A5100388541- Advanced MRI Techniques and Applications
- Pulsed Power Technology Applications
- Gyrotron and Vacuum Electronics Research
- Medical Imaging Techniques and Applications
- Physics of Superconductivity and Magnetism
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Functional Brain Connectivity Studies
- Atomic and Subatomic Physics Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Plasma Applications and Diagnostics
- Anesthesia and Sedative Agents
- ZnO doping and properties
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Advanced NMR Techniques and Applications
- Ubiquitin and proteasome pathways
- Protease and Inhibitor Mechanisms
- Cerebral Palsy and Movement Disorders
- Meat and Animal Product Quality
- Glaucoma and retinal disorders
- Cell Adhesion Molecules Research
- Synthesis and biological activity
- Traditional Chinese Medicine Analysis
- Plasma Diagnostics and Applications
University of Malaya
2025
Inner Mongolia Agricultural University
2025
Shenzhen Second People's Hospital
2023-2024
Shenzhen Institute of Information Technology
2024
NorthShore University HealthSystem
2004-2023
Jinan University
2023
Shenzhen University
2023
ZheJiang Institute For Food and Drug Control
2020-2022
Hebei Agricultural University
2022
Shenzhen Inno Translational Medicine Institute
2022
Disruption of oligodendrocyte lineage progression is implicated in the white-matter injury that occurs cerebral palsy. We have previously published a model rabbits consistent with Little known normal development perinatal rabbits. Using multidimensional approach, we defined relationship and functional maturation axons to structural selected tracts as determined by diffusion tensor imaging (DTI). Immunohistochemical studies showed late progenitors appear at gestational age 22 [embryonic day...
Most functional magnetic resonance imaging (fMRI) animal studies rely on anesthesia, which can induce a variety of drug-dependent physiological changes, including depression neuronal activity and cerebral metabolism as well direct effects the vasculature. The goal this study was to characterize anesthesia BOLD signal activity. Simultaneous fMRI electrophysiology were used measure changes in single units (SU), multi-unit (MUA), local field potentials (LFP), blood oxygenation level-dependent...
The p53 tumor suppressor protein and the MDM2 oncoprotein form a feedback-control loop that up-regulates cellular production, blocks activity, promotes decay. tsg101 was discovered as gene whose deficiency results in neoplastic transformation of NIH 3T3 cells ability to generate metastatic tumors nude mice. Its product contains domain, Ubc, characteristic catalytic domain ubiquitin conjugase (E2) enzymes but lacking an active-site cysteine crucial for activity. Here we report TSG101...
Functional inactivation of the tumor susceptibility gene tsg101 in NIH 3T3 fibroblasts results cellular transformation and ability to form metastatic tumors nude mice. The N-terminal region protein is structurally similar catalytic domain ubiquitin-conjugating enzymes, suggesting a potential role ubiquitin-mediated degradation. C-terminal TSG101 can function as repressor transcription. To investigate physiological , we generated null mutation mouse by targeting. Homozygous −/− embryos fail...
Addressing the prevalent issue of excessive fat consumption in contemporary diets, a novel method has been devised for preparation an emulsion gel enriched with healthful fatty acids which possesses superior emulsification characteristics. This innovative approach aims to serve as viable substitute content beef mince. paper evaluate effect gels, formulated primarily Chinese yam key ingredient, on properties and microstructural characteristics The findings indicate that, when proportion...
The relative contributions of the ipsilateral and contralateral cerebellar cortex deep nuclei to delay eyeblink conditioning have been debated are difficult survey entirely using typical electrophysiological lesion techniques. To address these issues, we used single-event functional magnetic resonance imaging (fMRI) in conscious rabbit visualize entire cerebellum simultaneously during sessions. Examination blood oxygenation level-dependent (BOLD) response a visual stimulus early training...
This paper presents the investigation on reflex triode (RT) virtual cathode oscillator (vircator) using a carbon fiber cathode. Experimental results show that can obviously improve electron beam quality and dramatically enhance beam-to-microwave efficiency of RT vircator. It was found increased from about 4%-6% in case stainless steel to over 10% In order understand phenomenon enhancement, experimental studies plasma formation surface were also done facility Physically, emission is...
Abstract Ferroptosis is a novel form of iron‐dependent cell death that involved in arsenic‐induced toxicity. Realgar an arsenic‐containing Chinese medicine, which can result nephrotoxicity because long‐term exposure. However, it remains scientifically unknown whether inducer ferroptosis the kidney. This study investigated role Realgar‐induced kidney toxicity mice. ICR mice were exposed to for 28 days, and HK2 cells presence or absence treatment with ferrostatin‐1, inhibitor. The...
To reduce the dimensions of relativistic backward wave oscillators (RBWOs) operating in low frequency regime less than 2 GHz, theory transversal and longitudinal mode selections are introduced this paper. The selection is achieved using property “surface wave” coaxial slow-wave structure (SWS) to excite quasi transverse electromagnetic (quasi-TEM) without higher magnetic (TM) modes it proved that SWS may decrease dimension sections. In addition, S-parameter method employed investigate...
This paper presents the effects of cathode materials on oscillation mode a virtual oscillator (vircator). In case stainless steel cathode, an hopping appeared with two separate frequencies. Interestingly, vircator using carbon fiber exhibited almost unchanged microwave frequency throughout pulse. To understand this phenomenon, several parameters are compared, including diode voltage, accelerating gap, emitting area, and beam uniformity. It was found that flat-top voltage relatively stable...
Militarine, a natural glucosyloxybenzyl 2-isobutylmalate, isolated from Bletilla striata, was reported with prominent neuroprotective effect recently. The limited information on the metabolism of militarine impedes comprehension its biological actions and pharmacology. This study aimed to investigate metabolite profile distribution in vivo, which help clarify action mechanism further. A total 71 metabolites (57 new metabolites) rats were identified systematic method by ultra-high-performance...
Background Signal regulate protein α (SIRPα) is involved in many functional aspects of monocytes. Here we investigate the role SIRPα regulating β2 integrin-mediated monocyte adhesion, transendothelial migration (TEM) and phagocytosis. Methodology/Principal Findings THP-1 monocytes/macropahges treated with advanced glycation end products (AGEs) resulted a decrease expression but an increase integrin cell surface adhesion to tumor necrosis factor-α (TNFα)–stimulated human microvascular...
Senecavirus A (SVA), also known as Seneca Valley virus, is a recently discovered picornavirus that can cause swine vesicular disease, posing great threat to the global industry. It replicate efficiently in cells, but molecular mechanism remains poorly understood. This study determined host's differentially expressed proteins (DEPs) during SVA infection using dimethyl labeling based on quantitative proteomics. Among DE proteins, DDX21, member of DEAD (Asp-Glu-Ala-Asp)-box RNA helicase (DDX)...
Abstract Millions of children undergo general anesthesia each year, and animal human studies have indicated that exposure to at an early age can impact neuronal development, leading behavioral learning impairments manifest later in childhood adolescence. Here, we examined the effects isoflurane, a commonly-used anesthetic, which was delivered newborn rabbits. Trace eyeblink classical conditioning used assess neonatal on adolescent subjects, variety MRI techniques including fMRI, MR...
We report the design and implementation of a parallel two-dimensional fast Fourier transform (2D FFT) algorithm on Field Programmable Gate Array (FPGA) for real-time MR image processing. Although number architectures 2D FFT hardware processors have been reported, these generic or IP cores are not always effective processing MRI data. The key feature our is that customized solely applications. demonstrate by considering unique features data streams, we were able to develop implement...