A5039630283- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Research on Leishmaniasis Studies
- Cell Adhesion Molecules Research
- Wound Healing and Treatments
- Urologic and reproductive health conditions
- Dermatological diseases and infestations
- Virus-based gene therapy research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Pneumothorax, Barotrauma, Emphysema
- Bone Tumor Diagnosis and Treatments
- Aortic Thrombus and Embolism
- Aortic Disease and Treatment Approaches
- Blood Coagulation and Thrombosis Mechanisms
- Pediatric Urology and Nephrology Studies
- Extracellular vesicles in disease
- Vector-Borne Animal Diseases
- Infectious Diseases and Mycology
- Kidney Stones and Urolithiasis Treatments
- Cancer and Skin Lesions
- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
- Musculoskeletal synovial abnormalities and treatments
- Trypanosoma species research and implications
- Immune Response and Inflammation
Universidad de Zaragoza
2021-2025
Centro de Investigación y Tecnología Agroalimentaria de Aragón
2025
Advanced medicated wound dressings fabricated by electrospinning and electrospraying were prepared for the eradication of topical bacterial infections potentially applied in management infected acute chronic non-healing wounds. Two different antibiotics (ciprofloxacin rifampicin), with aqueous solubilities mechanisms antimicrobial action, loaded within electrosprayed polymer microparticles electrospun nanofibers, respectively, to provide resulting dressing dually controlled antibiotic...
The main current challenges in oncology are (1) avoiding systemic side effects therapy, and (2) developing alternative treatment strategies for metastatic tumours. Nanomedicine was assumed to provide answers these issues, but delivering enough therapeutic nanoparticles (NPs) tumours still remains a huge challenge nanomaterials-based treatments. Extracellular vesicles (EVs) play key role cell communication processes can be combined with nanomaterials improve their targeting capabilities. In...
Small ruminant lentiviruses (SRLV) cause multisystemic chronic inflammatory disease and significant economic losses in sheep goats worldwide. However, no vaccines or therapies are currently available. In this study, a recombinant Sendai virus (SeV) vector encoding the SRLV gag-P25 gene (rSeV-GFP-P25) from EV1 strain was generated using In-FUSION cloning rescued SeV reverse genetic system. Transgene expression stimulation of innate immunity interferon-stimulated genes (ovine A3Z1, OBST2...
Intestinal dilatation syndrome (IDS) is a poorly described condition affecting layers and breeder hens globally. Its prevalence increasing, particularly in free-range systems, but the cause remains unknown. This retrospective study examined 35 from 3 flocks: flock A (n = 20) enriched-caged B 5), both affected by IDS, C 10), with no history of IDS. Clinicopathological studies were performed on these hens, metagenomic analysis was conducted proventriculus jejunum 2) 2). Based clinical signs...
Feline osteochondromatosis is a spontaneous osteocartilaginous exostosis associated with feline leukaemia virus (FeLV) infection or due to frameshift variant in the exostosin glycosyltransferase 1 (EXT1) gene. Osteochondromatosis was diagnosed an indoor-only, 12-year-old, neutered female, Russian Blue cat. Radiographs revealed bilateral calcified proliferations elbow, costochondral and sternochondral joints, which distorted normal skeletal structure. Grossly, proliferated joints presented...
The aortic lumen in healthy animals is characterized by a smooth, whitish surface, but sheep have macroscopic corrugation of the intimal surface thoracic aorta (TA). Our aim was to determine if this finding pathological or physiological. Thirteen aortas were included work together with from cattle (n = 3), goat 1), horses 4), dogs 2), rabbits 2) and pig 1). A corrugated TA seen all less evident cattle. Histologically, multifocal bulging areas that protruded into lumen. outer half tunica...
Canine leishmaniosis is a vector-borne disease caused by Leishmania infantum, and clinical manifestations of infection range from absent or severe to fatal result immune-mediated mechanisms. In dogs, the most common signs include skin lesions lymphadenomegaly. However, presence other nontypical has been described, diagnosing these cases can be challenging. The aim present short communication was describe impact formation circulating immunocomplexes due L. infantum in dog with affected...
Malakoplakia is a rare chronic granulomatous disease usually affecting the urinary bladder and other locations. In humans, gastrointestinal tract second most common location but there are no reports of intestinal malakoplakia in animals. A 10-month-old female French Bulldog was presented with haemorrhagic diarrhoea anorexia normochromic-normocytic anaemia hypoalbuminaemia. Grossly, mucosal thickening ulceration caecum, colon rectum. Microscopically, transmural sheets foamy macrophages were...
Mannheimia haemolytica–associated abomasitis has been clinically described as a cause of sudden death in lambs, but it is poorly characterized. We describe the pathological features severe fibrinonecrotizing 3 lambs that died suddenly. All abomasums had thickened submucosa due to edema and necrotic areas delimited by bands degenerate neutrophils with slender nuclei (oat cells) angiocentric distributions. The overlying mucosa was congested. Myriads gram-negative coccobacilli were observed...
Abstract A 1.5-year-old male Iberian lynx born in captivity presented with a 2.2 cm exophytic nodular alopecic mass at the left tarsus medial aspect, before being released into wild. The lesion had keratinised material protruding through 1.2 pore, forming cutaneous horn. Histopathology revealed cystic dermo-epidermal lined by psoriasiform hyperplasia of epithelium, thicker base cyst, together abrupt to progressive keratinization and keratin pearls. central cavity was filled fibrillary ghost...
Abstract Canine leishmaniosis, caused by the protozoan Leishmania infantum , is an endemic vector‐borne disease in Europe. From a diagnostic point of view, can sometimes be real challenge for clinician, due to variability clinical presentations sick dog. These signs classified, based on frequency presentation, typical and atypical signs. In dogs common find different cutaneous systemic involvement, while mucosa are not so common. A 6‐year‐old, entire, male German shepherd crossbred dog was...