- Spinal Dysraphism and Malformations
- Nerve Injury and Rehabilitation
- Family and Disability Support Research
- Child and Adolescent Psychosocial and Emotional Development
- Attachment and Relationship Dynamics
- Family Dynamics and Relationships
- Breastfeeding Practices and Influences
- Neurofibromatosis and Schwannoma Cases
- Spinal Cord Injury Research
- Early Childhood Education and Development
- Maternal Mental Health During Pregnancy and Postpartum
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Intergenerational Family Dynamics and Caregiving
- Kruppel-like factors research
- Connective tissue disorders research
- Plant-based Medicinal Research
- Facial Nerve Paralysis Treatment and Research
- Circular RNAs in diseases
- Psychosocial Factors Impacting Youth
- Thermoelastic and Magnetoelastic Phenomena
- Sustainable Urban and Rural Development
- Pelvic and Acetabular Injuries
- Educational Research and Pedagogy
- Real-Time Systems Scheduling
Zhejiang Chinese Medical University
2020-2025
Zhejiang Cancer Hospital
2025
Chinese Academy of Sciences
2025
Chinese PLA General Hospital
2023-2024
Brigham and Women's Hospital
2024
PLA Academy of Military Science
2022-2023
Qingdao Eighth People's Hospital
2018-2023
University of Nebraska–Lincoln
1995-2022
East China Normal University
2018
Shanghai Key Laboratory of Trustworthy Computing
2018
Context Sepsis-induced acute lung injury (ALI) is associated with high morbidity and mortality. Rhodiola rosea L. (Crassulaceae) (RR) its extracts have shown anti-inflammatory, antioxidant, immunomodulatory, lung-protective effects.
Background Macrophage polarization and microRNA play crucial roles in the development of atherosclerosis (AS). The M1 macrophage phenotype contributes to formation plaques, while M2 resolves inflammation promotes tissue repair. MiR-126 has been found a role regulating context AS. However, exact mechanism miR-126 requires further research. Methods foam cell model was established by stimulating THP-1 with oxidized low-density lipoprotein (ox-LDL). We transfected cells mimic its negative...
Radiotherapy is one of the main treatments for colorectal cancer (CRC), but due to intrinsic resistance cells or caused by long-term radiotherapy, effectiveness this treatment limited some CRC patients. Consequently, identifying novel sensitization strategies essential. This study identifies Noxa1 as a marker linked radiotherapy in CRC, suggesting its potential prognostic biomarker patients with CRC. The found that was significantly overexpressed radiotherapy-resistant patients, correlating...
The coparenting subsystem is important for the psychosocial development of young children. In this article, we used cross-lagged structural equation modeling to assess bidirectional relations between unmarried parents' cooperative and their children's behavioral problems. Using a subsample 788 dyads poor, parents children from Fragile Families Child Wellbeing data, examined trends in problems over time (in ages 1, 3, 5, 9 years) reciprocal effects these 2 variables. All pathways at 1 point...
Investigations on the bidirectional relationships between parenting stress and child behavior problems are important to inform intervention strategies; however, prior research has provided inconsistent findings. Using a national sample of multi-stressed single-mother families from Fragile Families Child Wellbeing study, present study examined maternal children's behavioral spanning early childhood through adolescence at child's ages 3, 5, 9, 15. Reciprocal transactions were found in 3 5....
MicroRNAs (miRNAs) have been proven to important effects on the proliferation and metastasis of multiple cancers, including hepatocellular carcinoma (HCC). In present study, our aim was explore biological function miR-106b in HCC cell metastasis. qPCR analysis showed that expressed at higher levels, while disabled homolog 2 (DAB2) lower levels tissues cells. Moreover, aberrant expression affected proliferative migratory ability by MTT Transwell assay. DAB2 identified as a specific target...
Peripheral nerve injury poses a great threat to neurosurgery and limits the regenerative potential of sacral nerves in neurogenic bladder. It remains unknown whether electrical stimulation can facilitate regeneration addition modulate bladder function. The objective this study was utilise sacra crush with newly constructed electroconductive scaffold explore role macrophages crushed nerves. As result, we generated polypyrrole-coated polycaprolactone/silk fibroin through which applied...
Abstract Objective The purpose of this study was to identify significant prognostic factors associated with facial paralysis after vestibular schwannoma (VS) surgery and develop a novel nomogram for predicting nerve (FN) outcomes. Methods Retrospective data were retrieved from 355 patients who underwent microsurgery via the retrosigmoid approach VS between December 2017 2022. Univariate multivariate logistic regression analysis used construct radiographic features‐based predict risk surgery....
Introduction Observational studies have yielded inconsistent findings regarding the correlation between bone mineral density (BMD) and various spinal disorders. To explore relationship total-body BMD disorders further, we conducted a Mendelian randomization analysis to assess this association. Methods Two-sample bidirectional (MR) was employed investigate association The inverse-variance weighted (IVW) method used as primary effect estimate, additional methods, including median, MR-Egger,...
The number of novice kindergarten teachers with bachelor’s degrees in China has grown significantly over the past decade. From 2011 to 2021, graduates majoring early childhood education increased by 230,000, reflecting a rapid expansion degree holders. However, since 2022, enrollment programs declined, partly due growing struggling job adaptation. This highlights need for support career preparation and adaptation.This study examines challenges faced these during their initial stages how they...
Abstract Background : This study aimed to investigate the treatment and curative effects of thoracic anterior spinal cord herniation. Methods Clinical data 7 patients with herniation were represented. All diagnosed a complete pre-operative examination scheduled for surgical treatment. In addition, regular follow-up was performed after surgery, operation’s efficacy evaluated according clinical symptoms, imaging findings, improvement in neurological function. Results: underwent release an...
Background : Glial cell line derived neurotrophic factor (GDNF) is a potent factor, which has been shown to affect the metastasis and invasion of cancer cells. The molecular mechanism GDNF still unclear. Here, we investigate embedded in chitosan (CS) nano lipid carrier colorectal cancer. Methods Electron microscopy was used detect relationship between characteristics coated carrier, MTT apoptosis tests were effect expression on proliferation ability intestinal cells, immunofluorescence NF-KB...
Neuroblastoma (NB) is a leading cause of death in children. It usually occurs the adrenal gland and rarely spinal canal. Here, we report case 48-year-old male patient with abnormal thickening cauda equina nerve as revealed by lumbosacral magnetic resonance imaging. The patient's main clinical manifestations were numbness pain both lower limbs. underwent surgical treatment; however, intraoperatively, an unclear border was observed between tumor; therefore, tumor not forcibly excised....
Ensuring the reliability of concurrency software systems is difficult due to interaction between threads. This article discusses requirements for formal verification concurrent embedded and proposes a constraint-based flow-sensitive static analysis avionics by iteratively composing thread-modular abstract interpreters. These constraint are based on data-flow graphs used rule out patterns thread interference that can not occur in real program execution. Our new method has advantage being more...
Abstract Background: Compared with foreign countries, China's education evaluation system mostly adopts the method of simple comparison students' average scores, and results are relatively simple; It is a top-down, one-way appraisal system, which not only can form information feedback network, but also fully mobilize enthusiasm initiative subject object. As value-added model, TVAAS provide multi-dimensional has been widely used in countries. Therefore, we need to learn from Tennessee model...