- Spine and Intervertebral Disc Pathology
- Management of metastatic bone disease
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Head and Neck Surgical Oncology
- Spinal Hematomas and Complications
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer Treatment and Pharmacology
University Hospital Cologne
2022-2024
University of Cologne
2022-2024
Background: Adequate assessment of spinal instability using the neoplastic score (SINS) frequently guides surgical therapy in epidural osseous metastases and subsequently influences neurological outcome. However, how to surgically manage ‘impending instability’ at SINS 7–12 most appropriately remains uncertain. This study aimed evaluate necessity instrumentation patients with regards Methods: We screened 683 treated our interdisciplinary spine center. The preoperative was assessed determine...
Background and Objectives: Prolonged bed rest after the resection of spinal intradural tumors is postulated to mitigate development cerebrospinal fluid leaks (CSFLs), which one feared postoperative complications. Nonetheless, empirical evidence supporting this conjecture remains limited requires further investigation. The goal study was investigate whether prolonged lowers risk CSFL tumors. primary outcome rate in each cohort. Materials Methods: To validate hypothesis, we conducted a...
Cerebral infarction is a significant cause of morbidity and mortality related to microsurgical clipping intracranial aneurysms. The objective this study was determine the impact aneurysm shape neck configuration on cerebral after surgery.
Surgical treatment is an integral component of multimodality management metastatic spine disease but must be balanced against the risk surgery-related morbidity and mortality, making tailored surgical counseling a clinical challenge. The aim this study was to investigate potential predictive value preoperative performance status for outcome in patients with spinal metastases.
Background Cerebrospinal fluid leakage (CSFL) following spinal durotomy can lead to severe sequelae. However, while several studies have investigated accidental durotomies, the risk factors and influence of clinical management in planned durotomies remain unclear. Methods We performed a retrospective analysis all patients who underwent intradural surgery at our institution between 2010 2020. Depending on occurrence CSFL, were dichotomized compared with respect patient case-related variables...
Background: Surgical decompression (SD) with and without posterior stabilization followed by radiotherapy is an established treatment for patients metastatic spinal disease epidural cord compression (ESCC). This study aims to identify risk factors occurrence of neurologic comprise resulting from local recurrence. Methods: All who received surgical at our center between 2011 2022 were included in this study. Cases evaluated tumor entity, technique (decompression, hemilaminectomy, laminectomy,...
Background: Surgical decompression (SD) followed by radiotherapy (RT) is superior to RT alone in patients with metastatic spinal disease epidural cord compression (ESCC) and neurological deficit. For without deficit low- intermediate-grade intraspinal tumor burden, data on whether SD beneficial are scarce. This study aims investigate the outcome of deficit, a intermediate-ESCC, who were treated or SD. Methods: single-center, multidepartment retrospective analysis includes for metastases from...
Background: Surgical decompression (SD), with or without posterior stabilization followed by radiotherapy, is an established treatment for patients metastatic spinal disease epidural cord compression (ESCC). This study aims to identify risk factors occurrence of neurological compromise resulting from local recurrence. Methods: All who received surgical at our center between 2011 and 2022 were included in this study. Cases evaluated tumor entity, technique (decompression, hemilaminectomy,...
Endovascular therapy of ruptured aneurysms is regularly accompanied by periprocedural heparinization and requires the use antiplatelets in more complex cases. This raises concerns regarding increased bleeding risks case frequently required ventriculostomy. The aim this study was to analyze risk factors for ventriculostomy-related intracranial hemorrhages (VS-ICH) endovascular or surgical treatment with a focus on antithrombotic therapy. In retrospective analysis, we included patients...
Abstract Introduction : Endovascular therapy of ruptured aneurysms is regularly accompanied by periprocedural heparinization and requires the use antiplatelets in more complex cases. This raises concerns regarding increased bleeding risks case frequently required ventriculostomy. The aim this study was to analyze risk factors for ventriculostomy-related intracranial hemorrhages (VS-ICH) endovascular or surgical treatment with a focus on antithrombotic therapy. Materials Methods In...