- Acute Kidney Injury Research
- Myasthenia Gravis and Thymoma
- Parkinson's Disease and Spinal Disorders
- Dialysis and Renal Disease Management
- Air Quality and Health Impacts
- Cancer Treatment and Pharmacology
- Toxic Organic Pollutants Impact
- Pituitary Gland Disorders and Treatments
- Noise Effects and Management
- Heart Failure Treatment and Management
- Mental Health Research Topics
- Viral Infections and Outbreaks Research
- Tryptophan and brain disorders
- Multiple Sclerosis Research Studies
- Per- and polyfluoroalkyl substances research
- Chronic Kidney Disease and Diabetes
- Biomedical Research and Pathophysiology
- Cardiac Arrest and Resuscitation
- Poisoning and overdose treatments
- Invertebrate Taxonomy and Ecology
- Treatment of Major Depression
- Central Venous Catheters and Hemodialysis
- Effects of Vibration on Health
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
Alexion Pharma (Switzerland)
2024-2025
AstraZeneca (Brazil)
2024-2025
Alexion Pharmaceuticals (United States)
2025
University of Illinois Chicago
2016-2024
Baxter (United States)
2020-2023
University of Liège
2023
Health Outcomes Solutions (United States)
2020
Patients with major depressive disorder who do not respond to ≥2 different pharmacological treatments within the current episode are considered have treatment resistant depression (TRD). This analysis determined meaningful change thresholds (MCT) of Patient Health Questionnaire (PHQ-9) and Montgomery-Åsberg Depression Rating Scale (MADRS) using anchor-based methods compared proportions changes in patients TRD across groups from two Phase 3 trials for esketamine nasal spray (SPRAVATOTM).Data...
Environmental lead exposure detrimentally affects children's educational performance, even at very low blood levels (BLLs). Among children in Chicago Public Schools (CPS), the severity of effects BLL on reading and math vary by racial subgroup (White vs. Hispanic non-Hispanic Black). We investigated impact standardized test performance (Mexican, Puerto Rican, Other Hispanic).We examined 12,319 born between 1994 1998 who were tested for birth 2006 enrolled 3rd grade a CPS school 2003 2006....
Introduction: The burden of persistent (≥3 days) severe AKI (PS-AKI) is poorly described among inpatients with stage 2–3 in the ward or ICU. Quantification could motivate targeted interventions to decrease duration these high-risk patients. Methods: This retrospective cohort study included adult patients discharged from January 1, 2017, December 31, 2019, US hospitals PINC AI Healthcare Database. Patients KDIGO 2 3 AKI, length stay ≥3 days, serum creatinine measures, and no history renal...
Acute kidney injury (AKI) and fluid overload (FO) are among the top reasons to initiate intermittent hemodialysis (IHD) or continuous renal replacement therapy (CRRT). Prior research suggests CRRT provides more precise volume control, but whether is cost-effective remains unclear. We assessed cost-effectiveness of for control compared with IHD from a U.S. healthcare payer perspective.Decision analytical model comparing health outcomes costs versus initiation AKI patients FO. The had an...
Key Points Among hospitalized patients with stage 2/3 AKI, persistent severe acute kidney injury (PS-AKI) is associated significantly longer length of stay (LOS) and higher costs during index hospitalization 30 days postdischarge. Relative differences in LOS for PS-AKI versus NPS-AKI were similar intensive care (ICU) non-ICU patients. Preventing among AKI may reduce hospital costs. Background Persistent worse clinical outcomes, but there are no data on PS-AKI. We compared health resource...
Abstract Introduction The Theranova 400 is a medium cut‐off dialyzer that allows for superior clearance of larger middle molecules than traditional high‐flux dialyzers. This study evaluates the association expanded hemodialysis (HDx) using versus conventional (HD) with on hospitalization rates and healthcare costs as compared to HD in post hoc analysis randomized controlled trial. Methods In non‐concealed, 24‐week clinical trial, maintenance patients were receive treatment either or similar...
The impact of the 2014–2016 Ebola epidemic in West Africa on human immunodeficiency virus (HIV) treatment Sierra Leone is unknown, especially for groups with higher HIV prevalence such as military. Using a retrospective study design, clinical outcomes were evaluated prior to and during 264 HIV-infected soldiers Republic Armed Forces (RSLAF) their dependents receiving at primary RSLAF clinic. Medical records abstracted baseline data clinic attendance. Estimated risk lost follow-up (LTFU),...
To characterize the comorbidity burden and steroid usage patterns in Medicare fee-for-service beneficiaries with generalized myasthenia gravis (gMG) US.
Assess disease outcomes and changes in corticosteroid use patients with gMG receiving C5ITs.
Exposure to polychlorinated biphenyls (PCBs) has been linked risk factors for cardiovascular disease such as increased inflammation, accelerated atherosclerosis, diabetes, and sex hormone dysregulation. Furthermore, there is increasing evidence suggesting associations between internal dose of PCBs outcomes.
The objective of this study is to explore the impact socioeconomic factors on risk ≥2-year delayed diagnosis NMOSD.
INTRODUCTION: Cardiovascular disease remains the leading cause of death in United States and world. Exposure to persistent organic pollutants has been linked risk factors for cardiovascular such as increased inflammatory markers, accelerated atherosclerosis, sex hormone dysregulation. Furthermore, there is increasing evidence suggesting associations internal doses with outcomes. METHODS: The Great Lakes Sport-Caught Fish Consumption cohort was established early 1990's. Eight hundred thirteen...
Hypothermia is a common adverse event during continuous renal replacement therapy (CRRT), affecting multiple organ systems and increasing risk of poor health outcomes among patients with acute kidney injury (AKI) undergoing CRRT. TheraMax blood warmers are the next generation extracorporeal which reduce hypothermia The purpose this study to elucidate potential economic impacts avoiding CRRT-induced by using novel TherMax warming device. This compares care costs associated use new warmer unit...