Background and methods: Despite continuous efforts, the increasing prevalence of resistance among pathogenic bacteria to common antibiotics has become one most significant concerns in modern medicine. Nanostructured materials are used many fields, including biological sciences While some bismuth derivatives been medicine treat vomiting, nausea, diarrhea, stomach pain, biocidal activity zerovalent nanoparticles not yet studied. The objective this investigation was analyze antimicrobial...

Epidermal growth factor (EGF) and basic fibroblast (bFGF) play an important role in extracellular matrix mineralization, a complex process required for proper bone regeneration, one of the biggest challenges dentistry. The purpose this study was to evaluate osteogenic potential EGF bFGF on dental pulp stem cells (DPSCs). Human DPSCs were isolated using CD105 magnetic microbeads characterized by flow cytometry. To induce osteoblast differentiation, cultured medium supplemented with or at low...

Helicobacter pylori is an infectious agent that colonizes the gastric mucosa of half population worldwide. This bacterium has been recognized as belonging to group 1 carcinogen by World Health Organization for role in development gastritis, peptic ulcers, and cancer. Due increase resistance antibiotics used anti-H. therapy, effective vaccine alternative great interest, which remains a challenge. Therefore, rational, strategic, efficient design against H. necessary where use most current...

Helicobacter pylori (H. pylori) infection is the most common in world and associated with various gastrointestinal pathologies, including chronic gastritis, peptic ulcers, gastric cancer. The prevalence socioeconomic conditions, this being more developing countries than developed countries. presence permanence of H. oral cavity has been reported, but its role controversial. aim study was to determine dental plaque patients periodontitis.A cross-sectional carried out Periodontal Screening...

In this paper we report on the influence of polysaccharides’ molecular structure antibacterial activity and cytotoxicity composites based silver nanoparticles (AgNPs) immobilized into carboxymethyl-cellulose (CMC). These were green synthesized from reduction ions aqueous solutions polysaccharide, using CMC with different degree substitution (DS) weight (Mw). The characterized by transmission electron microscopy (TEM), as well infrared (ATR-FTIR), ultraviolet (UV-Vis), Raman, X-ray...

This study evaluates compressive stress in teeth restored with endocrown (ECW) and build-up (BUP) using finite element analysis (FEA). Understanding distribution dental restorations is crucial for improving treatment outcomes longevity. A second lower molar was modeled Solidworks® (Version 2017). The ECW simulated nanoceramic resin, while the BUP included a core crown. Mechanical properties, including modulus of elasticity, Poisson's ratio, tensile strength were assigned to materials. Axial...

Aim: To demonstrate the antifungal and healing properties of Calendula officinalis. Methods: We included four assays: inhibition halo, germicidal test, cytotoxicity scratch test. Results: The extract at 100% 50% concentrations was effective, both presentations (Calendula officinalis infusion) exhibited no cytotoxic effects. Furthermore, infusion demonstrated a high effect without affecting morphology cell monolayer promoted fibroblastic proliferation. did not show expected results....

Dental implants are recognized as one of the most effective long-term solutions for replacement or multiple missing teeth, addressing both aesthetics and functionality. However, leading causes implant failure is peri-implant diseases. This study aims to evaluate effectiveness air polishing with sodium bicarbonate compared erythritol in reducing bacterial concentration on dental surfaces vitro. A sample twenty-four (12 JD Evolution 12 Straumann) was utilized divided follows: 10 contaminated...

The COVID-19 pandemic has significantly altered various sectors, with education being one of the most impacted. In Peru, shift from in-person to virtual was imperative due pandemic's constraints. This study investigates perception and clinical practice among final-year dentistry students at a Peruvian institution during SARS-CoV-2 pandemic. Utilizing cross-sectional design, data were collected 97 via survey assessing their experiences expectations related learning skills. Instruments...

ABSTRACT Objectives Helicobacter pylori gastric infection strongly correlates with diseases such as chronic gastritis, functional dyspepsia, and complications peptic ulcers cancer. In developing countries, systemic therapies are not usually successful due to elevated antibiotic resistance. Additionally, oral H. periodontal disease correlate treatment failures. This study aimed explore the effect of an integral therapy, comprising hygiene concomitant treatment, increase eradication...

The variability in Helicobacter pylori vacA and cagA genes has been related to the progression of gastrointestinal disease; also presence H. oral cavity associated with periodontal disease adults, but, children without dyspeptic symptoms, little is known about this. We evaluated prevalence vacA/cagA genotypes Mexican symptoms. gingival status was measured, dental plaque samples (n = 100) were taken. 38% positive for 16S rRNA gene by qPCR. A significant association between infection observed...

This study evaluated the potential antimicrobial properties of a polyguanidine (CatDex) on two oral bacteria. Chlorhexidine gluconate 1340 μ moL L −1 (CHX 0.12%) was used as control. Streptococcus mutans (S. mutans) and Porphyromonas gingivalis (P. gingivalis) were grown in BHI media. Bacterial sensitivity activity determined by minimum inhibitory concentration (MIC) Kirby-Bauer methods. To side effects, that is, toxicity, dental pulp stem cells (DPSCs) used. Fluorometric cytotoxicity...

The titanium alloy, Ti6Al4V, is used in dentistry for dental implants because of its excellent resistance to corrosion and high biocompatibility. However, periimplantitis considered the main reason treatment failure. Ti6Al4V alloy was study behavior implant applications, using an experimental arrangement three electrodes with bacteria Streptococcus gordonii Fusobacterium nucleatum, addition Ringer’s lactate as electrolytes, at 37 °C a pH 5.6. Their electrochemical studied by open circuit...

Cobalt–chromium (Co-Cr) alloys have been used in a wide variety of biomedical applications, including dental, cardiovascular, and orthopedic devices. In vitro studies shown that the mineralization cells involved osteogenesis is regulated by boron. The development new cobalt-chromium-boron (Co-Cr-B) alloy improves mechanical properties metal, such as wear resistance, meets biocompatibility requirements. Therefore, objective this study was to evaluate osteogenic differentiation assays. Human...

Culture conditions affect the production of secondary metabolites in endophytic fungi. Therefore, aim present study was to evaluate yield and anticancer antioxidant activity fungi extracts from cactus Lophocereus marginatus, under different culture conditions. The strains Penicillium citrinum, Aspergillus versicolor, Metarhizium anisopliae, Cladosporium sp. were fermented media (potato dextrose agar, Czapeck broth, malt broth), types inoculums (spore or mycelium), shaking (150 rpm static)...

Helicobacter pylori is a spiral Gram-negative bacterium associated with inflammation of the gastric mucosa, peptic ulcer, and adenocarcinoma, whose treatment has failed due to antibiotic resistance side effects. Furthermore, because there are no vaccines effective against H. , an appropriate vaccine design targeting conserved/essential genes must be identified. In present study, 50–52 kDa immunogen-derived peptide antigen sequence Met-Val-Thr-Leu-Ile-Asn-Asn-Glu (MVTLINNE) was used immunize...