A5045372653- Bone Tissue Engineering Materials
- Oral microbiology and periodontitis research
- Orthopedic Infections and Treatments
- Oral Health Pathology and Treatment
- Reproductive tract infections research
- Antimicrobial agents and applications
- Antimicrobial Peptides and Activities
- Renal Diseases and Glomerulopathies
- Clusterin in disease pathology
- Bacteriophages and microbial interactions
- Urinary Tract Infections Management
- Cervical Cancer and HPV Research
- Dental Health and Care Utilization
- Salivary Gland Disorders and Functions
- Orthopaedic implants and arthroplasty
- Appendicitis Diagnosis and Management
- Bacterial biofilms and quorum sensing
- 3D Printing in Biomedical Research
- Otolaryngology and Infectious Diseases
- Spectroscopy Techniques in Biomedical and Chemical Research
- Chronic Kidney Disease and Diabetes
- TiO2 Photocatalysis and Solar Cells
- Polymer Synthesis and Characterization
- Streptococcal Infections and Treatments
- Gut microbiota and health
Riga Stradiņš University
2016-2025
Riga Technical University
2017
Vaginal concentrations of mannose-binding lectin (MBL) and possession a polymorphism in codon 54 the MBL gene were determined 42 women with recurrent vulvovaginal candidiasis (RVVC) 43 control subjects. Reduced vaginal levels an increased occurrence present RVVC.
A C-->T substitution at position -589 in the interleukin-4 (IL-4) gene is associated with increased production of IL-4. Associations between this polymorphism and recurrent vulvovaginal candidiasis (RVVC), as well vaginal concentrations IL-4 anticandidal compounds nitric oxide (NO) mannose binding lectin (MBL), were evaluated.Vaginal samples obtained by lavage from 42 women RVVC during acute stage disease 43 control assayed enzyme-linked immunosorbent assay for NO metabolites. The was...
There is considerable interest in the use of bacteriophages (phages) to treat Pseudomonas aeruginosa infections associated with left ventricular assist devices (LVADs). These are often challenging manage due high rates multidrug resistance and biofilm formation, which could potentially be overcome phages. We report a case 54-year-old man relapsing multidrug-resistant P. LVAD driveline infection, who was treated combination two lytic antipseudomonal phages administered intravenously locally....
High-energy trauma with severe bone fractures can be complicated by infection, leading to the development of osteomyelitis. Pseudomonas aeruginosa is an important causative agent such infections because its high virulence profile and ability develop resistance against a wide range antimicrobials quickly. P. biofilms cause treatment failure relapsing infections. Bacteriophages are viruses that used treat biofilm-associated Moreover, combination phages certain have demonstrated synergistic...
Abstract Background . To investigate the correlation of reproductive tract infections (RTI) and endogenous vaginal flora at first antenatal consultation with placental histological inflammation. Methods In a follow‐up study, 154 low risk women no miscarriage factors were examined for presence Neisseria gonorrhoeae , Trichomonas vaginalis Chlamydia trachomatis Ureaplasma urealyticum Mycoplasma hominis Gardnerella Streptococcus agalactiae (GBS), Staphylococcus aureus Enterococcus faecalis...
Background and Objective: Tonsillar crypts can be considered a reservoir for variety of bacterial species. Some species part the normal oropharyngeal microbiota. The roles other pathogens, example, so-called non-oral respiratory pathogens Staphylococcus aureus, Klebsiella, Pseudomonas, Acinetobacter spp., which have strong virulence factors, biofilm production capacity, ability to initiate infectious diseases, are unclear. purpose this study was detect presence S. K. pneumoniae, P....
In society, tobacco products, such as e-cigarettes, and smokeless snus nicotine pouches, are becoming more attractive. There is still a lack of information regarding the effects these products on oral mucosa saliva biomarkers. The aim this study to evaluate presence inflammatory biomarkers IL-6, IL-1, IL-8, TNF alpha LRG-1 in saliva. Respondents were divided four groups based their product usage. Oral examination was carried out, samples taken, detection levels out. Out users, 30.8% 48.7%...
Titanium (Ti) is widely recognized for its exceptional properties and compatibility with medical applications. In our study, we successfully formed laser-induced periodic surface structures (LIPSS) on Ti plates a periodicity of 520-740 nm height range 150-250 nm. To investigate the morphology chemical composition these surfaces, employed various techniques, including field emission scanning electron microscopy, energy dispersive X-ray spectroscopy, atomic force photoelectron Raman...
Purpose: This prospective, single-center cohort study analyzes the potential of inflammatory protein mediator leucine-rich alpha-2 glycoprotein 1 (LRG1) for early and accurate diagnosis acute appendicitis (AA), differentiation complicated (AcA) from uncomplicated (AuA). Methods: Participants were divided into AcA, AuA, control groups, their serum (s-LRG1) urine LRG1 (u-LRG1) levels assayed preoperatively on second fifth postoperative days. Results: 153 patients participated, 97 had AA....
