A5062590360- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Maternal and fetal healthcare
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and Perinatal Health Interventions
- Fetal and Pediatric Neurological Disorders
- Neonatal Respiratory Health Research
- MRI in cancer diagnosis
- Congenital Heart Disease Studies
- Diabetes Management and Research
- Cancer Risks and Factors
- Ectopic Pregnancy Diagnosis and Management
- Pancreatic function and diabetes
- Renal and Vascular Pathologies
- Advanced Neuroimaging Techniques and Applications
- Neonatal and fetal brain pathology
- Bariatric Surgery and Outcomes
- Homicide, Infanticide, and Child Abuse
- Air Quality and Health Impacts
- Family and Patient Care in Intensive Care Units
- Urological Disorders and Treatments
- Diabetes and associated disorders
- Cardiovascular Health and Disease Prevention
University of Nottingham
2016-2025
Cardiff and Vale University Health Board
2025
Queen's Medical Centre
2008-2025
Nottingham City Hospital
2018-2024
Aintree University Hospitals NHS Foundation Trust
2023
University of Liverpool
2023
London North West Healthcare NHS Trust
2022
Cwm Taf University Health Board
2021
Prince Charles Hospital
2021
Wrightington, Wigan and Leigh NHS Foundation Trust
2021
Pregnant women with type 1 diabetes are a high-risk population who recommended to strive for optimal glucose control, but neonatal outcomes attributed maternal hyperglycaemia remain suboptimal. Our aim was examine the effectiveness of continuous monitoring (CGM) on control and obstetric health outcomes.In this multicentre, open-label, randomised controlled trial, we recruited aged 18-40 years minimum 12 months were receiving intensive insulin therapy. Participants pregnant (≤13 weeks 6 days'...
OBJECTIVE To compare glycemic control, quality of life, and pregnancy outcomes women using insulin pumps multiple daily injection therapy (MDI) during the Continuous Glucose Monitoring in Women With Type 1 Diabetes Pregnancy Trial (CONCEPTT). RESEARCH DESIGN AND METHODS This was a prespecified analysis CONCEPTT involving 248 pregnant from 31 centers. Randomization stratified for pump versus MDI HbA1c. The primary outcome change HbA1c randomization to 34 weeks’ gestation. Key secondary were...
Objective Perinatal epidemiological studies and outcomes are often reported on gestational week thresholds. This study aims to quantify investigate the association of each day at birth antenatal management, mortality respiratory extremely preterm infants. Design Retrospective cohort using National Neonatal Research Database. Setting England Wales. Patients 26 098 infants born <28 weeks age (GA) admitted neonatal units from 2010 2020. Interventions Antenatal care outcome measures for were...
Objective To study whether maternal cigarette smoking during pregnancy is associated with alterations in the growth of fetal lungs, kidneys, liver, brain, and placenta. Design A case-control study, operators performing image analysis blinded. Setting Study performed on a research-dedicated magnetic resonance imaging (MRI) scanner (1.5 T) participants recruited from large teaching hospital United Kingdom. Participants total 26 pregnant women (13 current smokers, 13 non smokers) were...
OBJECTIVE To determine if temporal glucose profiles differed between 1) women who were randomized to real-time continuous monitoring (RT-CGM) or self-monitored blood (SMBG), 2) used insulin pumps multiple daily injections (MDIs), and 3) whose infants born large for gestational age (LGA) not, by assessing CGM data obtained from the Continuous Glucose Monitoring in Women With Type 1 Diabetes Pregnancy Trial (CONCEPTT). RESEARCH DESIGN AND METHODS Standard summary metrics functional analysis...
We have used magnetic resonance imaging (MRI) to provide important new insights into the function of human placenta in utero. measured slow net flow and high oxygenation vivo, which are consistent with efficient delivery oxygen from mother fetus. Our experimental evidence substantiates previous hypotheses on effects spiral artery remodelling utero also indicates rapid venous drainage placenta, is because this outflow has been largely neglected past. Furthermore, beyond Braxton Hicks...
The CONCEPTT trial compared real-time Continuous Glucose Monitoring (RT-CGM) to capillary glucose monitoring in pregnant women with type 1 diabetes. We analyzed CGM and glycated hemoglobin (HbA1c) measures first (n = 221), second 197), third 172) trimesters, aiming examine target attainment associations pregnancy outcomes. targets were Time-in-range (TIR) > 70%, Time-above-range (TAR) <25%, Time-below-range (TBR) < 4%, HbA1c 6.5% (National Institute for Health Care Excellence [NICE]) 6.0%...
To determine the incidence of, and complication rates from, impacted fetal head at full dilatation Caesarean birth in UK, record what techniques were used.Prospective observational study using UK Obstetric Surveillance System (UKOSS).159 (82%) of 194 hospitals with obstetric units.All women who underwent second stage between 1st March 31st August 2019. Further information was collected on cases where a dis-impaction technique used, or operating surgeon experienced 'difficulty' delivering...
Key content Asylum seekers and refugees are a vulnerable group with regards to pregnancy outcomes accessing maternity care. who pregnant living in the UK face medical, sexual psychosocial challenges, including dispersal late pregnancy. The health needs of asylum complex but similar other deprived ethnic minority communities UK. Asylum‐seeking women three times more likely die childbirth up four experience postnatal depression than general population because combination physical,...
A cesarean scar pregnancy is an iatrogenic consequence of a previous delivery. The gestational sac implants into niche created by the incision delivery, and this carries substantial risk for major maternal complications. aim study was to report, analyze, compare effectiveness safety different treatments options pregnancies managed in first trimester through registry.
Introduction Wales has higher rates of bowel cancer incidence and mortality than other UK nations, with over 2300 new cases 900 deaths annually. Regional disparities in underscore the need for a better understanding patient experiences care as well exploring potential areas improvement. This evaluation aimed to explore individuals history their caregivers Wales, UK, examining diagnosis, treatment aftercare. The study also explored caregiver recommendations inform improvements service...
To assess the reliability of magnetic resonance imaging (MRI) to measure fetal fat volume in utero, and study growth women with without diabetes view increased prevalence macrosomia former.We studied 26 pregnant women, 14 pre-gestational 12 non-diabetic controls. Fetal assessment took place at 24 weeks' gestation again 34 weeks by standard ultrasound biometry followed MRI 1.5 T. was determined from T1-weighted water-suppressed images using a semi-automated approach based on pixel intensity...
To understand current practice, expertise and training requirements for management of an impacted fetal head (IFH) at caesarean section (CS) in the UK, whether a clinical trial techniques to manage IFH is acceptable.Five hundred thirty-eight online surveys were completed by obstetricians (n = 206), obstetric anaesthetists 38), midwives 35) parents 259). Data was collected on incidences CS IFH, use techniques, acceptability from health care professionals. Information recollection likelihood...
Article1 January 1935THE INCIDENCE OF STREPTOCOCCAL INFECTION IN CARDIOVASCULAR SCLEROSISN. W. JONES, M.D., F.A.C.P., A. L. ROGERS, A.B.N. F.A.C.P.Search for more papers by this author, A.B.Search authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-8-7-834 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThere is a form of cardiovascular disease, seen frequently than that due...