A5086891607- Microplastics and Plastic Pollution
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Nanoparticles: synthesis and applications
- Neuroendocrine regulation and behavior
- biodegradable polymer synthesis and properties
- Pharmaceutical and Antibiotic Environmental Impacts
- Long-Term Effects of COVID-19
- Marine Biology and Environmental Chemistry
- Occupational and environmental lung diseases
- Zebrafish Biomedical Research Applications
- Environmental Toxicology and Ecotoxicology
- Recycling and Waste Management Techniques
- Effects and risks of endocrine disrupting chemicals
- COVID-19 and healthcare impacts
- Reflective Practices in Education
- Tryptophan and brain disorders
- Gut microbiota and health
- Cancer-related Molecular Pathways
- Advanced Breast Cancer Therapies
- Metal-Organic Frameworks: Synthesis and Applications
- Aquaculture disease management and microbiota
- SARS-CoV-2 detection and testing
- Bioactive Compounds in Plants
- Invertebrate Immune Response Mechanisms
Union Hospital
2023-2025
Huazhong University of Science and Technology
2006-2025
Jinhua Polytechnic
2025
Zhejiang University
2022-2024
Hubei Provincial Hospital of Traditional Chinese Medicine
2020-2024
Wenzhou University
2022-2024
Union Hospital
2024
Hainan Medical University
2024
Integrated Chinese Medicine (China)
2019-2023
Nanjing University of Finance and Economics
2021
Background: Environmental pollution may give rise to the incidence and progression of nonalcoholic fatty liver disease (NAFLD), most common cause for chronic severe lesions. Although knowledge NAFLD pathogenesis is particularly important development effective prevention, relationship between occurrence exposure emerging pollutants, such as microplastics (MPs) antibiotic residues, awaits assessment. Objectives: This study aimed evaluate toxicity MPs residues related using zebrafish model...
The ubiquitous environmental presence of tris(2-chloroethyl) phosphate (TCEP) poses a potential threat to animals; however, little is known about its hepatotoxicity. In this study, the effects TCEP exposure (0.5 and 5.0 μg/L for 28 days) on liver health underlying toxification mechanisms were investigated in zebrafish. Our results demonstrated that led hepatic tissue lesions resulted significant alterations liver-injury-specific markers. Moreover, TCEP-exposed fish had significantly lower...
Nanoplastics (NPs) may pass through the blood-brain barrier, giving rise to serious concerns about their potential toxicity brain. In this study, effects of NPs exposure on learning and memory, primary cognitive functions brain, are assessed in zebrafish with classic T-maze exploration tasks. Additionally, reveal affecting mechanisms, impacts brain aging, oxidative damage, energy provision, cell cycle evaluated. The results demonstrate that NP-exposed takes significantly longer for first...
Abstract Lower back pain (LBP) is a common condition closely associated with intervertebral disc degeneration (IDD), causing significant socioeconomic burden. Inflammatory activation in degenerated discs involves pro-inflammatory cytokines, dysregulated regulatory and increased levels of nerve growth factor (NGF), leading to further destruction sensitization. Macrophage polarization related autophagy. Based on these pathological features, structured biomimetic nanoparticle coated...
Background Fructose 1,6-bisphosphatase 1 ( FBP1 ) has been considered as a potential prognostic biomarker in glioblastoma (GBM), and this study explored the underlying mechanism. Methods The expression effect of on prognosis GBM patients were examined applying bioinformatics analyses. After measuring normal glial cell line HEB cells, counting kit-8 (CCK-8), 5-ethynyl-2-deoxyuridine (EdU), colony formation, transwell, wound healing assay carried out to examine effects silencing proliferation...
Importance: An ongoing outbreak of COVID-19 has exhibited significant threats around the world. We found a decrease T lymphocyte subsets and an increase inflammatory cytokines hospitalized patients with in clinical practice.Methods: conducted retrospective, single-center observational study in-hospital adult confirmed Hubei Provincial Hospital traditional Chinese Western medicine (Wuhan, China) by Mar 1, 2020. Demographic, clinical, laboratory information, especially were reported. For who...
Metal nanoparticles stabilized by crystalline metal-organic frameworks (MOFs) are highly promising for green heterogeneous catalysis. In this work, in situ formed ultrafine Pd nanocatalysts with an average size of 3.14 nm have been successfully immobilized into the mesopores or defects a water-stable indium-based MOF double-solvent method and subsequent reduction. Significantly, obtained Pd@InOF-1 displays obvious satisfactory size-selective effect Suzuki-Miyaura coupling reaction between...