Background: Despite the widespread use of antibiotics to treat infected tonsils, episodes tonsillitis tend recur and turn into recurrent (RT) or are complicated by peritonsillar abscesses (PTAs). The treatment RT PTAs remains surgical, tonsillectomies still relevant. Materials methods: In a prospective, controlled study, we analyzed bacteria tonsillar crypts 99 patients with 29 PTA. We performed biofilm formation antibacterial susceptibility testing strains isolated from study patients....
To study the microbial characteristics of patients with pelvic inflammatory disease (PID) and possible impact an intrauterine device (IUD) on environment in women presenting PID.
Background and Objectives. The aim of this study is to determine the prevailing microbiota in samples from pediatric patients with acute appendicitis, as well evaluate antibacterial sensitivity isolated microorganisms, comparing data obtained clinic's therapy guidelines. Materials Methods. group consisted 93 between ages 7 18. All underwent a laparoscopic or conventional appendectomy. children were hospitalized signs symptoms suggestive appendicitis. Microbiological cultures appendix...
Escherichia coli is a common cause of biofilm-associated urinary tract infections. Bacteria inside the biofilm are more resistant to antibiotics. Six E. strains isolated from patients with infections were screened for biofilm-forming capability and antimicrobial susceptibility. Two most significant biofilm-producing selected minimal inhibitory concentration eradication in vitro testing using amoxicillin-clavulanic acid, ciprofloxacin, three commercial bacteriophage cocktails...
Abstract The prevention of COVID-19, caused by SARS-CoV-2, involves reducing transmission infectious respiratory droplets and aerosols with different methods, including the use face masks. There have been a variety studies published about effectiveness masks — they recognised as an inexpensive yet expedient method. In this research we aimed to investigate microbial contamination used compare results based on mask usage time determine efficiency facial against COVID-19. Microbiological 51 was...
IgA nephropathy (IgAN) is characterised by the production of galactose-deficient IgA1 (GdIgA1) antibodies. As source pathogenic antibodies, B cells are central to IgAN pathogenesis, but cell activation pathways as well potential dysregulated IgA-secretion remain unknown.
Objective. To study the microbial characteristics of patients with pelvic inflammatory disease (PID) and possible impact an intrauterine device (IUD) on environment in women presenting PID. Methods. Case‐control study, investigating 51 acute PID 50 healthy women. Endocervical specimens for microbiological investigation were obtained at gynaecological examination. Results. IUD users had significantly more Fusobacteria spp. Peptostreptococcus than non‐IUD The finding combinations several...
Background: European Higher Education institutions are expected to adopt a three-cycle system of Bachelor, Master and Doctor degrees as part the Bologna Process. Tuning methodology was previously used by MEDINE Thematic Network gain consensus on core learning outcomes (LO) for primary medical (Master Medicine) across Europe.
Peritonitis caused by Staphylococcusaureus is of major importance in peritoneal dialysis (PD) patients due to its great virulence profile and biofilm formation ability. Bacteriophages are a potential tool treat peritonitis resulting from biofilm-associated infections. We screened S. aureus colonization 71 PD the nasal cavity, groin, exit-site regions analyzed clinical outcomes these patients. performed biofilm-formation testing different strains compared isolates one patient detect...
BACKGROUND:Kidney transplantation is the treatment of choice for most patients with end-stage renal disease. To improve patient and transplant survival, non-invasive diagnostic methods different pathologies are important. Leucine-rich alpha-2-glycoprotein (LRG-1) an innovative biomarker that elevated in cases angiogenesis, inflammation, kidney injury. However, there limited data about role LRG-1 recipients. The aim this study was to evaluate association between serum LRG-1, urine function...
Cleft lip and palate are amongst the most common congenital malformations worldwide presenting with variable manifestations. Previous research has been primarily focused on genetical aspects of its complex multifactorial etiology. In present study, we investigated role cytokines as mediators epithelial–mesenchymal crosstalk local site inflammation in cleft affected infants. Lip material was obtained from 12 children aged before primary dentition who suffered orofacial clefting. The...
Extrusion is a perspective forming technology for obtaining objects with certain profile, important the TiO2 application as biomaterial. Extruded samples were calcinated at 1100 °C, thermally treated in different atmospheres: 1450 °C air and 1300 vacuum. An approach was made to examine adhesion colonization intensity of Staphylococcus epidermidis Pseudomonas aeruginosa on ceramic vitro. It found that Ps.aeruginosa demonstrated higher S.epidermidis vacuum attachment microorganisms air....