A5042014899- Calcium Carbonate Crystallization and Inhibition
- Bone Tissue Engineering Materials
- Advanced Photocatalysis Techniques
- Protein Interaction Studies and Fluorescence Analysis
- Drug Transport and Resistance Mechanisms
- Crystallization and Solubility Studies
- Endodontics and Root Canal Treatments
- Computational Drug Discovery Methods
- Quantum Dots Synthesis And Properties
- Advanced oxidation water treatment
- Cholinesterase and Neurodegenerative Diseases
- Seaweed-derived Bioactive Compounds
- CO2 Sequestration and Geologic Interactions
- Iron oxide chemistry and applications
- nanoparticles nucleation surface interactions
- Supercapacitor Materials and Fabrication
- Hydrocarbon exploration and reservoir analysis
- Minerals Flotation and Separation Techniques
- Cephalopods and Marine Biology
- Perovskite Materials and Applications
- Nanomaterials for catalytic reactions
- Diatoms and Algae Research
- TiO2 Photocatalysis and Solar Cells
- Bone and Dental Protein Studies
- Chemical synthesis and alkaloids
Weizmann Institute of Science
2024-2025
Indian Institute of Technology Guwahati
2019-2024
In the proposed work, complexation of bioactive flavonoid luteolin with hen egg white lysozyme (HEWL) along its inhibitory influence on HEWL modification has been explored help multi-spectroscopic and computational methods. The binding affinity observed to be moderate in nature (in order 104 M-1) static quenching mechanism was found involved fluorescence process. constant (Kb) shows a progressive increase temperature from (4.075 ± 0.046 × at 293 K (6.962 0.024 313 under experimental...
Abstract Transient amorphous phases are known as functional precursors in the formation of crystalline materials, both vivo and vitro. A common route to regulate calcium carbonate (ACC) crystallization is via direct interactions with negatively charged macromolecules. However, a less explored phenomenon that can influence such systems electrostatically driven Ca‐macromolecule dense phases. In this study, it shown how condensates form liquid–liquid phase separation (LLPS) be used control...
Contemporary literature documents extensive research on common causative mechanisms, pathogenic pathways and dual effective remedies for Alzheimer's disease (AD) Type 2 diabetes mellitus (T2DM). Tolbutamide (TBM), chlorpropamide (CPM), glyburide (GLY) are three sulfonylurea antidiabetic drugs of different generations. All these were found to exhibit moderate strong inhibitory efficiency the neurotransmitter degrading enzyme acetylcholinesterase (AChE) with GLY (IC50 = 0.74 ± 0.02 μM) being...
Biomineralized vaterite-based synthesis of the perovskite CaMnO<sub>3</sub> for effective photocatalytic dye degradation.
Detailed study on the formation of monohydrocalcite as well modulation CaCO 3 phase and morphology.
Abstract Synthesis of surface modified quantum dots (QDs) having potential biological activities are great important in biomedicinal chemistry. Here, we have synthesized mercapto propanoic acid (MPA) and thiolactic (TLA) coated water soluble cadmium selenide (CdSe) QDs activity. Dispersion into a fluid can form protein corona. Hence, the binding CdSe with carrier protein, human serum albumin (HSA) been executed using spectroscopic methods. The affinity order QDs‐HSA complexes were found 10 5...
Abstract Inorganic minerals that form via regulated biological processes exhibit remarkable properties. This is due to the involvement of macromolecules control biomineralization. Even though interactions these biopolymers with solid mineral phases are intensely studied, not much known about their in preceding steps intracellular transport building blocks. In this work, model system coccolith calcite crystallization utilized address role mineral‐associated polysaccharides calcium ions....
Silica polymerization from its soluble monomers is fundamental to many chemical processes. Although industrial methods require harsh conditions and concentrated precursors, biological silica precipitation occurs under ambient dilute solutions. The hallmark of biosilica the presence amine-rich organic macromolecules, but their functional role remains elusive. Here, we show a pH-dependent stimulatory effect such polyamines on polymerization. Notably, this process decoupled saturation degree,...
Despite being the second most abundant protein in blood plasma, reports on interaction of drugs with fibrinogen (FIB) are relatively scarce. The effect FIB therapeutic potency four FDA-approved Alzheimer's disease drugs, namely, tacrine (TAC), donepezil (DON), eserine (ESE), and huperzine (HUP), was investigated through a combination different vitro silico experiments. efficiency inhibiting activity acetylcholinesterase (AChE) significantly reduced presence FIB. This even found to be more...
In recent times, to address the increasing threat posed by wastewater discharge from industries polluted with toxic contaminants, advanced oxidation processes (AOPs) have been adopted. this work, we tried improve performance of magnetite (Fe 3 O 4 ) nanoparticles when subjected as catalysts in Fenton-like involving dye-degradation. vitro, biomineralized vaterite synthesized a template-directed method was used solid support for Fe nanoparticles, and composite catalyst initially oxidize H 2...