A5041589934- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Optical Sensing Technologies
- Optical Coherence Tomography Applications
- Spectroscopy and Chemometric Analyses
- Optical Imaging and Spectroscopy Techniques
- Biosensors and Analytical Detection
- Laser-induced spectroscopy and plasma
- Photoacoustic and Ultrasonic Imaging
- Mineralogy and Gemology Studies
- Microfluidic and Capillary Electrophoresis Applications
- Forensic Fingerprint Detection Methods
- Ocular and Laser Science Research
- Analytical Chemistry and Sensors
University of Oulu
2018-2023
Abstract Raman analysis of rock samples containing rare earth elements (REEs) is challenging due to the strong fluorescence, which may mask weaker signal. In this research, time‐gated (TG) has been applied construction mineral distribution map from REE‐bearing rock. With TG Raman, material excited with a short subnanosecond laser pulse, and signal collected within picosecond‐scale time window prior formation fluorescent by means single‐photon avalanche diode array. This allows readout...
Improvement to the spectral quality of Rama images human teeth were achieved with a time-resolved CMOS SPAD-based Raman spectrometer.
Raman spectroscopy has proved to have potential in deep surface analytical applications. We present here, the best of our knowledge, first time depth analysis semi-transparent media by a depth-resolving spectrometer based on an adjustable time-correlated CMOS SPAD (single-photon avalanche diode) line sensor that can measure target samples embedded centimeter-scale medium simultaneously with normal profiling operation and suppress fluorescence background means picosecond gating. The...
Hydrogels, natural and synthetic origin, are actively studied for their use implants payload carriers. These biomaterials delivery systems have enormous potential in basic biomedical research, drug development, long-term of biologics. Nanofibrillated cellulose (NFC) hydrogels, both anionic (ANFC) ones, allow loading immediate controlled release via the slow dissolution solid crystals into hydrogel its subsequent release. This property makes NFC originated hydrogels an interesting non-toxic...
The fluorescence background in Raman spectroscopy can be effectively suppressed by using pulsed lasers and time-gated detectors. A recent solution to reduce the high complexity bulkiness of systems is implement detector utilizing time-resolved single-photon avalanche diodes (SPADs) fabricated complementary-metal-oxide-semiconductor (CMOS) technology. In this study, we investigate effects fluorescence-to-Raman ratio, recording time excitation intensity on quality spectra measured one furthest...
Remote Raman spectroscopy is widely used to detect minerals, explosives and air pollution, for example. One of its main problems, however, background radiation that caused by ambient light sample fluorescence. We present here, the best our knowledge, first time a distance-resolving radar device based on an adjustable, time-correlated complementary metal-oxide-semiconductor (CMOS) single-photon avalanche diode line sensor which can measure location target simultaneously with normal stand-off...
The capability of Raman imaging to produce 2D and 3D chemical presentations samples has gained a lot interest in different application fields. In this paper, we present image reconstruction based on scanning sample utilizing time-resolved spectrometer CMOS single-photon avalanche diode (SPAD) line sensor. data contains the lateral information (XY-plane) whereas time-of-arrival photons measured by sensor carries axial (i.e., depth information, Z-axis). is fabricated 110-nm technology. It...
A single burst depth-resolving Raman spectrometer based on a CMOS single-photon avalanche diode (SPAD) array with an on-chip 256-channel time-to-digital converter (TDC) has been developed to analyze heterogenous liquid sample without the need for any additional off-chip delay circuits. The depth derivation of sensitive layers top and under water phase is measuring time-of-arrivals scattered photons generated short laser pulses (~150 ps) by utilizing 256 TDCs at every spectral points. spectra...
Dental caries is the most widespread non-communicable disease affecting 2.5 billion people worldwide. Recently various optical spectroscopy methods have gained a lot of interest in dental research and detection due to their noninvasive nonionizing nature. We demonstrate here, best our knowledge, for first time simultaneous Raman, fluorescence intensity lifetime imaging carious human enamel with single device based on time-resolved single-photon avalanche diode (SPAD) sensor fabricated 110-nm...