- Circular RNAs in diseases
- MicroRNA in disease regulation
- RNA Research and Splicing
- Gastrointestinal disorders and treatments
- Immune cells in cancer
- Colorectal Cancer Surgical Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Tracheal and airway disorders
- Oral and gingival health research
- Metastasis and carcinoma case studies
- Gastrointestinal Tumor Research and Treatment
- S100 Proteins and Annexins
- Advanced Radiotherapy Techniques
- Hedgehog Signaling Pathway Studies
- Colorectal and Anal Carcinomas
Wenzhou Medical University
2024
First Affiliated Hospital of Wenzhou Medical University
2024
Children's Hospital of Zhejiang University
2024
Sixth Affiliated Hospital of Sun Yat-sen University
2022
Sun Yat-sen University
2022
Zhejiang Chinese Medical University
2018-2019
Colorectal cancer (CRC) and inflammatory bowel disease (IBD) are escalating global health concerns. Despite their distinct clinical presentations, both disorders share intricate genetic molecular interactions. The Hippo signaling pathway plays a crucial role in regulating cell processes is implicated the pathogenesis of IBD CRC. Circular RNAs (circRNAs) have gained attention for roles various diseases, including However, comprehensive understanding specific circRNAs involved CRC, functional...
Chemoresistance remains a big challenge in hepatocellular carcinoma (HCC) treatment. Several studies indicated that RNA-binding protein Lin28B serves an oncogenic role HCC, but its activity HCC chemotherapy has never been assessed. In this study, we found overexpression of significantly increased the paclitaxel chemoresistance two different cells lines while silencing reduced paclitaxel-resistance cells. Curcumin, natural anti-cancer agent, sensitivity to through inhibiting NF-κB stimulated...
Abstract Chemoresistance remains a big challenge in hepatocellular carcinoma (HCC) treatment. Several studies indicated that RNA-binding protein Lin28B serves an oncogenic role HCC, but its activity HCC chemotherapy has never been assessed. In this study, we found overexpression of significantly increased the paclitaxel chemoresistance two different cells lines while silencing reduced paclitaxel-resistance cells. Curcumin, natural anti-cancer agent, sensitivity to through inhibiting NF-κB...
Background Chronic radiation proctopathy (CRP) is a common complication after therapy for pelvic malignancies. Compared with diversion surgery, resection surgery removes the damaged tissue completely to avoid risks of recurrence and improve patients' outcome. Hence, could be an optimal surgical approach when CRP complicated by late complications. This study aimed describe modified procedure report its preliminary efficacy safety in treating patients Methods We retrospectively reviewed who...
Objective To investigate the clinical characteristics, surgical treatment and outcome for patients with duodenal stromal tumor. Methods Data of 40 tumor duodenum were reviewed retrospectively. Results All received resection including local in 14 cases, segmental 17 pancreaticoduodenectomy 9 cases. 38 cases followed-up, two lost. The median follow-up was 59 months (range 3-240 mos). 1, 3, 5-year overall survival rates 92%, 76% 68%, respectively. No recurrence found very-low-risk...