risk factors, clinical presentation, management outcome of patients.Methods: Medical records all patients (aged less than 45 years), who were admitted our hospital with diagnosis treated between 1st July 2015 30th June 2016, retrospectively reviewed. Demographics, recorded.Results: There total 1211...
Background and Aim: Percutaneous balloon mitral valvotomy is well established as safe effective procedure for patients with stenosis due to Rheumatic Heart Disease. There are some retrospective studies on safety efficacy of it in different subgroups from our centre. Our study aims assess the safety, outcome Shahid Gangalal National Centre, Kathmandu, Nepal. Methods: A Single centre, prospective was conducted July 1st 2013 June 31st 2014 All who underwent percutaneous moderate severe during...
Background and Aims: The prevalence of risk factors for cardiovascular diseases is globally increasing leading to the increase in mortality morbidity due diseases. objective this study assess among residents urban community Kathmandu municipality.Methods: By using simple random sampling method, we selected 130 participants aged 18 years or above, from voters list ward no.22 Kathmandu. Male less than 45 female 55 were grouped as young age group which included total 80 (61.5%) rest old group....
Background: Iron deficiency (ID) is a major heart failure comorbidity associated with increased mortality, worse symptoms and poorer quality of life, irrespective anaemia. In Nepal, limited data are available to permit an estimation the spectrum prevalence ID failure, which present study aimed find. Methods: A single-centre, cross-sectional, observational was conducted at tertiary care hospital in Kathmandu, Nepal. Patients meeting validated clinical criteria were included assessed for their...
Background. Nepal, currently facing a high burden of noncommunicable diseases (NCDs), including cardiovascular (CVDs), which poses the highest mortality rate in country, does not seem to have proper referral strategy. This study explored wide range factors and challenges that affect system CVD cases Nepal. Methods. In this qualitative study, we conducted face-to-face telephone interviews with purposely selected 57 key participants included 35 healthcare professionals from tertiary,...
Background: and objective: Lipid-lowering is an important intervention to reduce cardiovascular morbidity mortality in the secondary prevention of STEMI. There no study analyze use statin LDL-C treatment target attainment among STEMI patients Nepal. This aims assess patients.Methods: It was a prospective observational single-center conducted at Shahid Gangalal National Heart Centre, Kathmandu, Nepal outpatient department. An department-based survey who have lipid profile levels time...
Background: Hypertension is the leading cause of cardiovascular disease and premature death worldwide. Left ventricular hypertrophy (LVH), a measure hypertensive target organ damage in heart associated with increased morbidity, mortality development arrhythmias. This study was designed to identify more accurate ECG criteria for identifying LVH taking by echocardiography as reference. Methods: A cross sectional conducted at Shahid Gangalal National Heart Centre. total 252 patients were...
Background Severe Hypercholesterolemia, defined as low-density lipoprotein cholesterol of ≥190mg/dL (≥4.9 mmol/L), has a high risk Atherosclerotic Cardiovascular Disease and premature recurrent coronary events. Its prevalence may be 5–7% in the general population. This registry aims to provide insights into clinical profiles practice patterns among such patients treated at tertiary cardiac hospital Nepal. Methods was cross-sectional, observational, who were diagnosed with...
Background and Aim: Cardiac Magnetic Resonance (CMR) is a crucial noninvasive imaging technique for the thorough evaluation of heart in various cardiovascular conditions. The potential to offer quantitative data on cardiac perfusion function make CMR an exceptional choice providing functional morphological information about heart. We performed MR patients over period 12 months. Our aim was establish common indications diagnoses diferent age groups our population.Method: A retrospective...
Transcatheter aortic valve implantation (TAVI) has rapidly evolved in the last decade to become treatment of choice for most patients with severe stenosis. Acute coronary occlusion during TAVI is a rare and life-threatening complication high morbidity mortality rates. If considered highly likely occur, risk reassessment could favor surgical replacement. An excessive that mandates continuing transcatheter strategy requires protection techniques. Coronary techniques include; wire protection,...
Abstract Objective Multidetector computed tomography is considered a reliable, non-invasive modality for diagnosing myocardial bridging. The prevalence of bridges varies greatly based on the technique used to identify anomaly. We aimed evaluate frequency and morphological features bridging in patients who underwent ECG-gated 640 slice coronary angiography at Shahid Gangalal National Heart Centre. Methods A retrospective cross-selectional study was conducted From 1 January 2021 30 June 2021,...
Pulmonary stenosis is common and accounts for 5%–12% of all congenital heart diseases. Echocardiography the mainstay evaluating pulmonary due to its easy availability, reproducibility non-invasive nature. American Heart Association/American College Cardiology (AHA/ACC) guideline recommends balloon valvuloplasty in patients with moderate severe valvular stenosis. Due advantages over other balloons, Inoue Accura balloon, balloons especially designed Percutaneous Transluminal mitral...